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Book
An introduction to forensic genetics
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ISBN: 9780470710180 9780470710197 Year: 2011 Publisher: Chichester, West Sussex, UK : Wiley-Blackwell,

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Dissertation
Microsatellite instability profiling of Lynch syndrome-associated cancers.
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Year: 2009 Publisher: Groningen Grafimedia facilitait bedrijf RUG

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Dissertation
Heritable risk factors for generalized and cutaneous lupus erythematosus
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Year: 2001 Publisher: Leiden s.n.

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Dissertation
Microsatellites in the human major histocompatibility complex
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Year: 1998 Publisher: Enschede PrintPartners Ipskamp

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Dissertation
Genetic diversity, mating type, aneuploid sexual reproduction and survivial of Phytophthora ramorum
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ISBN: 9789059893610 Year: 2010


Book
Genetic and Phenotypic Variation in Tree Crops Biodiversity
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Recently, there has been a dramatic increase in the use of DNA-derived data and innovative phenotyping to obtain insights into the causative genes underlying traits of agronomical interest or to characterize tree genetic resources. The latter, in particular, could represent an important source of genetic diversity that can be readily used to enhance the adaptability to limiting environmental factors and resistance to biotic stresses or to promote novel genotypes with improved agronomic traits. On the whole, the studies collected in this book report on tree crop biodiversity characterization that could provide the essential building blocks to ensure future improvements in production and quality, as well as for innovations in tree crop development and utilization.

Keywords

Research & information: general --- Biology, life sciences --- Microbiology (non-medical) --- Camellia sinensis --- genetic diversity --- population structure --- SSR --- bark phenotype --- bark scale --- Norway spruce --- resonance wood --- sonic tomography --- conifer adaptation --- phenotypic plasticity --- comparative proteomics --- stress response --- Hainan Province --- endemic species --- conservation --- codon usage --- sequence divergence --- phylogeny --- Acer --- sect. Platanoidea --- chloroplast genome --- structural variation --- phylogenetics --- nSSR --- cpDNA --- Magnoliaceae --- conservation genetics --- fragmentation --- agroforestry --- domestication --- Inga edulis --- amazon forest --- microsatellite markers --- Paeonia rockii (flare tree peony) germplasm accessions --- phenotypic traits --- EST-SSR markers --- chloroplast DNA sequences --- tree improvement --- evergreen oak --- phenotypic selection --- selection criteria --- seed orchard --- generalized value --- genetic differentiation --- natural regeneration --- cultivated population --- semi-domesticated population --- growth trait --- wood property --- cytosine methylation --- epimarker --- candidate gene --- gene expression --- color mutation --- pigment metabolism --- chlorophyll --- anthocyanin --- mutation mechanism --- RNA-seq --- Castanopsis × kuchugouzhui --- natural hybrid --- molecular identification --- chloroplast DNA sequence --- microsatellite --- Ilex species --- Aquifoliaceae --- morphological traits --- DNA C-value --- plastid genome --- S-genotyping --- S-locus --- P. communis --- P. pyrifolia --- P. amygdaliformis --- genetic structure --- n/a


Book
Genetic and Phenotypic Variation in Tree Crops Biodiversity
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Recently, there has been a dramatic increase in the use of DNA-derived data and innovative phenotyping to obtain insights into the causative genes underlying traits of agronomical interest or to characterize tree genetic resources. The latter, in particular, could represent an important source of genetic diversity that can be readily used to enhance the adaptability to limiting environmental factors and resistance to biotic stresses or to promote novel genotypes with improved agronomic traits. On the whole, the studies collected in this book report on tree crop biodiversity characterization that could provide the essential building blocks to ensure future improvements in production and quality, as well as for innovations in tree crop development and utilization.

Keywords

Camellia sinensis --- genetic diversity --- population structure --- SSR --- bark phenotype --- bark scale --- Norway spruce --- resonance wood --- sonic tomography --- conifer adaptation --- phenotypic plasticity --- comparative proteomics --- stress response --- Hainan Province --- endemic species --- conservation --- codon usage --- sequence divergence --- phylogeny --- Acer --- sect. Platanoidea --- chloroplast genome --- structural variation --- phylogenetics --- nSSR --- cpDNA --- Magnoliaceae --- conservation genetics --- fragmentation --- agroforestry --- domestication --- Inga edulis --- amazon forest --- microsatellite markers --- Paeonia rockii (flare tree peony) germplasm accessions --- phenotypic traits --- EST-SSR markers --- chloroplast DNA sequences --- tree improvement --- evergreen oak --- phenotypic selection --- selection criteria --- seed orchard --- generalized value --- genetic differentiation --- natural regeneration --- cultivated population --- semi-domesticated population --- growth trait --- wood property --- cytosine methylation --- epimarker --- candidate gene --- gene expression --- color mutation --- pigment metabolism --- chlorophyll --- anthocyanin --- mutation mechanism --- RNA-seq --- Castanopsis × kuchugouzhui --- natural hybrid --- molecular identification --- chloroplast DNA sequence --- microsatellite --- Ilex species --- Aquifoliaceae --- morphological traits --- DNA C-value --- plastid genome --- S-genotyping --- S-locus --- P. communis --- P. pyrifolia --- P. amygdaliformis --- genetic structure --- n/a


Book
Gastrointestinal Cancers and Personalized Medicine
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Gastrointestinal cancers, such as esophageal and gastric cancers, pancreatic cancers, hepatobiliary cancers, colorectal cancers and gastrointestinal stromal tumors, are frequently diagnosed at an advanced stage and have a dismal prognosis. Even in patients with potentially curative cancer, nearly 50\% will develop recurrent disease despite aggressive treatments. A number of biomarkers currently guide treatment decisions for patients with gastrointestinal neoplasms. Major technological advances in genomics have made it possible to identify critical genetic alterations in cancer, furthering oncology along the path to “personalized cancer medicine”. Future research efforts will focus on the identification of new biomarkers, moving existing biomarkers into earlier lines of therapy and evaluating new combinations of existing biomarkers and therapies.The aim of this Special Issue is to provide an overview of exciting new research in the area of gastrointestinal tumors that may establish innovative personalized management and precision medicine modalities for individualized care.

Keywords

Medicine --- Pharmacology --- neutrophil-to-lymphocyte ratio --- lymphocyte-to-monocyte ratio --- prognosis --- rectal cancer --- mesorectum --- sphincter preserving --- molecular oncology --- precision medicine --- colorectal cancer --- targeted therapy --- molecular profiling --- pancreatic cysts --- thermal liquid biopsy --- differential scanning calorimetry --- diagnosis --- generalized linear models --- gene signature --- mRNA expression --- VANGL1 --- FFPE --- neurotoxicity --- oxaliplatin --- chemotherapy-induced peripheral neuropathy --- biomarker --- genomics --- neuropathy --- FOLFOX --- FOLFIRINOX --- XELOX --- gastrointestinal cancer --- LAG-3 --- immune checkpoint --- colon cancer --- survival --- microsatellite instability --- immunotherapy --- neutrophil-to-lymphocyte ratio --- lymphocyte-to-monocyte ratio --- prognosis --- rectal cancer --- mesorectum --- sphincter preserving --- molecular oncology --- precision medicine --- colorectal cancer --- targeted therapy --- molecular profiling --- pancreatic cysts --- thermal liquid biopsy --- differential scanning calorimetry --- diagnosis --- generalized linear models --- gene signature --- mRNA expression --- VANGL1 --- FFPE --- neurotoxicity --- oxaliplatin --- chemotherapy-induced peripheral neuropathy --- biomarker --- genomics --- neuropathy --- FOLFOX --- FOLFIRINOX --- XELOX --- gastrointestinal cancer --- LAG-3 --- immune checkpoint --- colon cancer --- survival --- microsatellite instability --- immunotherapy


Book
Gastrointestinal Cancers and Personalized Medicine
Authors: ---
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Gastrointestinal cancers, such as esophageal and gastric cancers, pancreatic cancers, hepatobiliary cancers, colorectal cancers and gastrointestinal stromal tumors, are frequently diagnosed at an advanced stage and have a dismal prognosis. Even in patients with potentially curative cancer, nearly 50\% will develop recurrent disease despite aggressive treatments. A number of biomarkers currently guide treatment decisions for patients with gastrointestinal neoplasms. Major technological advances in genomics have made it possible to identify critical genetic alterations in cancer, furthering oncology along the path to “personalized cancer medicine”. Future research efforts will focus on the identification of new biomarkers, moving existing biomarkers into earlier lines of therapy and evaluating new combinations of existing biomarkers and therapies.The aim of this Special Issue is to provide an overview of exciting new research in the area of gastrointestinal tumors that may establish innovative personalized management and precision medicine modalities for individualized care.

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