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Phagocytosis : microbial invasion
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ISBN: 1281060135 9786611060138 008052608X 0762306106 9780762306107 9780080526089 9781281060136 6611060138 Year: 1999 Publisher: Stamford, CT : JAI Press,

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Abstract

The present volume focuses on microbial invasion strategies of pathogen uptake. An accompanying volume (Vol. 5) in the series presents the phagocytic process from the viewpoint of the host cell. This field of study is growing rapidly after a somewhat slow start over recent decades. This collection of invited chapters attempts to reflect current research and brings together cell biologists, microbiologists, and immunologists with disthemes, hopefully like a symphony rather than a boring catalogue. It will be evident that editorial bias favors intracellular parasitism and medically important


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Current Trends in Immunity and Respiratory Infections
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ISBN: 3030016358 303001634X Year: 2018 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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The purpose of this book is to disseminate and deliberate on the latest knowledge concerning immunity and its role in protection and fight against microorganism invasion. The articles tackle both humoral and cellular immunity, and their interconnectivity. The former involves B cells that recognize invading pathogens and create the antibody-mediated response, which when memorized provides future immunity. The latter involves mostly T cells, exemplified by cytotoxic or killer cell destroying the pathogens, or helper cells stimulating B cells to produce antibodies to bind and neutralize the pathogens. T cells act through release of cytokines, interleukins, and other bioactive mediators. Neutrophils play a key role in innate immunity against bacterial infections. The process of NETosis is a recently unraveled sophisticated defense mechanism, consisting of the formation of neutrophil extracellular traps that catch, immobilize, and remove pathogens from the body. Dysfunction of immunity is indisputably conducive to the propensity for infections, particularly respiratory tract infections, as the airways are the first line of defense against invading pathogens. Pathogens can rapidly evolve and adapt to avoid detection by the immune system. The case in point is the influenza virus. The articles report on the epidemiology, diagnostics, serology, complications, and the process of acquired immunity due to vaccination against influenza and influenza-like infections in recent epidemic seasons. The book is a blend of medical research and practice. It is intended for academic scientists, research scholars, clinicians, family doctors, and healthcare professionals.

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