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This volume comprehensively covers new technologies and methodologies that have appeared for the study of mouse development. This volume is Part B of an update of volume 225, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993. Comprehensively covers new techniques for the cryopreservation of gametes and embryos, production of transgenic and null (knockout) animals (use of ES cells), generation of conditional/inducible mutant animals, use of gene-trap mutagenesis, analysis of allele-specific expression, use of

Developmental biology. --- Mice -- Cytology. --- Mice -- Development. --- Mice -- Embryology. --- Mice as laboratory animals. --- Molecular biology -- Technique. --- Mice. --- House mice --- House mouse --- Mouse --- Mus musculus --- Rodents --- Laboratory animals

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This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference.*Broad-based overview

Mice --- Mice as laboratory animals --- Souris --- Souris (Animaux de laboratoire) --- Development --- Physiology --- Développement --- Physiologie --- Développement --- ELSEVIER-B EPUB-LIV-FT --- Mice as laboratory animals. --- Laboratory animals --- House mice --- House mouse --- Mouse --- Mus musculus --- Rodents --- Development. --- Physiology. --- Mice - Development --- Mice - Physiology --- MICE --- GROWTH AND EMBRYONIC DEVELOPMENT --- FETAL DEVELOPEMENT --- ANIMALS, LABORATOY --- GROWTH AND DEVELOPMENT

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The mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originated from mouse embryology. Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse embryonic stem cells by Martin Evans (who received the Nobel Prize in medicine in 2007 for this achievement) Matthew Kaufman, and Gail Martin. This book provides an overview of mouse development, spanning from oocytes before fertilization to the state-of-the-art description of embryonic and adult stem cells. The chapters, written by the leading specialists in the field, deal with the most recent discoveries in this extremely fast-developing area of research.

Cytology. --- Life sciences. --- Mice -- Development. --- Stem cells. --- Mice --- Biology --- Cells --- Anatomy --- Murinae --- Biological Science Disciplines --- Muridae --- Natural Science Disciplines --- Rodentia --- Disciplines and Occupations --- Mammals --- Vertebrates --- Chordata --- Animals --- Eukaryota --- Organisms --- Stem Cells --- Cell Biology --- Zoology --- Health & Biological Sciences --- Biophysics --- Development --- Physiology. --- Development. --- House mice --- House mouse --- Mouse --- Mus musculus --- Medical genetics. --- Molecular biology. --- Cell biology. --- Developmental biology. --- Life Sciences. --- Developmental Biology. --- Stem Cells. --- Cell Biology. --- Gene Function. --- Molecular Medicine. --- Rodents --- Medicine. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Development (Biology) --- Growth --- Ontogeny --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Genetic disorders --- Cell biology --- Cellular biology --- Cytologists --- Genetic aspects --- Health Workforce --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biomolecules --- Systems biology --- Medicine --- Developmental Biology and Stem Cells. --- Stem Cell Biology. --- Medical Genetics. --- Biomedical Research. --- Research. --- Biological research --- Biomedical research