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Antioncogenes. --- Tumor suppressor proteins. --- Antioncoproteins --- Growth suppressor proteins --- Metastasis suppressor proteins --- Proteins --- Antioncogenes --- Anti-oncogenes --- Cancer suppressor genes --- Emerogenes --- Tumor suppressing genes --- Tumor suppressor genes --- Cancer genes --- Tumor suppressor proteins
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Pathological biochemistry --- Human medicine --- medische biochemie --- biomedische wetenschappen --- geneeskunde --- Tumor suppressor proteins. --- Tumor Suppressor Proteins. --- Antioncoproteins --- Growth suppressor proteins --- Metastasis suppressor proteins --- Proteins --- Antioncogenes --- Growth Suppressor Proteins --- Metastasis Suppressor Proteins --- Proteins, Growth Suppressor --- Proteins, Metastasis Suppressor --- Proteins, Tumor Suppressor --- Genes, Tumor Suppressor --- Tumors --- Carcinomes --- Malalties neoplàstiques --- Neoplàsies --- Neoplasmes --- Patologia --- Càncer --- Feocromocitoma --- Fibromes --- Marcadors tumorals --- Mesotelioma --- Miomes --- Pòlips (Patologia) --- Sarcoïdosi --- Teratoma --- Tumors de parts toves --- Tumors en els animals --- Classificació de tumors --- Oncologia --- Quistos
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Cancer cells --- Growth. --- Cells --- Pathology, Cellular --- Cancer cell growth --- Tumor Suppressor Proteins. --- Apoptosis. --- Apoptosis, Extrinsic Pathway --- Apoptosis, Intrinsic Pathway --- Caspase-Dependent Apoptosis --- Classic Apoptosis --- Classical Apoptosis --- Programmed Cell Death --- Programmed Cell Death, Type I --- Apoptoses, Extrinsic Pathway --- Apoptoses, Intrinsic Pathway --- Apoptosis, Caspase-Dependent --- Apoptosis, Classic --- Apoptosis, Classical --- Caspase Dependent Apoptosis --- Cell Death, Programmed --- Classic Apoptoses --- Extrinsic Pathway Apoptoses --- Extrinsic Pathway Apoptosis --- Intrinsic Pathway Apoptoses --- Intrinsic Pathway Apoptosis --- Necrosis --- Cell Death --- Clonal Deletion --- Superantigens --- Caspases --- Caspase 1 --- In Situ Nick-End Labeling --- Cellular Apoptosis Susceptibility Protein --- Genes, Transgenic, Suicide --- Growth Suppressor Proteins --- Metastasis Suppressor Proteins --- Proteins, Growth Suppressor --- Proteins, Metastasis Suppressor --- Proteins, Tumor Suppressor --- Genes, Tumor Suppressor --- Apoptosi
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The initial identification of the Adenomatous polyposis coli (Apc) gene as the site of mutations in familial adenomatous polyposis (FA P) was described in 1992. A causal relationship between Apc mutations and intestinal tract tumours was confirmed three years later with the establishment of the Min mouse model. These mice are heterozygous for Apc and develop numerous intestinal tumours that mimic FA P. Subsequently, Apc has emerged as the most commonly mutated gene in colorectal cancer with reports varying between 50-80 per cent of sporadic tumours carrying such mutations. The search for how m
Adenomatous Polyposis Coli Protein. --- Adenomatous Polyposis Coli. --- Colon (Anatomy) -- Cancer. --- Colorectal Neoplasms -- Metabolism. --- Genes, APC. --- Tumor suppressor proteins. --- Colon (Anatomy) --- Tumor suppressor proteins --- Adenomatous Polyposis Coli --- Colorectal Neoplasms --- Genes, APC --- Metabolism --- Adenomatous Polyposis Coli Protein --- Intestinal Polyposis --- Intestinal Neoplasms --- Colonic Neoplasms --- Neoplastic Syndromes, Hereditary --- Colonic Diseases --- Metabolic Phenomena --- Cytoskeletal Proteins --- Genes, Tumor Suppressor --- Tumor Suppressor Proteins --- Rectal Diseases --- Adenomatous Polyps --- Proteins --- Neoplasm Proteins --- Intestinal Diseases --- Neoplasms --- Genes, Neoplasm --- Phenomena and Processes --- Gastrointestinal Neoplasms --- Genes, Recessive --- Adenoma --- Genetic Diseases, Inborn --- Gastrointestinal Diseases --- Digestive System Neoplasms --- Genes --- Diseases --- Neoplasms, Glandular and Epithelial --- Congenital, Hereditary, and Neonatal Diseases and Abnormalities --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Digestive System Diseases --- Genome Components --- Neoplasms by Site --- Neoplasms by Histologic Type --- Genome --- Genetic Structures --- Genetic Phenomena --- Oncology --- Medicine --- Health & Biological Sciences --- Cancer --- Cancer. --- Antioncoproteins --- Growth suppressor proteins --- Metastasis suppressor proteins --- Colon cancer --- Colorectal cancer --- Medicine. --- Biomedicine. --- Biomedicine general. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Antioncogenes --- Health Workforce --- Biomedicine, general.
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The cell cycle is tightly regulated on many different levels to ensure properly controlled proliferation. Deregulation of cell cycle regulation is a hallmark of cancer. In this book, many aspects of cell cycle regulation are discussed, which include G1, S, M phase control, ubiquitin-mediated degradation, DNA damage response, mitotic spindle checkpoint, the centrosome cycle, Retinoblastoma protein family, the Myc oncogene, and mouse models for tumor suppressors, cyclin-dependent kinases, and meiosis. These chapters written by experts provide an updated view on how the cell cycle is regulated in vivo and about the involvement of cell cycle regulators in cancer.
Cell Cycle. --- Cell Cycle Proteins --- Cell Proliferation. --- Tumor Suppressor Proteins. --- Cellular control mechanisms. --- Cell cycle --- Régulation cellulaire --- Cycle cellulaire --- physiology. --- Regulation. --- Régulation --- Tumor Suppressor Proteins --- Cell Cycle --- Cell Proliferation --- Neoplasm Proteins --- Cell Physiological Processes --- Proteins --- Cell Growth Processes --- Amino Acids, Peptides, and Proteins --- Growth --- Cell Physiological Phenomena --- Growth and Development --- Chemicals and Drugs --- Phenomena and Processes --- Physiological Processes --- Physiological Phenomena --- Cytology --- Biology --- Health & Biological Sciences --- Development and Growth --- Cell Physiological Phenomenon --- Cell Physiological Process --- Physiology, Cell --- Cell Physiology --- Phenomena, Cell Physiological --- Phenomenon, Cell Physiological --- Physiological Process, Cell --- Physiological Processes, Cell --- Process, Cell Physiological --- Processes, Cell Physiological --- Cells --- Physiological Concepts --- Physiological Phenomenon --- Physiological Process --- Concept, Physiological --- Concepts, Physiological --- Phenomena, Physiological --- Phenomenas, Physiological --- Phenomenon, Physiological --- Physiological Concept --- Process, Physiological --- Processes, Physiological --- Processes, Cell Growth --- Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- Proteins, Neoplasm --- Cell Division Cycle Proteins --- Cell-Cycle Regulatory Proteins --- cdc Proteins --- Cell Cycle Regulatory Proteins --- Cell Multiplication --- Cell Number Growth --- Cell Growth in Number --- Cellular Proliferation --- Growth, Cell Number --- Multiplication, Cell --- Number Growth, Cell --- Proliferation, Cell --- Proliferation, Cellular --- Cell Division Cycle --- Cell Cycles --- Cell Division Cycles --- Cycle, Cell --- Cycle, Cell Division --- Cycles, Cell --- Cycles, Cell Division --- Division Cycle, Cell --- Division Cycles, Cell --- Growth Suppressor Proteins --- Metastasis Suppressor Proteins --- Proteins, Growth Suppressor --- Proteins, Metastasis Suppressor --- Proteins, Tumor Suppressor --- physiology --- Life sciences. --- Cancer research. --- Biochemistry. --- Cell biology. --- Life Sciences. --- Cell Biology. --- Cancer Research. --- Biochemistry, general. --- Cytology. --- Oncology. --- Tumors --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Cell biology --- Cellular biology --- Cytologists --- Composition --- Cancer research
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