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"The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and make important strides in treatment. Genomics and high-throughput technologies have illuminated the complexity of cancer and the facility with which cancers adapt during their natural history. The field is evolving rapidly with new discoveries and new drugs reported monthly. This book is a timely foundation for understanding in context the origins of molecular oncology and its future directions. The content reviews available technologies for the analysis of cancer tissues and genes; summaries of key oncogenic pathways from a molecular perspective; the technologies, pathways and targeted therapies of a wide range of human malignancies; and new pharmacologic therapies that have a common mechanistic target"-- "This book was conceived more than five years before its publication date. It was intended to provide a resource that summarized technology, biochemistry, molecular pathophysiology, and targeted therapeutics. As contributors were being recruited and chapters written the field that was being described changed at an accelerating pace. It is a tribute to scientific progress that volumes like this one are out-of-date as they are published, but books like this are not meant to contain the most current laboratory discovery or report the most recent FDA approval"--

Cancer --- Tumor markers. --- Carcinogenesis. --- Marqueurs tumoraux --- Cancérogenèse --- Molecular aspects. --- Aspect moléculaire

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Neoplasms --- Biomarkers, Tumor --- Cancer --- Tumor markers --- Marqueurs tumoraux --- diagnosis. --- genetics. --- therapeutic use. --- Genetic aspects. --- Diagnosis. --- Diagnostic use. --- Aspect génétique --- Diagnostic --- Utilisation diagnostique

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Biological markers (Oncology) --- Cancer markers --- Markers [Tumor ] --- Marqueurs tumoraux --- Tellers [Tumor] --- Tumeurs--Marqueurs --- Tumor associated markers --- Tumor markers --- Tumortellers --- Blood --- Molecular diagnosis --- Nucleic acids --- Tumor markers. --- Analysis. --- Analysis --- Congresses

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Management information systems --- Information technology --- Mobile computing --- Wireless communication systems --- Systèmes d'information de gestion --- Technologie de l'information --- Informatique mobile --- Transmission sans fil --- Periodicals. --- Périodiques --- Mobile communication systems --- Mobile commerce --- Computer networks --- Informatique mobile. --- Radiocommunications mobiles. --- Commerce mobile. --- Réseaux d'ordinateurs. --- Computer networks. --- Mobile commerce. --- Mobile communication systems. --- Mobile computing. --- Information Technology --- Mathematical Sciences --- Mobile Computing --- Applied Mathematics --- mobile computing --- tablets --- cellular phone --- mobile telecommunications --- mobile network --- mobile information systems --- M-business --- M-commerce --- Mobile business --- Mobile payments --- Electronic commerce --- Electronic funds transfers --- Electronic data processing --- Context-aware computing --- Portable computers --- Vehicles --- Vehicular communication systems --- Radio --- Communication systems, Computer --- Computer communication systems --- Data networks, Computer --- ECNs (Electronic communication networks) --- Electronic communication networks --- Networks, Computer --- Teleprocessing networks --- Data transmission systems --- Digital communications --- Electronic systems --- Information networks --- Telecommunication --- Cyberinfrastructure --- Network computers --- Communication systems --- Distributed processing --- tablet computers --- cellular telephones --- Tumor Markers, Biological --- Biochemical Tumor Markers --- Biological Tumor Marker --- Biological Tumor Markers --- Biomarkers, Cancer --- Marker, Biochemical Tumor --- Marker, Biologic Tumor --- Marker, Biological Tumor --- Marker, Neoplasm Metabolite --- Marker, Tumor Metabolite --- Markers, Biochemical Tumor --- Markers, Biological Tumor --- Markers, Neoplasm Metabolite --- Markers, Tumor Metabolite --- Metabolite Markers, Tumor --- Neoplasm Metabolite Markers --- Tumor Markers, Biologic --- Tumor Metabolite Marker --- Carcinogen Markers --- Markers, Tumor --- Metabolite Markers, Neoplasm --- Tumor Markers, Biochemical --- Biochemical Tumor Marker --- Biologic Tumor Marker --- Biologic Tumor Markers --- Cancer Biomarkers --- Markers, Biologic Tumor --- Markers, Carcinogen --- Metabolite Marker, Neoplasm --- Metabolite Marker, Tumor --- Neoplasm Metabolite Marker --- Tumor Biomarkers --- Tumor Marker, Biochemical --- Tumor Marker, Biologic --- Tumor Marker, Biological --- Tumor Markers --- Tumor Metabolite Markers --- Neoplasm Proteins --- Computer Science --- Cancer Biomarker --- Tumor Biomarker --- Tumor Marker --- Biomarker, Cancer --- Biomarker, Tumor --- Marker, Tumor --- Tumor markers. --- Biomarkers, Tumor --- Computer Communication Networks --- Radiocommunications mobiles --- Commerce mobile --- Réseaux d'ordinateurs --- Marqueurs tumoraux. --- Computer Network Management --- Databases, Distributed --- Distributed Systems --- Extranets --- Intranets --- Network Communication Protocols --- Telecommunication Networks --- Communication Network, Computer --- Communication Networks, Computer --- Communication Protocol, Network --- Communication Protocols, Network --- Computer Communication Network --- Database, Distributed --- Distributed Database --- Distributed Databases --- Distributed System --- Extranet --- Intranet --- Management, Computer Network --- Network Communication Protocol --- Network Management, Computer --- Network, Computer Communication --- Network, Telecommunication --- Networks, Computer Communication --- Networks, Telecommunication --- Protocol, Network Communication --- Protocols, Network Communication --- System, Distributed --- Systems, Distributed --- Telecommunication Network --- Telecommunications --- Education, Distance --- Biological markers (Oncology) --- Cancer markers --- Tumor associated markers --- Biochemical markers --- Tumors --- Biomarkers, Tumor. --- Sistemes de comunicacions mòbils --- Computer Communication Networks.