Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Tropical zones --- Tropical zones --- Traditional farming --- Traditional farming --- Modernization --- Modernization --- Fertilizer application --- Fertilizer application --- Yield increases --- Yield increases --- Crops --- Crops --- Plant production --- Plant production --- Plant propagation --- Plant propagation --- Sexual reproduction --- Sexual reproduction --- Vegetative propagation --- Vegetative propagation --- extension activities --- extension activities --- Developing countries --- Developing countries --- Plant breeding --- Plant breeding --- UNESCO --- UNESCO --- Traditional techniques --- Mab --- Traditional techniques --- Mab

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Monoclonal antibodies (mAbs) are among the most specialised molecules for the recognition and capture of specific analytes. Hundreds of thousands of mAbs have been generated for a large number of different antigens with increasing affinity and specificity and are available for the most diverse purposes. Many of them have been validated as irreplaceable agents for diagnosis and therapy or as unique reagents for research. Others have been developed using emerging technologies that avoid the need for animal immunisation. This short book strives to gather the perspective view of the various contributing authors and to survey the new strategic assets adopted to generate novel monoclonal antibodies or surrogates, such as Fab, Fab2, ScFv and nanobodies, which have an increasing impact in biomedicine as therapeutic or diagnostic assets in various diseases.

Research & information: general --- Biology, life sciences --- PRAME --- mAb --- bio-layer interferometry --- epitope identification --- monoclonal antibody --- free radical --- protein aggregation --- oxidation --- excipient --- foot-and-mouth disease virus --- type O --- type A --- phage display --- antibody --- competitive ELISA --- atherosclerosis --- nano-emulsion --- magnetic resonance imaging --- stealth --- human antibody --- C. auris --- candidiasis --- multidrug resistance --- monoclonal antibodies --- universal antibodies --- cell wall --- passive immunization --- cell-based panning --- semi-automated cell panning --- FGFR3-specific antibody --- PRAME --- mAb --- bio-layer interferometry --- epitope identification --- monoclonal antibody --- free radical --- protein aggregation --- oxidation --- excipient --- foot-and-mouth disease virus --- type O --- type A --- phage display --- antibody --- competitive ELISA --- atherosclerosis --- nano-emulsion --- magnetic resonance imaging --- stealth --- human antibody --- C. auris --- candidiasis --- multidrug resistance --- monoclonal antibodies --- universal antibodies --- cell wall --- passive immunization --- cell-based panning --- semi-automated cell panning --- FGFR3-specific antibody

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Forêt tropicale --- Tropical forests --- Ressource alimentaire --- Food resources --- Nutrition humaine --- human nutrition --- Cueillette --- Picking --- Comportement alimentaire --- Feeding habits --- Environnement socioculturel --- sociocultural environment --- Femme --- women --- Régime alimentaire --- diet --- Recherche de nourriture --- Foraging --- Chasse --- Hunting --- Agriculture de subsistance --- Subsistence farming --- Plante médicinale --- Drug plants --- Nutrition --- nutrition --- UNESCO --- Afrique --- Africa --- ETH Ethnobotany & Economic botany --- ethnobotany & economic botany --- food plants --- rain forests --- useful plants --- nutrition. --- Ethnologie --- Mab --- Aka pygmies --- Lobaye --- Lake tumba region --- Ntomba --- Yassa --- Tabou alimentaire

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

SCIENCE --- Earth Sciences / Geology --- Volcanic hazard analysis --- Dynamic & Structural Geology --- Geology --- Earth & Environmental Sciences --- Rainier, Mount (Wash.) --- Hazard analysis, Volcanic --- Volcanic eruption hazard analysis --- Volcanic hazard assessment --- Volcanoes --- Hazard analysis --- Harrison, Mount (Wash.) --- Lincoln, Mount (Pierce County, Wash.) --- Mount Harrison (Wash.) --- Mount Lincoln (Pierce County, Wash.) --- Mount Rainier (Wash.) --- Mount Tacoma (Wash.) --- Mount Tahoma (Wash.) --- Mount William Henry Harrison (Wash.) --- Puak-cokc (Wash.) --- Ta-co-be (Wash.) --- Ta-co-pe (Wash.) --- Ta-ho-ma (Wash.) --- Tacoba (Wash.) --- Tacobet (Wash.) --- Tacoma, Mount (Wash.) --- Tah-ho-mab (Wash.) --- Tah-o-mah (Wash.) --- Tahoma, Mount (Wash.) --- Ttiwouk (Wash.) --- Tu-ahku (Wash.) --- William Henry Harrison, Mount (Wash.) --- Volcanic activity prediction --- Cascade Range

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This Special Issue of Cells on “Insulin-Like Growth Factors in Development, Cancers and Aging” provides a collection of modern articles dealing with the role of insulin-like growth factors (IGF1) in cancer biology, aging and development. Featured articles explore basic and clinical aspects of the IGF1 system, including post-genomic analyses as well as novel approaches to target the IGF1 receptor (IGF1R) in oncology. The present Special Issue highlights some of the most important topics in the broad area of IGF research, including the role of IGF1 in aging and longevity, attempts to target the IGF1 axis in oncology, the role of IGF-binding proteins, structural aspects of IGF-II, etc. We trust that this assembly of articles will be of great help to students, basic researchers and practitioners.

Research & information: general --- Biology, life sciences --- IGF-I --- IGF-II --- insulin --- IGF-IR --- IRs --- tyrosine kinase receptor --- GPCRs --- hybrids --- phosphorylation --- G-proteins --- β-arrestins --- functional RTK/GPCR hybrid --- nuclear translocation --- IGF-I receptor --- signaling --- targeted therapeutics --- IGF-Trap --- IGF system --- IGFBP-3 --- IGFBP-3R --- TMEM219 --- anti-tumor --- anti-metastatic --- agonists --- mAb therapy --- IGF-1 --- IGFBP-1 --- older adults --- longevity --- health-span --- age-related disease --- cognitive impairment --- diabetes --- mitochondria --- growth hormone --- insulin-like growth factor-1 --- aging --- oxidative stress --- senescence --- longitudinal study --- IGFBP --- mouse models --- skeletal muscle --- MSCs --- myogenesis --- glucose regulated protein (GRP) 94 --- insulin-like growth factor --- obligate chaperone --- hypertrophy --- atrophy --- cachexia --- muscle regeneration --- autophagy --- IGF-1R --- insulin receptor --- IR-A --- structural studies --- receptor activation --- IGF-I --- IGF-II --- insulin --- IGF-IR --- IRs --- tyrosine kinase receptor --- GPCRs --- hybrids --- phosphorylation --- G-proteins --- β-arrestins --- functional RTK/GPCR hybrid --- nuclear translocation --- IGF-I receptor --- signaling --- targeted therapeutics --- IGF-Trap --- IGF system --- IGFBP-3 --- IGFBP-3R --- TMEM219 --- anti-tumor --- anti-metastatic --- agonists --- mAb therapy --- IGF-1 --- IGFBP-1 --- older adults --- longevity --- health-span --- age-related disease --- cognitive impairment --- diabetes --- mitochondria --- growth hormone --- insulin-like growth factor-1 --- aging --- oxidative stress --- senescence --- longitudinal study --- IGFBP --- mouse models --- skeletal muscle --- MSCs --- myogenesis --- glucose regulated protein (GRP) 94 --- insulin-like growth factor --- obligate chaperone --- hypertrophy --- atrophy --- cachexia --- muscle regeneration --- autophagy --- IGF-1R --- insulin receptor --- IR-A --- structural studies --- receptor activation