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Gas chromatography continues to be one of the most widely used analytical techniques, since its applications today expand into fields such as biomarker research or metabolomics. This new practical textbook enables the reader to make full use of gas chromatography. Essential fundamentals and their implications for the practical work at the instrument are provided, as well as details on the instrumentation such as inlet systems, columns and detectors. Specialized techniques from all aspects of GC are introduced ranging from sample preparation, solvent-free injection techniques, and pyrolysis GC, to separation including fast GC and comprehensive GCxGC and finally detection, such as GC-MS and element-specific detection. Various fields of application such as enantiomer, food, flavor and fragrance analysis, physicochemical measurements, forensic toxicology, and clinical analysis are discussed as well as cutting-edge application in metabolomics is covered. About the Editors: Katja Dettmer-Wilde is Principal Investigator heading the mass spectrometry - metabolomics group at the Institute of Functional Genomics, University of Regensburg, Germany. She studied chemistry at the University of Leipzig and got her PhD with Werner Engewald working on the analysis of volatile organic compounds by GC-MS. Since her postdoctoral studies at the University of California Davis she has been focusing on hyphenated separation techniques in metabolomics. Werner Engewald is professor emeritus of the University of Leipzig, Germany. He is one of the leading gas chromatographers worldwide and has made substantial contributions towards the development of this technique. He regularly gives courses for GC users. He was awarded the Martin gold medal of the Chromatographic Society in 2002 and the Clemens-Winkler-Medal of the Division of Analytical Chemistry of the German Chemical Society in 2009.  .

Fysicochemical separation methods --- Chemistry --- Toxicology --- Pharmacology. Therapy --- Environmental protection. Environmental technology --- MS GC (massaspectrometrie gaschromatografie) --- klinische chemie --- farmacologie --- genomics --- chemie --- multimedia --- toxicologie --- milieutechnologie --- chromatografie --- GC (gas chromatography) --- oplosmiddelen

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Understanding Mass Spectra: A Basic Approach, Second Edition combines coverage of the principles underlying mass spectral analysis with clear guidelines on how to apply them in a laboratory setting. Completely revised from the first edition, an updated and unified approach to mass spectral interpretation emphasizes the application of basic principles from undergraduate organic, analytical, and physical chemistry courses. 
A detailed overview of theory and instrumentation, this useful guide contains step-by-step descriptions of interpretative strategies and convenient lists and tables detailing the information needed to solve unknowns. Other features include real-world case studies and examples, skill-building problems with clearly explained answers, and easy-to-follow explanations of the important mathematical derivations.


Mass spectrometry. --- Physicochemistry --- Spectrometric and optical chemical analysis --- Fysicochemical separation methods --- Organic spectroscopy --- Organic chemistry --- organic chemistry --- spectrometry --- gas chromatography --- isotopes --- gamma ray spectrometry --- aromatic hydrocarbon --- massaspectrometrie --- MS GC (massaspectrometrie gaschromatografie) --- isotopen --- massaspectroscopie --- organische chemie --- massaspectra --- siliconen --- GC (gas chromatography) --- fysicochemie --- spectrometrie

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This highly successful textbook, acclaimed for its comprehensiveness,  accuracy, and its many excellent illustrations and photographs now comes in its second edition. Completely revised and substantially extended it  offers:

New chapter on **Tandem Mass Spectrometry** covering instrumentation, methods for ion activation (CID, ECD, ETD, IRMPD), and applications

New chapter on **Ambient Mass Spectrometry** (DART, DESI, and more)

New chapter on **Inorganic Mass Spectrometry** including element speciation and imaging

**Learning Objectives** for all chapters

**Advanced Instrumentation** such as orbitraps, linear ion traps, tandem TOFs, FT-ICR and the highly variable hybrid instruments

Updated **Problems and Solutions website** (www.ms-textbook.com)

 ***Jürgen H. Gross*** provides in-depth explanations of concepts, methods, and techniques. Students and professionals alike are guided step-by-step from the basics to the successful application of mass spectrometry. Starting from the very principles of gas-phase ion chemistry, isotopic composition, and accurate mass, ***Jürgen H. Gross*** leads through the design of all types of mass analyzers and ionization methods to mass spectral interpretation and coupling techniques. His book offers a balanced mixture of practice-oriented information and theoretical background supported by a wealth of references. 

Keywords 

Analytical Chemistry - CID, IRMPD, ECD, ETD - Chemical Ionization - DART, DESI, DAPCI - Electron Ionization - Electrospray Ionization - Fast Atom Bombardment - Field Desorption - Field Ionization - Inorganic Mass Spectrometry - Isotope Ratio - LIFDI - MALDI - Mass Spectrometry - TOF/TOF - Tandem Mass Spectrometry - Textbook


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