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DNA Methylation --- Neoplasms --- Micronutrients

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Vitamin C. --- Micronutrients.

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Obesity is a world disease that does not stop evolving at the moment, and has an impact on the everyday life of those who suffer from it. A method to fight against this condition is the bariatric surgery. This type of intervention, which modifies the digestive tract of the patient, is going to allow him to !ose weight and to improve some of his comorbidity. Carried out in very specific conditions, it also contains disadvantages. So, besides the risks connected to the surgical operation strictly speaking, the obesity's surgery is going to disrupt the assimilation of medicine and micronutrients.What physiological and medicinal modifications is the bariatric surgery going to engender? What medicine to avoid or which formulations to favor? And what about micronutritional deficiencies? A fan of questions, which will be approached in particular during this report... L'obésité est une maladie mondiale qui ne cesse d'évoluer à l'heure actuelle, et a un impact sur la vie quotidienne de ceux qui en souffrent. Une méthode pour lutter contre cette condition est la chirurgie bariatrique. Ce type d'intervention, qui modifie le tractus digestif du patient, va lui permettre de perdre du poids et d'améliorer certaines de ses comorbidités. Réalisée dans des conditions bien spécifiques, elle comporte aussi des inconvénients. Ainsi, en plus des risques liés à l'intervention chirurgicale à proprement parlé, la chirurgie de l'obésité va perturber l'assimilation des médicaments et des micronutriments. Quelles modifications physiologiques et médicamenteuses la chirurgie bariatrique va-t-elle engendrer ? Quels médicaments éviter ou quelles formulations privilégier ? Et qu'en est-il des carences micro nutritionnelles ? Un éventail de questions qui seront notamment abordées au cours de ce mémoire...

Bariatric Surgery --- Micronutrients --- Drug Interactions

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World Nutrition --- Micronutrients. --- Nutrition Disorders --- prevention & control.

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Biochimie --- Biochimie clinique --- Biochemistry --- Molecular biology --- Cell biology --- Disease --- Xenobiotics --- Micronutrients --- Gene expression regulation --- physiopathology --- metabolism