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Avian leukosis. --- Marek's disease. --- Veterinary virology --- Technique.

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Marek's disease virus (MDV) is a herpesvirus which causes a lymphoproliferative disorder of the domestic chicken worldwide. The serious economical problem caused by MDV was mostly solved by development of an effective vaccine against MDV. The development of live vaccines against the disease is remarkable as it has led to the first example of a commercially available vaccine against cancer as well as against diseases caused by herpesviruses. This volume gives an overview on many aspects of MDV research and summarizes recent advances in the field. The topics include the history, biology and molecular biology of MDV, pathogenesis, vaccinal immunity, immune response, genetic resistance and development of recombinant polyvalent vaccines. It is hoped that this volume will make an important contribution towards the control of infectious diseases.

Acute leukosis of poultry --- Avian lymphomatosis --- Fowl paralysis --- Lymphomatosis [Avian ] --- Maladie de Marek --- Marek [Maladie de ] --- Marek's disease --- Neurolymphomatosis gallinarum --- Ziekte van Marek --- MAREK'S DISEASE --- Herpesvirus 2 --- Poultry --- Gallid --- MAREK'S DISEASE. --- Poultry. --- Gallid. --- Virology. --- Immunology. --- Molecular biology. --- Cancer research. --- Molecular Medicine. --- Cancer Research. --- Cancer research --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Immunobiology --- Life sciences --- Serology --- Microbiology

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A Special Issue in memory of Randall J. Cohrs, Ph.D. Topics include original research reports on a variety of viruses as well as reviews and commentaries on Randy’s contributions to many investigations.

Research & information: general --- Biology, life sciences --- varicella-zoster virus --- Oka strain --- human herpesvirus 6 --- human herpesvirus 7 --- corticosteroids --- serious adverse event --- herpes zoster --- IL-6 --- IL-10 --- innate immunity --- VLT --- VLT-ORF63 --- CRISPR/Cas9 --- BAC mutagenesis --- flavivirus --- SARS-CoV-2 --- pandemic preparedness --- host–virus interactions --- prion --- vaccines --- interferon lambda --- virus --- herpes simplex virus type 1 --- herpes simplex virus type 2 --- neonatal herpesvirus infection --- HSV UL6 --- herpesvirus encephalitis --- herpesvirus hepatitis --- acyclovir --- HerpeSelect test --- viral sequencing --- HELLP syndrome --- lipids --- dengue virus --- acyl-CoA --- acyl-CoA thioesterase --- fatty acids --- membranes --- rheostat --- fatty acyl-CoA --- Marek’s disease virus --- live-cell genome visualization --- lytic replication --- T cells --- latency --- genome integration --- TetO/TetR system --- varicella zoster virus --- reactivation --- genome cleavage --- AAV --- antiviral therapies --- HSV-1 --- cornea --- trigeminal ganglia --- interferon-γ --- interferon stimulatory genes --- TRIM21 --- HSV --- EBV --- KSHV --- MHV68 --- PIC --- transcription --- productive elongation --- mRNA --- rRNA --- tRNA --- herpes --- viral reactivation --- spaceflight --- dermatitis --- stress --- immune depression --- antiviral drugs --- bacterial artificial chromosome --- luciferase --- bioluminescence imaging --- skin organ culture --- humanized mice --- β-Coronavirus --- mouse hepatitis virus-A59/MHV-A59 --- mouse hepatitis virus-2/MHV2 spike protein --- fusion peptide/FP --- cell-to-cell fusion (fusogenicity) --- neuropathogenesis --- hepatitis --- demyelination --- structural rigidity --- simian varicella virus --- herpesvirus --- varicella --- VZV --- neuro-attenuated --- ORF7 --- vaccine --- n/a --- antiviral --- COVID-19 --- drug discovery --- coronavirus --- spike protein --- Mpro --- RdRp --- PLpro --- skin --- epidermis --- keratinocytes --- epidermal differentiation --- cutaneous blistering lesions --- keratins --- autophagy --- immunity --- human neuron culture --- non-coding RNA --- CD8 T cell --- T-cell epitope --- NK cell --- KIR3DL1 --- HLA-B*57:01 --- herpes simplex virus --- zoster --- skin pathogenesis --- HSV-2 --- neurons --- cell culture --- varicella-zoster --- gene expression --- ganglion --- autopsy --- saliva --- salivary VZV DNA --- dengue viruses --- Aedes aegypti --- adaptive mutation --- host-virus interactions --- Marek's disease virus