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Bioelectric sensors are unique diagnostic principles and technologies. Although they share many traits with electrochemical sensors, especially regarding the common features of instrumentation, they are focused on the measurement of the electric properties of biorecognition elements as a reflection of cellular, biological, and biomolecular functions in a rapid, very sensitive, and often non-invasive manner. Bioelectric sensors offer a plethora of options in terms both of assay targets (molecules, cells, organs, and organisms) and methodological approaches (e.g., potentiometry, impedance spectrometry, and patch-clamp electrophysiology). Irrespective of the method of choice, “bioelectric profiling” is being rapidly established as a superior concept for a number of applications, including in vitro toxicity, signal transduction, real-time medical diagnostics, environmental risk assessment, and drug development. This Special Issue is the first that is exclusively dedicated to the advanced and emerging concepts and technologies of bioelectric sensors. Topics include, but are not restricted to, bioelectric sensors for single cell analysis, electrophysiological olfactory and volatile organic compounds sensors, impedimetric biosensors, microbial fuel cell biosensors, and implantable autonomous bioelectric micro- and nano-sensors.

organic optoelectronic device --- pulse meter --- biosensor --- Bluetooth low energy (BLE) --- photoplethysmogram (PPG) --- chronic wounds --- electrical stimulation --- direct microcurrent --- non-invasive --- pressure ulcer --- wireless technology --- biochips --- impedance spectroscopy --- electrical equivalent circuit --- biomaterial --- Lysinibacillus sphaericus JG-A12 --- anticancer therapeutic strategies --- apoptosis --- bioelectric --- 5-fluorouracil --- HeLa cell line --- superoxide --- cell immobilization --- 3D-printed well --- bioelectric profiling --- impedance analysis --- real-time measurements --- electrochemical biosensors --- SWCNT --- point-of-care diagnostics --- label-free biosensors --- ELISA --- carbon nanotubes --- bovine serum albumin --- pacemaker --- threat modeling --- internet of things (IoT) medical devices --- vulnerabilities --- n/a

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Metal ions are fundamental elements for the maintenance of the lifespan of plants, animals and humans. Their substantial role in biological systems was recognized a long time ago. They are essential for the maintenance of life and their absence can cause growth disorders, severe malfunction, carcinogenesis or death. They are protagonists as macro- or microelements in several structural and functional roles, participating in many bio-chemical reactions, and arise in several forms. They participate in intra- and intercellular communications, in maintaining electrical charges and osmotic pressure, in photosynthesis and electron transfer processes, in the maintenance of pairing, stacking and the stability of nucleotide bases and also in the regulation of DNA transcription. They contribute to the proper functioning of nerve cells, muscle cells, the brain and the heart, the transport of oxygen and to many other biological processes up to the point that we cannot even imagine a life without metals. In this book, the papers published in the Special Issue “The Role of Metal Ions in Biology, Biochemistry and Medicine” are summarized, providing a picture of metal ion uses in biology, biochemistry and medicine, but also pointing out the toxicity impacts on plants, animals, humans and the environment.

Research & information: general --- aluminium --- chlorophyll fluorescence --- durum wheat --- excitation pressure --- non-photochemical quenching --- photosynthesis --- photoprotection --- photoinhibition --- reactive oxygen species --- triticale --- Cd toxicity --- detoxification mechanism --- photochemical quenching --- photosynthetic heterogeneity --- photoprotective mechanism --- phytoremediation --- plastoquinone pool --- redox state --- spatiotemporal variation --- mercury --- biosorption --- dead cells --- Lysinibacillus sphaericus --- dithizone --- GF-AAS --- EDS-SEM --- adaptive response --- hormetic response --- hydrogen peroxide --- marine angiosperms --- reactive oxygen species (ROS) --- zinc oxide nanoparticles --- titanium dioxide --- nanoparticles --- solubility --- toxicity --- skin --- safety --- bimetallic nanoparticles --- mature leaves --- spatiotemporal heterogeneity --- young leaves --- osteoblasts --- corrosion --- ions --- particles --- osteolysis --- inflammation --- bioimaging --- clary sage --- effective quantum yield (ΦPSΙΙ) --- non-photochemical quenching (NPQ) --- photochemical quenching (qp) --- singlet oxygen (1O2) --- aseptic loosening --- metal ions --- monocytes --- macrophages --- 5-caffeoylquinic acid --- chlorogenic acid --- zinc --- plant phenolic compounds --- oxidative stress --- n/a

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• Reference Manager
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Metal ions are fundamental elements for the maintenance of the lifespan of plants, animals and humans. Their substantial role in biological systems was recognized a long time ago. They are essential for the maintenance of life and their absence can cause growth disorders, severe malfunction, carcinogenesis or death. They are protagonists as macro- or microelements in several structural and functional roles, participating in many bio-chemical reactions, and arise in several forms. They participate in intra- and intercellular communications, in maintaining electrical charges and osmotic pressure, in photosynthesis and electron transfer processes, in the maintenance of pairing, stacking and the stability of nucleotide bases and also in the regulation of DNA transcription. They contribute to the proper functioning of nerve cells, muscle cells, the brain and the heart, the transport of oxygen and to many other biological processes up to the point that we cannot even imagine a life without metals. In this book, the papers published in the Special Issue “The Role of Metal Ions in Biology, Biochemistry and Medicine” are summarized, providing a picture of metal ion uses in biology, biochemistry and medicine, but also pointing out the toxicity impacts on plants, animals, humans and the environment.

Research & information: general --- aluminium --- chlorophyll fluorescence --- durum wheat --- excitation pressure --- non-photochemical quenching --- photosynthesis --- photoprotection --- photoinhibition --- reactive oxygen species --- triticale --- Cd toxicity --- detoxification mechanism --- photochemical quenching --- photosynthetic heterogeneity --- photoprotective mechanism --- phytoremediation --- plastoquinone pool --- redox state --- spatiotemporal variation --- mercury --- biosorption --- dead cells --- Lysinibacillus sphaericus --- dithizone --- GF-AAS --- EDS-SEM --- adaptive response --- hormetic response --- hydrogen peroxide --- marine angiosperms --- reactive oxygen species (ROS) --- zinc oxide nanoparticles --- titanium dioxide --- nanoparticles --- solubility --- toxicity --- skin --- safety --- bimetallic nanoparticles --- mature leaves --- spatiotemporal heterogeneity --- young leaves --- osteoblasts --- corrosion --- ions --- particles --- osteolysis --- inflammation --- bioimaging --- clary sage --- effective quantum yield (ΦPSΙΙ) --- non-photochemical quenching (NPQ) --- photochemical quenching (qp) --- singlet oxygen (1O2) --- aseptic loosening --- metal ions --- monocytes --- macrophages --- 5-caffeoylquinic acid --- chlorogenic acid --- zinc --- plant phenolic compounds --- oxidative stress