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"Primary Liver Cancer: Challenges and Perspectives" presents the recent progress in basic and clinical research in Primary Liver Cancer (PLC) in China and around the world. PLC patients in China make up more than 50% of the total patients worldwide. By contributing to the book, the leading experts in the field of liver cancer in China as well as in the US share with readers their new concepts, practices, and experiences from bench to bed, from population study to individual survey, from molecular search to clinical practice, and from early diagnosis to treatment. The book is intended for researchers in the fields of epidemiology, molecular genetics, cell biology, immunology of HCC and other cancers, and clinical oncology in primary liver cancer. Jianren Gu is a Professor of molecular oncology at the Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine and Academician of Chinese Academy of Engineering.
Carcinoma, Hepatocellular -- diagnosis. --- Liver -- Cancer -- Diagnosis. --- Liver -- Cancer -- Treatment. --- Liver -- Cancer. --- Medicine. --- Cancer research. --- Immunology. --- Oncology. --- Epidemiology. --- Medicine & Public Health. --- Cancer Research. --- Oncology . --- Tumors --- Diseases --- Public health --- Immunobiology --- Life sciences --- Serology --- Cancer research
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The field of liver tumors in children, and in particular hepatoblastoma in infants and young children, has seen tremendous therapeutic advances over recent years. This has been achieved through a much better understanding of the biology of disease, improved diagnostic procedures, refined methods of pretreatment tumor staging, the implementation of highly efficient chemotherapy and surgery, detailed monitoring of toxicity, and careful follow-up strategies. International controlled trials have played a key role in these advances, and many leading figures in the trials are among the editors and authors of this book. Their principal goal in Hepatic Tumors in Children is to provide the reader with a complete update on this complex and rapidly evolving field. All aspects of an impressive success story are covered, disclosing how the outcome of a previously devastating disease has been so dramatically improved. This book will prove essential reading for all who are involved in the care of children with liver tumors.
Liver -- Cancer -- Treatment. --- Liver metastasis -- Treatment. --- Liver Neoplasms -- Therapy. --- Age Groups --- Digestive System Neoplasms --- Liver Diseases --- Neoplasms by Site --- Digestive System Diseases --- Persons --- Diseases --- Named Groups --- Neoplasms --- Liver Neoplasms --- Child --- Medicine --- Health & Biological Sciences --- Oncology --- Liver --- Tumors in children. --- Tumors --- Treatment. --- Pediatric oncology --- Medicine. --- Oncology. --- Pediatrics. --- Medicine & Public Health. --- Children --- Abdomen --- Biliary tract --- Oncology . --- Paediatrics --- Pediatric medicine --- Health and hygiene
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Primary Liver Cancer: Surveillance, Diagnosis and Treatment focuses on the many therapies rapidly evolving to assist with controlling hepatocellular carcinoma as well as emerging technologies to assist in early diagnosis as well as prevention. All chapters are written by experts in their fields and include the most up to date information for diagnosis, treatment, surveillance, epidemiology, staging, recurrence and prevention. This volume will serve as a useful resource for clinical gastroenterologists, hepatologists, oncologists, pathologists, and physicians who treat patients with chronic liver disease and hepatocellular carcinoma.
Liver -- Cancer -- Diagnosis. --- Liver -- Cancer -- Treatment. --- Liver -- Cancer. --- Liver --- Liver Neoplasms --- Adenocarcinoma --- Digestive System Neoplasms --- Carcinoma --- Liver Diseases --- Neoplasms by Site --- Neoplasms, Glandular and Epithelial --- Digestive System Diseases --- Diseases --- Neoplasms by Histologic Type --- Neoplasms --- Carcinoma, Hepatocellular --- Medicine --- Health & Biological Sciences --- Gastroenterology --- Oncology --- Cancer --- Diagnosis --- Treatment --- Oncology. --- Cancer. --- Hepatocellular carcinoma --- Medicine. --- Gastroenterology. --- Hepatology. --- Pathology. --- Primary care (Medicine). --- Medicine & Public Health. --- Primary Care Medicine. --- Tumors --- Clinical medicine. --- Oncology . --- Emergency medicine. --- Medicine, Emergency --- Critical care medicine --- Disaster medicine --- Medical emergencies --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Medicine, Clinical --- Internal medicine --- Digestive organs --- Gastroenterology . --- Primary medical care --- Medical care
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Hepatocellular Carcinoma: Targeted Therapy provides a detailed repository of the latest information regarding HCC epidemiology, diagnosis, imaging, pathology, staging, and treatment options. This volume also provides an up-to-date guide for treatment that explores not only traditional treatments, but newer investigational treatment options including surgical resection, liver transplantation, ablation (radiofrequency, microwave), percutaneous ethanol or acetic acid injection, transarterial chemoembolization (TACE), intra-arterial radiation therapy, and systemic chemotherapy. Heptocellular Carcinoma: Targeted Therapy will be of great value to all health care professionals and trainees worldwide who have an interest in the diagnosis and treatment of HCC, including surgeons, medical oncologists, radiologists, radiation oncologists, and pathologists.
Carcinoma, Hepatocellular -- Diagnosis. --- Carcinoma, Hepatocellular -- therapy. --- Liver -- Cancer -- Diagnosis. --- Liver -- Cancer -- Treatment. --- Liver -- Cancer. --- Liver Neoplasms. --- Liver Neoplasms --- Adenocarcinoma --- Carcinoma --- Digestive System Neoplasms --- Liver Diseases --- Neoplasms by Site --- Neoplasms, Glandular and Epithelial --- Digestive System Diseases --- Diseases --- Neoplasms by Histologic Type --- Neoplasms --- Carcinoma, Hepatocellular --- Medicine --- Surgery & Anesthesiology --- Education --- Health & Biological Sciences --- Social Sciences --- Oncology --- Surgery - General and By Type --- Education, Special Topics --- Liver --- Cancer --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Treatment. --- Surgery. --- Chemotherapy. --- Excision --- Medicine. --- Interventional radiology. --- Gastroenterology. --- Oncology. --- Pathology. --- Surgical oncology. --- Medicine & Public Health. --- Surgical Oncology. --- Interventional Radiology. --- Treatment
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This book provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors. In the past, the therapeutic radiation dose needed to treat a tumoral area has been sufficiently high to produce permanent damage to the nontumoral liver parenchyma. Radioembolization attempts to overcome this problem by combining embolization (intravascular deployment of particles) and brachytherapy (local administration of radiotherapy with the aid of a device, namely the particles themselves). The technique is based on improvements in percutaneous endovascular procedures which have allowed the deployment of small (25-35 µm) microspheres loaded with yttrium-90 that deliver high doses of beta-radiation specifically to the tumoral area. Performance of the procedure demands close familiarity with the hepatic vascular anatomy in order to ensure avoidance of vessels going to other territories. Furthermore, detailed knowledge of liver function, tumor volume, and liver vascular shunting is needed in order to calculate the appropriate therapeutic dose in each particular case. All of these topics are addressed in depth in this book, and initial clinical results are presented, showing that constant local control can be achieved with a reasonably low rate of complications. These promising results may lead to a progressive change in the therapeutic indication for radioembolization, and in some cases it could even become the therapy of choice.
Medicine & Public Health. --- Imaging / Radiology. --- Interventional Radiology. --- Nuclear Medicine. --- Hepatology. --- Oncology. --- Radiotherapy. --- Medicine. --- Medical radiology --- Interventional radiology. --- Nuclear medicine. --- Clinical medicine. --- Médecine --- Radiologie médicale --- Radiologie interventionnelle --- Médecine nucléaire --- Radiothérapie --- Médecine clinique --- Cancérologie --- Brachytherapy -- Methods. --- Embolization, Therapeutic -- Methods. --- Liver -- Cancer -- Treatment. --- Liver Neoplasms -- Radiotherapy. --- Radioisotope brachytherapy. --- Therapeutic embolization. --- Brachytherapy --- Liver Neoplasms --- Embolization, Therapeutic --- Digestive System Neoplasms --- Radiotherapy --- Hemostatic Techniques --- Liver Diseases --- Digestive System Diseases --- Neoplasms by Site --- Therapeutics --- Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Neoplasms --- Radiology, MRI, Ultrasonography & Medical Physics --- Oncology --- Medicine --- Health & Biological Sciences --- Liver --- Cancer --- Treatment. --- Embolotherapy --- Afterloading radiotherapy --- Brachyisotope therapy --- Brachytherapy, Radioisotope --- Implant radiotherapy --- Interstitial radiotherapy --- Radiology. --- Hemostasis, Surgical --- Interventional radiology --- Implants, Artificial --- Radioisotopes --- Therapeutic use --- Radiology, Medical. --- Oncology . --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Therapeutics, Physiological --- Phototherapy --- Tumors --- Medicine, Clinical --- Atomic medicine --- Radioisotopes in medicine --- Radioactive tracers --- Radioactivity --- Radiology, Interventional --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Radiological services --- Physiological effect --- Interventional radiology . --- Gastroenterology --- Radiological physics --- Physics --- Radiation
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This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.
Medicine & Public Health. --- Health Informatics. --- Data Mining and Knowledge Discovery. --- Oncology. --- Hepatology. --- Simulation and Modeling. --- Medicine. --- Medical records --- Clinical medicine. --- Data mining. --- Computer simulation. --- Médecine --- Dossiers médicaux --- Médecine clinique --- Cancérologie --- Exploration de données (Informatique) --- Simulation par ordinateur --- Data processing. --- Informatique --- Liver -- Cancer -- Treatment. --- Liver -- Cancer. --- Medicine --- Health & Biological Sciences --- Medical & Biomedical Informatics --- Liver --- Medicine, Preventive. --- Personalized medicine. --- Cancer. --- Individualized medicine --- Disease prevention --- Diseases --- Prevention of disease --- Preventive medicine --- Hepatocellular carcinoma --- Prevention --- Health informatics. --- Medical care --- Pharmacogenetics --- Pathology --- Preventive health services --- Preventive medicine physicians --- Public health --- Oncology . --- Medicine, Clinical --- Tumors --- Algorithmic knowledge discovery --- Factual data analysis --- KDD (Information retrieval) --- Knowledge discovery in data --- Knowledge discovery in databases --- Mining, Data --- Database searching --- EHR systems --- EHR technology --- EHRs (Electronic health records) --- Electronic health records --- Electronic medical records --- EMR systems --- EMRs (Electronic medical records) --- Information storage and retrieval systems --- Computer modeling --- Computer models --- Modeling, Computer --- Models, Computer --- Simulation, Computer --- Electromechanical analogies --- Mathematical models --- Simulation methods --- Model-integrated computing --- Gastroenterology --- Clinical informatics --- Health informatics --- Medical information science --- Information science --- Data processing
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