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Bovine leukosis --- Melting. --- Melting --- Liposome unilamellaire

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Liposomes. --- Liposomes, Ultra-deformable --- Niosomes --- Transferosomes --- Ultradeformable Liposomes --- Liposome --- Liposome, Ultra-deformable --- Liposome, Ultradeformable --- Liposomes, Ultra deformable --- Liposomes, Ultradeformable --- Niosome --- Transferosome --- Ultra-deformable Liposome --- Ultra-deformable Liposomes --- Ultradeformable Liposome --- Lipid Bilayers --- Liposomes --- Liposomen --- Phospholipid vesicles --- Bilayer lipid membranes --- Cytoplasm --- Phospholipids --- Handbooks, manuals, etc --- Handbooks, manuals, etc. --- Liposomes - Handbooks, manuals, etc

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Filamentous phage (genus Inovirus) infect almost invariably Gram-negative bacteria. They are distinguished from all other bacteriophage not only by morphology, but also by the mode of their assembly, a secretion-like process that does not kill the host. “Classic” Escherichia coli filamentous phage Ff (f1, fd and M13) are used in display technology and bio/nano/technology, whereas filamentous phage in general have been put to use by their bacterial hosts for adaptation to environment, pathogenesis, biofilm formation, horizontal gene transfer and modulating genome stability. Many filamentous phage have a “symbiotic” life style that is often manifested by inability to form plaques, preventing their identification by standard phage-hunting techniques; while the absence or very low sequence conservation between phage infecting different species often complicates their identification through bioinformatics. Nevertheless, the number of discovered filamentous phage is increasing rapidly, along with realization of their significance. “Temperate” filamentous phage whose genomes are integrated into the bacterial chromosome of pathogenic bacteria often modulate virulence of the host. The Vibrio cholerae phage CTXf genome encodes cholera toxin, whereas many filamentous prophage influence virulence without encoding virulence factors. The nature of their effect on the bacterial pathogenicity and overall physiology is the next frontier in understanding intricate relationship between the filamentous phage and their hosts. Phage display has been widely used as a combinatorial technology of choice for discovery of therapeutic antibodies and peptide leads that have been applied in the vaccine design, diagnostics and drug development or targeting over the past thirty years. Virion proteins of filamentous phage are integral membrane proteins prior to assembly; hence they are ideal for display of bacterial surface and secreted proteins. The use of this technology at the scale of microbial community has potential to identify host-interacting proteins of uncultivable or low-represented community members. Recent applications of Ff filamentous phage extend into protein evolution, synthetic biology and nanotechnology. In many applications, phage serves as a monodisperse long-aspect nano-scaffold of well-defined shape. Chemical or chenetic modifications of this scaffold are used to introduce the necessary functionalities, such as fluorescent labels, ligands that target specific proteins, or peptides that promote formation of inorganic or organic nanostructures. We anticipate that the future holds development of new strategies for particle assembly, site-specific multi-functional modifications and improvement of existing modification strategies. These improvements will render the production of filamentous-phage-templated materials safe and affordable, allowing their applications outside of the laboratory.

pathogenic bacteria --- filamentous bacteriophage --- phage display --- Glioblastoma --- Liposome --- Vaccine --- microbial communities --- dip-stick --- chemical modification --- Nanorods

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Drug carriers (Pharmacy) --- Excipients --- Pharmaceutical Preparations. --- Liposomes. --- Macromolecular Substances. --- Pharmaceutical Vehicles. --- -Drug targeting --- -Drugs --- -Liposomes --- -Phospholipid vesicles --- Bilayer lipid membranes --- Cytoplasm --- Phospholipids --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Drugs --- Site-specific drug delivery --- Targeting of drugs --- Target organs (Anatomy) --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Pharmaceutical Vehicle --- Vehicle, Pharmaceutical --- Vehicles, Pharmaceutical --- Macromolecular Complexes --- Macromolecular Compounds --- Macromolecular Compounds and Complexes --- Complexes, Macromolecular --- Compounds, Macromolecular --- Substances, Macromolecular --- Nanostructures --- Liposomes, Ultra-deformable --- Niosomes --- Transferosomes --- Ultradeformable Liposomes --- Liposome --- Liposome, Ultra-deformable --- Liposome, Ultradeformable --- Liposomes, Ultra deformable --- Liposomes, Ultradeformable --- Niosome --- Transferosome --- Ultra-deformable Liposome --- Ultra-deformable Liposomes --- Ultradeformable Liposome --- Lipid Bilayers --- Pharmaceutic Preparations --- Pharmaceutical Products --- Preparations, Pharmaceutical --- Preparations, Pharmaceutic --- Products, Pharmaceutical --- Drug Dosage Calculations --- Congresses --- Effectivness --- -Congresses --- Targeting --- Dosage forms --- Carriers --- Vehicles --- Drug targeting --- Liposomes --- Macromolecular Substances --- Pharmaceutical Preparations --- Pharmaceutical Vehicles --- Phospholipid vesicles --- Effectiveness&delete& --- Drug --- Pharmaceutical --- Pharmaceutical Preparation --- Pharmaceutical Product --- Preparation, Pharmaceutical --- Product, Pharmaceutical --- Effectiveness --- Cells. --- Cells --- Particles --- Pharmaceutical preparations --- Polymers

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This Special Issue provides an update on the state of the art and current trends in polymeric drug-delivery systems specifically designed for improving drug bioavailability. The multiple contributions received further strengthen the role of polymers in modern drug delivery and targeting, illustrating the different approaches possible and unveiling what the future may bring.

Medicine --- Pharmaceutical industries --- cystic fibrosis --- Pseudomonas aeruginosa --- liposomes --- efflux pump inhibitor --- PABN --- aminoglycosides --- macrolides --- poloxamer --- thiourea --- thiolation --- mucoadhesion --- drug release --- in vivo analysis --- in vitro dissolution studies --- S-propargyl-cysteine --- poly(lactic acid) --- endogenous hydrogen sulfide --- water-in-oil-in-water --- rheumatoid arthritis --- chitosan --- drug delivery --- drug absorption --- intestinal assimilation --- oral bioavailability --- nanoemulsions --- micelles --- SEDDS --- zeta potential --- sustained release --- albumin nanoparticle --- MPT0B291 --- high-pressure homogenizer --- histone deacetylase --- calix[8]arenes --- silibinin --- inclusion complexes --- PEGylation --- cytotoxicity --- oromucosal films --- sodium alginate --- nanoparticle drug carriers --- digoxin --- zein --- heart failure --- polymer–liposome complexes --- Pluronic®-poly(acrylic acid) --- Pluronic®-poly(N,N-dimethylaminoethyl methacrylate) --- stimuli-responsive --- intelligent drug delivery systems --- liposome --- polymer --- long circulation --- polymer–lipid conjugates --- targeting --- stimulus-responsive --- antibody --- affinity --- cyclodextrin --- protein therapeutics --- sustained drug delivery --- Nitric oxide --- hydrogel --- wound dressing --- chronic wounds --- glycyrrhetinic acid --- Soluplus® --- solid dispersions --- anti-inflammatory --- biosafety --- bioavailability --- n/a --- polymer-liposome complexes --- polymer-lipid conjugates