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Genetique --- Linkage (genetics) --- Biomathematique

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Until recently, comparative studies have not played a major role in mammalian genetics because there was little to compare. However, this situation has been changed by rapid developments in molecular biology which have revealed details of the genetic structures of a wide range of mammalian species. The resulting flood of information on comparative aspects of mammalian genomes has been scattered across a great many journals and books, and no single source has been available. X-Linked Traits: A Catalog of Loci in Non-Human Mammals presents just such a source for the mammalian X-chromosome. X-Linked Traits will serve as a useful guide for researchers in comparative mammalian genetics, developmental biology, cell biology, and biochemistry, as well as clinical disciplines in human and veterinary medicine.

Mammals --- Sex-linkage (Genetics) --- X chromosome. --- Genetics.

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Linkage (Genetics) --- -Linkage (Genetics) --- -Human genetics --- -Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Genetics --- Heredity --- Chromosomes --- Data processing --- Computer programs --- Human genetics --- Computer programs. --- Data processing. --- -Data processing

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Human genetics --- Linkage (Genetics) --- Liaison génétique --- Liaison génétique --- Génétique humaine

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This detailed new edition collects cutting-edge laboratory protocols, techniques, and applications in use by some of the leading international experts in the broad field of chromosome architecture. The book emphasizes the increasing physiological relevance of chromosome architecture investigation, manifest both through application of more complex bottom-up assays in vitro as well as through maintaining the native physiological context through the investigation of living, functional cells. In addition, the chapters reflect the dramatic improvement in the length scale of precision by utilizing single-molecule approaches, both for imaging the DNA content of chromosome and proteins that bind to DNA as well as using methods that can controllably manipulate single DNA molecules, and the use of advanced computational methods and mathematical analysis is also featured. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Chromosome Architecture: Methods and Protocols, Second Edition is an ideal guide for researchers working in this dynamic area of study.

Chromosomes. --- Chromosome theory --- Cell nuclei --- Crossing over (Genetics) --- Cytotaxonomy --- Genetics --- Karyokinesis --- Linkage (Genetics)