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RNA-ligand interactions
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ISSN: 00766879 ISBN: 0121822184 0121822192 9786611011048 1281011045 008049675X 9786611011031 1281011037 0080496741 9780121822187 9780121822194 Year: 2000 Volume: 317-318 Publisher: San Diego, Calif.: Academic press,

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Abstract

RNA-Ligand Interactions, Part A focuses on structural biology methods. Major topics covered include semisynthetic methodologies (RNA synthetic methods and derivatization of RNA); RNA structure determination (X-ray crystallography, NMR, EM); techniques for monitoring RNA conformation and dynamics (solution methods and electrophoretic and spectroscopic methods); and modeling tertiary structure: Part B, its companion Volume 318 of Methods in Enzymology, focuses on molecular biology methods.The critically acclaimed laboratory standard for more than forty years, Methods

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