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Historic buildings --- Little Kinnakeet Life-Saving and Coast Guard Station (U.S.) --- Cape Hatteras National Seashore (N.C.)

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For centuries sailing vessels crept along the coastline, ready to flee ashore in case of danger or trouble; this worked well until weather or poor sailing drove these ships against an unforgiving coast. Saviors and salvors (often the same people) struggled to rescue both humans and cargo, often with results as tragic for them as for the sailors and passengers. Joseph Francis (b. Boston, Massachusetts, 1801) was an inventor who also had the ability to organize a business to produce his inventions and the salesmanship to sell his products. His metal lifeboats, first

Inventors --- Marine engineering --- Lifeboats --- Lifesaving --- Engineering, Marine --- Marine technology --- Naval engineering --- Engineering --- Naval architecture --- Life-boats --- Surf boats --- Boats and boating --- Life-saving apparatus --- Survival and emergency equipment --- History --- History. --- Equipment and supplies. --- Equipment and supplies --- Francis, Joseph, --- United States. --- Life-Saving Service (U.S.)

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Law of obligations. Law of contract --- Shipping law --- France --- Maritime law --- Salvage --- Quasi contracts --- Droit maritime --- Sauvetage en mer --- Quasi-contrats --- Law and legislation --- Droit --- Assistance in emergencies --- Lifesaving --- Emergency assistance --- Failure to assist in emergencies --- Emergencies --- Bystander effect --- Life-saving --- Rescue work --- Assistance in emergencies - Law and legislation - France --- Lifesaving - France --- Maritime law - France

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Trauma is still a leading cause of death in patients below 40 years of age. Clinical management of severely injured patients is challenging in all phases of treatment during the clinical course. Numerous factors, such as injury severity, injury pattern, patient characteristics and trauma system, affect the decision-making process in our patients. After the successful initial management of an unstable multiply injured patient, secondary definitive surgeries and reconstructions may have a risk for further systemic complications and the deterioration of the patient’s physiology. A “Safe Definitive Surgery” (SDS) concept considers the dynamics of the clinical course (prehospital, operations, complications, etc.) and the patient’s physiology. Due to the repeated re-evaluation and assessment of the patient’s clinical course, dynamics and adaptation of the treatment strategy, the safe management of polytraumatized patients is possible. Many unanswered questions still exist and need to be addressed in future studies: Which patients profit by the damage control strategy and which do not? When is it best to start with the definitive fixation of fractures in multiply injured patients? How can one improve the quality of life in polytraumatized patients? What are the strategies in elderly severely injured patients? With this Special Issue, we would like to stimulate research in the field of polytrauma in order to shed light on the above-mentioned questions

Medicine --- pelvic ring fracture --- PCCD --- position --- associated injuries --- geriatric trauma --- scoring --- polytrauma --- ISS --- AIS --- geriatric patients --- orthogeriatric --- E-bike injuries --- outcome --- injury pattern comparison --- traumatic injury --- reactive oxygen species --- phagocytosis --- CD14 --- CD16 --- CD62L --- fMLP --- PMA --- emergency surgery --- trauma team competence --- trauma system --- life-saving intervention --- trauma --- non-invasive external pelvic stabilizers --- bleeding --- pelvic fractures --- post mortem analysis --- biomechanical force --- pneumatic pelvic sling VBM® --- T-POD® --- cloth sling --- SAM Sling® --- trauma victims --- prehospital death --- Injury Severity Score (ISS) --- hemorrhage --- shock --- resuscitation --- coagulopathy --- oxygen transport --- endotheliopathy --- microcirculation --- macrocirculation --- orthopaedic trauma --- nutritional deficiencies --- vitamins --- lower extremity --- wound complications --- nutrition wound healing --- platelets --- immune system --- posttraumatic organ failure --- posttraumatic lung dysfunction --- posttraumatic hyperinflammation --- I-FABP --- biomarker --- intestinal damage --- hemorrhagic shock --- major trauma --- pelvic ring fracture --- PCCD --- position --- associated injuries --- geriatric trauma --- scoring --- polytrauma --- ISS --- AIS --- geriatric patients --- orthogeriatric --- E-bike injuries --- outcome --- injury pattern comparison --- traumatic injury --- reactive oxygen species --- phagocytosis --- CD14 --- CD16 --- CD62L --- fMLP --- PMA --- emergency surgery --- trauma team competence --- trauma system --- life-saving intervention --- trauma --- non-invasive external pelvic stabilizers --- bleeding --- pelvic fractures --- post mortem analysis --- biomechanical force --- pneumatic pelvic sling VBM® --- T-POD® --- cloth sling --- SAM Sling® --- trauma victims --- prehospital death --- Injury Severity Score (ISS) --- hemorrhage --- shock --- resuscitation --- coagulopathy --- oxygen transport --- endotheliopathy --- microcirculation --- macrocirculation --- orthopaedic trauma --- nutritional deficiencies --- vitamins --- lower extremity --- wound complications --- nutrition wound healing --- platelets --- immune system --- posttraumatic organ failure --- posttraumatic lung dysfunction --- posttraumatic hyperinflammation --- I-FABP --- biomarker --- intestinal damage --- hemorrhagic shock --- major trauma

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• Reference Manager
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Trauma is still a leading cause of death in patients below 40 years of age. Clinical management of severely injured patients is challenging in all phases of treatment during the clinical course. Numerous factors, such as injury severity, injury pattern, patient characteristics and trauma system, affect the decision-making process in our patients. After the successful initial management of an unstable multiply injured patient, secondary definitive surgeries and reconstructions may have a risk for further systemic complications and the deterioration of the patient’s physiology. A “Safe Definitive Surgery” (SDS) concept considers the dynamics of the clinical course (prehospital, operations, complications, etc.) and the patient’s physiology. Due to the repeated re-evaluation and assessment of the patient’s clinical course, dynamics and adaptation of the treatment strategy, the safe management of polytraumatized patients is possible. Many unanswered questions still exist and need to be addressed in future studies: Which patients profit by the damage control strategy and which do not? When is it best to start with the definitive fixation of fractures in multiply injured patients? How can one improve the quality of life in polytraumatized patients? What are the strategies in elderly severely injured patients? With this Special Issue, we would like to stimulate research in the field of polytrauma in order to shed light on the above-mentioned questions

pelvic ring fracture --- PCCD --- position --- associated injuries --- geriatric trauma --- scoring --- polytrauma --- ISS --- AIS --- geriatric patients --- orthogeriatric --- E-bike injuries --- outcome --- injury pattern comparison --- traumatic injury --- reactive oxygen species --- phagocytosis --- CD14 --- CD16 --- CD62L --- fMLP --- PMA --- emergency surgery --- trauma team competence --- trauma system --- life-saving intervention --- trauma --- non-invasive external pelvic stabilizers --- bleeding --- pelvic fractures --- post mortem analysis --- biomechanical force --- pneumatic pelvic sling VBM® --- T-POD® --- cloth sling --- SAM Sling® --- trauma victims --- prehospital death --- Injury Severity Score (ISS) --- hemorrhage --- shock --- resuscitation --- coagulopathy --- oxygen transport --- endotheliopathy --- microcirculation --- macrocirculation --- orthopaedic trauma --- nutritional deficiencies --- vitamins --- lower extremity --- wound complications --- nutrition wound healing --- platelets --- immune system --- posttraumatic organ failure --- posttraumatic lung dysfunction --- posttraumatic hyperinflammation --- I-FABP --- biomarker --- intestinal damage --- hemorrhagic shock --- major trauma