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Lichen Planus. --- Mouth Diseases.

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This book represents a guide to the academic, scientific and clinical applications of saliva as a diagnostic fluid. This volume is written by leaders in multiple fields and fulfills a demand for a broad understanding of saliva across a range of disciplines.

Medicine --- salivary biomarkers --- oral neoplasia --- periodontal disease/periodontitis --- smoking --- ethanol consumption --- real-time quantitative PCR --- enzyme-linked immune-sorbent assay --- immunohistochemistry --- bacteria --- HS-SPME-GC-MS --- MALDI-TOF MS --- silver nanoparticles --- VOCs --- obesity --- periodontitis --- cytokine --- inflammation --- saliva --- biomarkers --- oral cancer --- oral lichen planus --- psoriasis --- oral diseases --- oxidative stress --- antioxidants --- plaque psoriasis --- salivary glands --- cytokines --- nitrosative stress --- IgA --- alpha-amylase --- uric acid --- stress --- dental implants --- corrosion --- titanium --- metallic ions --- human papillomavirus --- oropharyngeal cancer --- meta-analysis --- salivary biomarkers --- oral neoplasia --- periodontal disease/periodontitis --- smoking --- ethanol consumption --- real-time quantitative PCR --- enzyme-linked immune-sorbent assay --- immunohistochemistry --- bacteria --- HS-SPME-GC-MS --- MALDI-TOF MS --- silver nanoparticles --- VOCs --- obesity --- periodontitis --- cytokine --- inflammation --- saliva --- biomarkers --- oral cancer --- oral lichen planus --- psoriasis --- oral diseases --- oxidative stress --- antioxidants --- plaque psoriasis --- salivary glands --- cytokines --- nitrosative stress --- IgA --- alpha-amylase --- uric acid --- stress --- dental implants --- corrosion --- titanium --- metallic ions --- human papillomavirus --- oropharyngeal cancer --- meta-analysis

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This Special Edition Issue on the “Pathogenesis and Treatment of Chronic Pruritus” contains an overview of various known causes of chronic pruritus and emerging therapeutics. Chronic pruritus is an itch that lasts longer than six weeks, and is associated with a variety of dermatologic, systemic, neurologic, and psychiatric etiologies. Itch negatively impacts patient quality of life, and has devastating psychosocial consequences. The manuscripts published in this Special Issue are also a showcase of the current understanding of the pathogenesis of chronic pruritus, along with its epidemiology, diagnostic workup, and therapeutic approaches used to treat chronic pruritus. A special focus is also placed on prurigo nodularis, a severely pruritic chronic inflammatory skin disease.

Medicine --- dupilumab --- IL-4 --- IL-13 --- pruritus --- chronic pruritus of unknown origin --- prurigo nodularis --- uremic pruritus --- lichen planus --- eosinophilic dermatosis of hematologic malignancy --- chronic pruritus --- mirtazapine --- chronic --- itch --- refractory --- treatment --- noradrenergic --- serotonergic --- antihistaminergic --- antidepressant --- skin --- atopic dermatitis --- ceramide --- pine tar --- drug-induced --- medication-related --- epidemiology --- inpatient --- disease burden --- national inpatient sample --- medical dermatology --- systematic review --- prurigo --- nodularis --- atopic --- dermatitis --- race --- gender --- comorbidities --- demographics --- pediatric --- children --- malignancy --- cancer --- neoplasm --- ion channels --- cell signaling --- Cav3.2 calcium channel --- RT-PCR --- wounds --- itch in wounds --- itch management --- aprepitant --- erlotinib --- EGFR --- epidermal growth factor receptor --- NK1R --- neurokinin1-receptor --- mycosis fungoides --- psoriasis --- associations --- lymphomatoid papulosis --- lymphoma --- racial differences --- nodular prurigo --- neuropathy --- therapeutic --- pathogenesis

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This Special Edition Issue on the “Pathogenesis and Treatment of Chronic Pruritus” contains an overview of various known causes of chronic pruritus and emerging therapeutics. Chronic pruritus is an itch that lasts longer than six weeks, and is associated with a variety of dermatologic, systemic, neurologic, and psychiatric etiologies. Itch negatively impacts patient quality of life, and has devastating psychosocial consequences. The manuscripts published in this Special Issue are also a showcase of the current understanding of the pathogenesis of chronic pruritus, along with its epidemiology, diagnostic workup, and therapeutic approaches used to treat chronic pruritus. A special focus is also placed on prurigo nodularis, a severely pruritic chronic inflammatory skin disease.

Medicine --- dupilumab --- IL-4 --- IL-13 --- pruritus --- chronic pruritus of unknown origin --- prurigo nodularis --- uremic pruritus --- lichen planus --- eosinophilic dermatosis of hematologic malignancy --- chronic pruritus --- mirtazapine --- chronic --- itch --- refractory --- treatment --- noradrenergic --- serotonergic --- antihistaminergic --- antidepressant --- skin --- atopic dermatitis --- ceramide --- pine tar --- drug-induced --- medication-related --- epidemiology --- inpatient --- disease burden --- national inpatient sample --- medical dermatology --- systematic review --- prurigo --- nodularis --- atopic --- dermatitis --- race --- gender --- comorbidities --- demographics --- pediatric --- children --- malignancy --- cancer --- neoplasm --- ion channels --- cell signaling --- Cav3.2 calcium channel --- RT-PCR --- wounds --- itch in wounds --- itch management --- aprepitant --- erlotinib --- EGFR --- epidermal growth factor receptor --- NK1R --- neurokinin1-receptor --- mycosis fungoides --- psoriasis --- associations --- lymphomatoid papulosis --- lymphoma --- racial differences --- nodular prurigo --- neuropathy --- therapeutic --- pathogenesis --- dupilumab --- IL-4 --- IL-13 --- pruritus --- chronic pruritus of unknown origin --- prurigo nodularis --- uremic pruritus --- lichen planus --- eosinophilic dermatosis of hematologic malignancy --- chronic pruritus --- mirtazapine --- chronic --- itch --- refractory --- treatment --- noradrenergic --- serotonergic --- antihistaminergic --- antidepressant --- skin --- atopic dermatitis --- ceramide --- pine tar --- drug-induced --- medication-related --- epidemiology --- inpatient --- disease burden --- national inpatient sample --- medical dermatology --- systematic review --- prurigo --- nodularis --- atopic --- dermatitis --- race --- gender --- comorbidities --- demographics --- pediatric --- children --- malignancy --- cancer --- neoplasm --- ion channels --- cell signaling --- Cav3.2 calcium channel --- RT-PCR --- wounds --- itch in wounds --- itch management --- aprepitant --- erlotinib --- EGFR --- epidermal growth factor receptor --- NK1R --- neurokinin1-receptor --- mycosis fungoides --- psoriasis --- associations --- lymphomatoid papulosis --- lymphoma --- racial differences --- nodular prurigo --- neuropathy --- therapeutic --- pathogenesis

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Mucoadhesive polymers are widely used in the design of dosage forms for transmucosal drug delivery to the eye, respiratory, gastrointestinal and reproductive tracts. These routes of drug administration offer a number of advantages including improved drug bioavailability, reduced frequency of administration, and the avoidance for the use of injections.

chitosan --- maltodextrin --- Caco-2 cells --- alkyl lactate --- mucosal drug delivery --- thermogelling polymers --- buccal mucosa drug delivery --- drug delivery --- triple co-culture model --- oral lichen planus --- mucoadhesive polymers --- cyclodextrins --- paediatric --- mucoadhesion --- nanoparticles --- pectin --- furosemide --- oral lyophilisates --- films --- wound healing --- pluronic f127 --- interpolymer complexes --- transmucosal permeations --- Alzheimer’s disease --- biocompatibility --- poly (vinylpyrrolidone) --- mucosal membranes --- scanning electron microscopic images --- pioglitazone --- hydrogel --- resuspendibility --- thermoresponsive polymers --- mucoadhesive microspheres --- trimethyl chitosan --- Candida albicans --- xanthan gum --- omeprazole --- texture profile analysis --- acrylated chitosan --- mucoadhesive --- clotrimazole --- clobetasol --- Carbopol® --- hydroxypropyl cellulose --- electrospinning --- chitosan derivatives --- in vitro permeability --- l-arginine --- resveratrol --- cytotoxicity --- retention --- thiolated hyaluronic acid --- Carbopol --- mucoadhesive polymer --- rheology --- Eudragit® E PO --- detachment force --- chitosan-catechol --- controlled release --- PLGA-PEG --- liposphere --- gellan gum --- storage and loss moduli --- thiolated chitosan --- interpolyelectrolyte complex --- poly(2-ethyl-2-oxazoline)