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Impurities originating from any part of the manufacturing or storage of drug products can potentially result in expensive product recalls and damage to a company's reputation - not to mention the serious threat posed to patient safety. Nowadays extractables and leachables assessment of all materials - and especially elastomeric and plastic components - forms an integral part of the submission for approval of a new drug system or medical device. With regulatory authorities such as the FDA and the MHRA demanding assurance that a product's integrity has been scrutinized - the pharmaceutical industry

Extracts. --- Leachate.

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Anaerobic bacteria --- Leachate --- Sanitary landfills --- Purification --- Leaching

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Leachate --- Sanitary landfills --- Congresses. --- Leaching --- Congresses --- Leachate - Congresses. --- Sanitary landfills - Leaching - Congresses.

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Sanitary landfills --- Leachate --- Water reuse --- Refuse and refuse disposal --- -Biodegradation

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Leachate --- Spoil banks --- Acid mine drainage --- Analysis. --- Testing.