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Tears --- Keratoconjunctivitis --- Keratoconjunctivitis Sicca --- Dacryocystorhinostomy --- secretion --- enzymology --- surgery --- methods

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Sjogren's syndrome. --- Gougerot-Sjogren's syndrome --- Sicca syndrome --- Keratoconjunctivitis sicca --- Rheumatoid arthritis --- Salivary glands --- Diseases

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This book presents in vivo captured high-magnification images of two conditions:  keratoconjunctivitis sicca (KCS, or dry eye), an extremely common disease of the ocular surface, and filamentary keratopathy, a relatively rare phenomenon most commonly associated with KCS. Although most of the images of KCS originated from patients with Sjögren’s syndrome, they fairly represent the broad spectrum of ocular surface changes seen in the condition. The appearance of the ocular surface and of the mucus component discernible in the tear film is clearly depicted, and long-term observations, less common KCS cases, and images showing iatrogenic epithelial damage are included. The images of filamentary keratopathy clearly reveal the components of the ocular surface appendices, termed filaments, and assist in explaining the mechanisms underlying the formation of these filaments. The photographs show phenomena captured in various illumination modes, without staining and after staining with diagnostic dyes, and the photographic sequences illustrate their dynamics. The images reflect the in vivo situation. Once aware of the various phenomena, anyone working with standard diagnostic equipment - the slit lamp and the diagnostic dyes- will be able to detect almost all of them. The book will be invaluable for all who deal with ocular surface diseases, including general practitioners, medical eye specialists, ocular surgeons, optometrists, opticians, and rheumatologists.

Eye -- Diseases -- Diagnosis. --- Eye -- Diseases. --- Ophthalmology. --- Dry Eye Syndromes --- Keratoconjunctivitis --- Eye Diseases --- Lacrimal Apparatus Diseases --- Conjunctivitis --- Diseases --- Conjunctival Diseases --- Keratoconjunctivitis Sicca --- Corneal Diseases --- Keratitis --- Medicine --- Health & Biological Sciences --- Ophthalmology & Optometry --- Keratoconjunctivitis sicca. --- Eye --- Diseases. --- Diseases and defects --- Medicine. --- Medicine & Public Health. --- Ophthalmology --- Dry eye syndromes

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Sjogren's Syndrome: Novel Insights in Pathogenic, Clinical and Therapeutic Aspects provides the reader with an overview of current knowledge about Sjogren's Syndrome. The book summarizes the huge amount of literature concerning related advances in genetic background, pathogenesis, clinical picture, and therapeutic approaches. It integrates basic immunology concepts, clinical aspects, and pharmacological issues. Scientific progress has allowed us to unmask novel pathogenic mechanisms, to perform genome wide studies, and to identify clinical and serological features associated with different disease subsets and, eventually, different disease prognoses. In addition, the increasing knowledge about SS pathogenesis provides the rationale to employ targeted therapies in SS as has already occurred in rheumatoid arthritis and systemic lupus erythematosus.

Sjogren's syndrome. --- Sjogren's Syndrome --- Sjogren Syndrome --- Sicca Syndrome --- Sjogrens Syndrome --- Syndrome, Sicca --- Syndrome, Sjogren's --- Gougerot-Sjogren's syndrome --- Sicca syndrome --- Keratoconjunctivitis sicca --- Rheumatoid arthritis --- Salivary glands --- Diseases

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The key knowledge assembled in this book comprises today’s most comprehensive resource on Sjögren’s syndrome.  Sjögren’s patients require the care of a wide variety of clinical and surgical specialists to treat their disease and improve their quality of life.  This volume presents a broad multi-disciplinary approach, enlisting the expertise of well-respected authors from around the world, covering the specialties of rheumatology, ophthalmology, oral medicine, oral surgery, otolaryngology, hematology, and others.   This practical clinical resource begins with an overview of Sjögren’s myths, pearls and tips, information for referring physicians, and diagnostic and classification and criteria.  The second section covers pathogenesis, providing the backbone for our understanding current diagnostics and therapeutics.  The third section is devoted to clinical manifestations and therapeutic considerations.  It covers the entire spectrum of symptoms and treatment, infused with the experience and astute clinical observations of the book’s contributors.  With system-wide coverage of local and systemic therapy, the book examines current therapy, biologics, and emerging therapeutic targets.   Presenting many international perspectives, this book creates an inter-connective conduit for the global community of Sjögren’s patients and physicians.

Sjogren's syndrome --- Gougerot-Sjogren's syndrome --- Sicca syndrome --- Diagnosis. --- Treatment. --- Medicine. --- Internal medicine. --- Rheumatology. --- Ophthalmology. --- Otorhinolaryngology. --- Medicine & Public Health. --- Internal Medicine. --- Keratoconjunctivitis sicca --- Rheumatoid arthritis --- Salivary glands --- Diseases --- Medicine, Internal --- Medicine --- Eye --- Ear, nose, and throat diseases --- ENT diseases --- Otorhinolaryngology --- Internal medicine --- Connective tissues --- Joints