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The most common chronic complication of diabetes mellitus (DM) is diabetic foot ulcers (DFUs), with a prevalence of four to ten percent among DM patients. Local circulation is an essential requirement for efficient wound healing, providing sufficient oxygen and nutrient delivery. Therefore it is possible that compression therapies can improve local circulation and improve clinical outcomes for patients with DFUs, as has been demonstrated for other wound types. Compression therapies apply controlled external pressure to promote local circulation by simulating vasodilation or reduction of venous congestion and edema. The controlled external pressure is applied using bandages, specialized stockings, or inflatable garments. Intermittent pneumatic compression (IPC) is a compression therapy utilizing sleeves that are inflated to a defined pressure before being deflated, simulating the effect of walking and weight-bearing on the venous system. A related treatment called compressed air massage utilizes a stream of compressed air directly on the affected area and may have similar local circulation effects. However, DFUs are a unique wound type and are often accompanied by contraindications for compression therapy including ischemia and peripheral vascular disease (PVD). The purpose of this report is to retrieve and review existing clinical efficacy evidence for compression therapy in the treatment of DFUs. Additionally this report aims to retrieve and review evidence for compression therapy cost-effectiveness, and to retrieve and review the existing compression therapy guidelines for the treatment of DFUs.

Bandages and bandaging. --- Foot --- Diabetics --- Ulcers. --- Care. --- Diabetes --- Wireless communication systems --- Patient monitoring --- Foot Ulcer --- Diabetic Foot --- Intermittent Pneumatic Compression Devices. --- Diabetes Complications --- Clinical medicine --- Clinical trial --- Diabetic foot ulcer --- Evidence-based medicine --- Health --- Health care --- Health sciences --- Medical guideline --- Medical specialties --- Medicine --- Ulcers --- Complications --- Safety measures. --- Equipment and supplies. --- therapy.