Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalog of the essential properties of families of molecules. Gene organization, amino acid sequences, physicochemical properties, and biological activity are presen

Chemokines --- Cytokines. --- Chemotactic cytokines --- Inflammatory peptides --- Intercrines --- Cellular immunity --- Immune response --- Cytokines --- Inflammation --- Peptides --- Regulation --- Mediators

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. Th

Cytokines --- Chemokines --- Chemotactic cytokines --- Inflammatory peptides --- Intercrines --- Inflammation --- Peptides --- Cellular immunity --- Immune response --- Mediators --- Regulation

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Chemokines. --- Immunology. --- Immunobiology --- Life sciences --- Serology --- Chemotactic cytokines --- Inflammatory peptides --- Intercrines --- Cytokines --- Inflammation --- Peptides --- Mediators

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

To date, there are over twenty different chemokine receptors, binding nearly fifty unique ligands that have been identified. In Chemokine Receptors, leading investigators attempt to distill the large body of literature ranging from basic molecular and cellular mechanism of chemokine receptors, to physiological and pathological roles of chemokines. Chemokines exhibit a tremendous functional diversity and participate in a wide variety of processes that include inflammation, innate and adaptive immunity, immune cell differentiation, angiogenesis, tumorigenesis, development, neurobiology and viral pathogenesis. Chemokine Receptors targets the pharmaceutical industry, provides an authoritative perspective on the future direction of this field, and insights into areas of active development of novel therapeutics.

Chemokines. --- Cell receptors. --- Cell membrane receptors --- Cell surface receptors --- Receptors, Cell --- Binding sites (Biochemistry) --- Cell membranes --- Proteins --- Chemotactic cytokines --- Inflammatory peptides --- Intercrines --- Cytokines --- Inflammation --- Peptides --- Mediators

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This edition of Current Topics in Microbiology and Immunology examines the role of chemokines and chemokine receptors in host defense and disease development following viral infection. Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue. There are now four sub-families of chemokines identified based on defined structural criteria relating to the positional location of conserved cysteine residues within the amino-terminus of the protein. Chemokines are now recognized as important in numerous biological processes ranging from maintaining the organizational integrity of secondary lymphoid tissue to participating in various aspects of both innate and adaptive immune responses following microbial infection. With this in mind, this book highlights the functional roles of chemokines and their receptors in participating in various aspects of the immune response against well-known viral pathogens.

Chemokines --- Virus diseases --- Pathophysiology. --- Pathogenesis. --- Chemotactic cytokines --- Inflammatory peptides --- Intercrines --- Cytokines --- Inflammation --- Peptides --- Viral diseases --- Viral infections --- Virus infections --- Communicable diseases --- Medical virology --- Pathogenic viruses --- Mediators --- Microbiology. --- Medical Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Medical microbiology.