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Inflammatory bowel disease (IBD) affects 1% of people worldwide. This condition is partly inherited, and genetic research has made enormous progress during the last few years, providing important insight into disease pathogenesis. This book provides a concise but complete overview of existing knowledge, with particular focus on the molecular and genetic mechanisms at the basis of IBD. Invited experts, at the frontline of IBD research, introduce basic concepts in the pathophysiology of IBD and its two major forms Crohn’s disease and ulcerative colitis, provide a historical perspective and highlight latest discoveries of IBD genetic research, describe how this information has helped to unravel novel pathogenetic pathways, and formulate a vision for future investigations and their clinical application in IBD. State-of-the-art information contained in this book is an exceptional resource for all those in the biomedical field with a specific interest in IBD, including basic scientists, gastroenterologists, GI specialist doctors and research nurses, but also medical and biomedical students.

Human genetics. --- Inflammatory bowel diseases -- Diagnosis. --- Inflammatory bowel diseases -- Popular works.. --- Medicine. --- Inflammatory bowel diseases --- Gastroenteritis --- Biology --- Gastrointestinal Diseases --- Biological Science Disciplines --- Digestive System Diseases --- Natural Science Disciplines --- Diseases --- Disciplines and Occupations --- Genetics --- Inflammatory Bowel Diseases --- Medicine --- Health & Biological Sciences --- Pathology --- Genetic aspects --- Molecular aspects --- Molecular genetics. --- Inflammatory bowel diseases. --- IBD (Disease) --- Inflammatory bowel disease --- Intestines --- Inflammation --- Molecular biology. --- Biomedicine. --- Human Genetics. --- Molecular Medicine. --- Biomedicine general. --- Molecular biology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Physicians --- Heredity, Human --- Physical anthropology --- Health Workforce --- Biomedicine, general. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology