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Using the published work of Nobel Laureate Niels Kaj Jerne, this book shows how he developd his ideas. The book is a compilation of his published work, but in fact it is much more than that. Whether the reader wants to read the book systematically, or only browse, it opens a fascinating world of hypotheses, theories, facts and vistas. His selection theory, his view of how immunological diversity is created, and his concept of lymphocytes interacting as a network, reveals Jerne's revolutionary spirit. The book ought to be a rich source of inspiration for everyone interested in science and how s
Immune system. --- Immunological system --- Anatomy --- Immunology
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Immune system --- Immunological system --- Anatomy --- Immunology --- Physiology.
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In Immune, Philipp Dettmer takes readers on a journey through the fortress of the human body and its defences. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body. Challenging what you know and think about your own body and how it defends you against all sorts of maladies and how it might also eventually be your own downfall, Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.
Immune system --- Immunological system --- Anatomy --- Immunology
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Preface. Part I: An Overview of Immunology. Introduction to the Immune System. Part II: Case Studies in Immune Complexity: Experiments. Cytokines: A Common Signaling System for Cell Growth, Inflammation, Immunity, and Differentiation. Th1/Th2 Effector Choice in the Immune System: A Developmental Program Influenced by Cytokine Signals. Oral Tolerance. Part III: Design Principles for the Immune System. An Introduction to Immuno-Ecology and Immuno-Informatics. The Creation of Immune Specificity. Diversity in the Immune System. T Cells Obey the Tenets of Signal Detection Theory. Diffuse Feedback f
Immune system --- System theory --- Biological systems --- Immunological system --- Anatomy --- Immunology
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This book presents the evidence for the belief that psoriasis is a disease of abnormal keratinocyte proliferation induced by T cells. The latest approaches to investigating the immunopathogenesis of this disease, and a review of previous findings, are presented to give an overall picture of the current knowledge in this field. Each topic is discussed in detail, clearly illustrated and well referenced. The book should prove invaluable to clinical dermatologists, and researchers in the fields of immunology and dermatology who have an interest in skin diseases.
Psoriasis. --- Immune system. --- Immunological system --- Anatomy --- Immunology --- Skin --- Diseases
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The understanding of chemokines, the proteins that control the migration of cells, and their receptors, is critical to the study of causes and therapies for a wide range of human diseases and infections, including certain types of cancer, inflammatory diseases, HIV, and malaria. This volume, focusing on chemokine structure and function, as well as signaling, and its companion volume (Methods in Enzymology volume 461, focusing on chemokines as potential targets for disease intervention) provide a comprehensive overview and time-tested protocols in this field, making it an essential refer
Chemokines. --- Immune system. --- Immunological system --- Chemotactic cytokines --- Inflammatory peptides --- Intercrines --- Anatomy --- Immunology --- Cytokines --- Inflammation --- Peptides --- Mediators
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Immune System --- Immunity --- Immunotherapy. --- Immune system --- Système immunitaire --- Immunité --- physiology. --- physiopathology. --- Immunology --- Immunological system --- Anatomy
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Immunosenescence is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. It represents a rapidly progressing science in the aging field, with a vertiginous volume of new data, knowledge and concepts concerning these changes. We are poised to be in a position to translate these accumulated data into the clinical setting via better understanding of the contribution of immunosenescence to age-associated pathologies, and their prevention by appropriate interventions. This authoritative handbook seeks to encompass the current state of our knowledge on the multitude of those changes to immunity related to aging, with contributions from experts in the research and clinical areas. This book therefore considers methods and models for studying immunosenescence; cellular immunosenescence of T cells, B cells, neutrophils, antigen presenting cells, NK, NKT and stem cells; genetics; mechanisms including receptors and signal transduction; mitochondria; proteasome; cytokines; neuro-endocrine-immune networks; inflammation; thymus; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; modulation by nutrition, lipids, vaccination and the question “can interventions to influence immunosenescence be realistically proposed based on our current state of knowledge?”.
Medicine. --- Biomedicine general. --- Health Workforce --- Immune system --- Aging. --- Immunological system --- Anatomy --- Immunology --- Biomedicine, general.
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Pathbreaking research offers new hope for treating brain diseases and injuries and for maintaining brain health even into old age In the past, the brain was considered an autonomous organ, self-contained and completely separate from the body's immune system. But over the past twenty years, neuroimmunologist Michal Schwartz, together with her research team, not only has overturned this misconception but has brought to light revolutionary new understandings of brain health and repair. In this book Schwartz describes her research journey, her experiments, and the triumphs and setbacks that led to the discovery of connections between immune system and brain. Michal Schwartz, with Anat London, also explains the significance of the findings for future treatments of brain disorders and injuries, spinal cord injuries, glaucoma, depression, and other conditions such as brain aging and Alzheimer's and Parkinson's diseases. Scientists, physicians, medical students, and all readers with an interest in brain function and its relationship to the immune system in health and disease will find this book a valuable resource. With general readers in mind, the authors provide a useful primer to explain scientific terms and concepts discussed in the book.
Immune system. --- Brain --- Immunological system --- Anatomy --- Immunology --- Aging. --- Neuroimmunology. --- Nervous system --- Neuroimmunology --- Neuroimmunomodulation --- Neurosciences --- Diseases --- Immunological aspects.
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"The Paradox of the Immune System: Protection, Inflammation, Autoimmune Disease and Beyond provides a provocative approach to immunology as a "double-edged sword." While it is our greatest protector, it is also the cause of chronic inflammation that leads to autoimmune disease, cancer and infectious diseases like COVID-19. Sections cover the basic science of immunology and its intimate genetic associations, biomedical hypotheses asserting immunology as the basis of all human diseases, and elaborate on immunology as "the enemy within us." This engaging, original approach to a science so personal provides new and invaluable understanding on the bioscience that controls our lives."--
Immune system. --- Immunology. --- Immunobiology --- Life sciences --- Serology --- Immunological system --- Anatomy --- Immunology --- Immune System --- Inflammation --- Autoimmunity --- Allergy and Immunology --- immunology
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