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Immunologic memory. --- B-Lymphocytes --- Immunologic Memory --- Physiology --- Physiology. --- Immunologic memory

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Aging --- CD4-Positive T-Lymphocytes --- Immunologic Memory --- Cytokines --- Th1 Cells --- immunology --- physiology --- immunology

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Immunological memory has fascinated microbiologists and immunologists for decades as one of the new frontiers to conquer to better understand the response to pathogens, cancer and vaccination. Over the past decade, attention has turned to the intrinsic properties of the memory T cells themselves, as it has become clear that the eradication of both infected cells and tumors requires T cells. This book is an attempt to capture the wave of discoveries associated with these recent studies. Its chapters represent a wide collection of topics related to memory T cells by laboratories that have invested their skills and knowledge to understand the biology and the principles upon which memory T cells are generated, maintained and expanded upon re-encounter with antigen. Ultimately, these studies are all aimed at a better understanding of the function of memory T cells in protection against disease.

Immunologic memory. --- T cells. --- Immunologic memory --- T cells --- Lymphocytes --- Adaptive Immunity --- Immunity --- Leukocytes, Mononuclear --- Immune System Phenomena --- Leukocytes --- Phenomena and Processes --- Blood Cells --- Immune System --- Blood --- Cells --- Hemic and Immune Systems --- T-Lymphocytes --- Autoimmunity --- Immunologic Memory --- Immunity, Cellular --- Anatomy --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Biophysics --- T lymphocytes --- Thymus-dependent cells --- Thymus-dependent lymphocytes --- Thymus-derived cells --- Immune memory --- Immunological memory --- Memory, Immune --- Memory, Immunologic --- Medicine. --- Human physiology. --- Molecular biology. --- Neurochemistry. --- Neurology. --- Biomedicine. --- Human Physiology. --- Molecular Medicine. --- Medicine --- Nervous system --- Neuropsychiatry --- Biochemistry --- Neurosciences --- Molecular biochemistry --- Molecular biophysics --- Biomolecules --- Systems biology --- Human biology --- Medical sciences --- Physiology --- Human body --- Clinical sciences --- Medical profession --- Life sciences --- Pathology --- Physicians --- Diseases --- Health Workforce --- Neurology .

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In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture “Immunological Recognition of Self” emphasizing the central argument of immunological tolerance in “How does the vertebrate organism recognize self from nonself in this the immunological sense—and how did the capacity evolve.” The concept of self is linked to the concept of biological self identity. All organisms, from bacteria to higher animals, possess recognition systems to defend themselves from nonself. Even in the context of the limited number of metazoan phyla that have been studied in detail, we can now describe many of the alternative mechanism of immune recognition that have emerged at varying points in phylogeny. Two different arms—the innate and adaptive immune system—have emerged at different moments in evolution, and they are conceptually different. The ultimate goals of immune biology include reconstructing the molecular networks underlying immune processes.

Cellular recognition. --- Immunologic memory. --- Natural immunity. --- Immunity --- Immune Tolerance --- Immunomodulation --- Immune System Phenomena --- Phenomena and Processes --- Immune System Processes --- Immunity, Innate --- Adaptive Immunity --- Self Tolerance --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Immunity. --- Medicine. --- Immunology. --- Biomedicine. --- Biomedicine general. --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Immunology --- Biomedicine, general. --- Health Workforce