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Glycomics. --- Glycobiology --- Genomics --- Molecular biology --- Carbohydrates --- Glicòmica --- Immunitat

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Histocompatibility. --- Immune response. --- Major Histocompatibility Complex. --- Virus Diseases --- Immunität (Medizin). --- MHC. --- immunology. --- MAJOR HISTOCOMPATIBILITY COMPLEX --- VIRUS DISEASES --- IMMUNOLOGY

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Goethe, Johann Wolfgang von, --- Schiller, Friedrich von, --- Schiller, Friedrich, --- Criticism and interpretation. --- Deutsch. --- Literatur. --- Klassik. --- Immunität. --- Medizin, Motiv. --- Goethe, Johann Wolfgang von --- Schiller, Friedrich von

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The topic of this book, Collectins, is a family of proteins whose major function is in innate immunity, where Collectins act as pattern recognition receptors (PRRs). In general they recognize targets such as microbial surfaces and apoptotic cells, and once bound to a target, Collectins promote the clearance of microorganisms and damaged host tissue. New cell-surface proteins and glycoproteins, which act as Collectin receptors, are currently being identified. Some Collectins, particularly MBL, activate the complement system, which enhances the ability of antibodies to fight pathogens, via three MBL-associated proteases, the MASPs. Additionally, recent research has begun to show wider-ranging activities of Collectins, such as: · Their role in metabolism, and therefore their involvement in lifestyle diseases such as obesity and cardiovascular disease. · Their ability to modulate the adaptive immune response, as well as to recognize and trigger apoptosis of cancer cells, which makes them effective in the annihilation of cancer cells with multiple mutations. · The regulation of their expression by gonadal steroid hormones implicates them with critical roles in both male and female fertility. · Altered levels of Collectins have been associated with various autoimmune diseases. This book brings together current knowledge of the structure, functions and biological activities of Collectins, to describe their integral role in human health.

Immunology. --- Medical microbiology. --- Proteins . --- Medical Microbiology. --- Protein Science. --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Immunobiology --- Life sciences --- Serology --- Natural immunity. --- Disease resistance --- Host resistance --- Innate immunity --- Innate resistance --- Native immunity --- Natural resistance --- Nonspecific immunity --- Resistance to disease --- Immunity --- Lectines --- Immunitat --- Antígens --- Autoimmunitat --- Hemòlisi --- Immunitat cel·lular --- Immunodeficiència --- Immunoquímica --- Resposta immunitària --- Vacunació --- Vacunes --- Lectina --- Lectins --- Immunoglobulines

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This volume explores the rapidly evolving field of HLA typing and its use in both the laboratory setting and in silico methods. The chapters in this book discuss high-throughput methods for HLA typing; wet lab protocols; microarray data and its uses; in silico tools for the identification of HLA alleles from DNA and RNA next-generation-sequencing data, as well as HLA haplotype frequency estimation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, HLA Typing: Methods and Protocols is a valuable resource for any researcher interested in learning more about this developing field.

Immunology. --- Immunobiology --- Life sciences --- Serology --- Antígens HLA --- Immunologia --- Biologia --- Complements (Immunitat) --- Immunofarmacologia --- Immunologia clínica --- Immunologia de la trasplantació --- Neuroimmunologia --- Resposta immunitària --- Sistema immunitari --- Antígens d'histocompatibilitat HLA --- Antígens de trasplantament HLA --- Antígens dels leucòcits humans --- HLA --- Sistema HLA --- Antígens --- Histocompatibilitat