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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Psychiatry --- Psychiatric Disease --- Metabolic Disorders --- Immune Disorders --- Etiology --- treatment

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Psychiatry --- Psychiatric Disease --- Metabolic Disorders --- Immune Disorders --- Etiology --- treatment --- Psychiatric Disease --- Metabolic Disorders --- Immune Disorders --- Etiology --- treatment

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Pathological haematology --- Immunologic diseases. --- Immune diseases --- Immune disorders --- Immune system --- Immunologic disorders --- Immunological diseases --- Diseases

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In the seventeenth century, smallpox reigned as the world's worst killer. Luck, more than anything else, decided who would live and who would die. That is, until Lady Mary Wortley Montagu, an English aristocrat, moved to Constantinople and noticed the Turkish practice of ""ingrafting"" or inoculation, which, she wrote, made ""the small- pox...entirely harmless."" Convinced by what she witnessed, she allowed her six-year-old son to be ingrafted, and the treatment was a complete success--the young Montagu enjoyed lifelong immunity from smallpox.

Immunologic diseases --- Medicine. --- Health Workforce --- Immune diseases --- Immune disorders --- Immune system --- Immunologic disorders --- Immunological diseases --- Diseases --- Medicine

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This book is a compilation of chapters, of which two chapters review the treatment strategies for fibromyalgia syndrome (FMS), and one chapter describes the role of mitochondrial dysfunction and related pathology in the FMS pathogenesis and reviews the appropriate treatment moieties. This book chapter reviews the phenotypic changes that alter the diagnostic criteria and disease activity measures when FMS is comorbid in three potentially painful selected rheumatic diseases. The introductory preface takes the form of an editorial in which I challenge the concept that inflammation, measured as cytokine activity, plays a prominent role in the FMS pathogenesis. All of these chapters and the Preface are authoritative and accomplished discussions that provide novel perspectives on rarely addressed FMS topics.

Immunologic diseases. --- Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Immune diseases --- Immune disorders --- Immune system --- Immunologic disorders --- Immunological diseases --- Diseases --- Medicine --- Immunology --- Allergology and Rheumatology --- Health Sciences