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Orthomyxoviridae --- Orthomyxoviridae infections --- Immunity, innate --- Interferons --- Sus scrofa --- Influenzavirus A --- genetics --- veterinary
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Grippe aviaire --- Influenzavirus A H5N1 --- Virus --- Politique sanitaire --- Politique pharmaceutique --- Lobbying --- Prévention --- Épidémiologie --- Coopération internationale
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Influenza vaccines. --- Influenza viruses. --- Influenza. --- Influenza --- Influenza vaccines --- Influenza viruses --- Orthomyxoviruses --- Influenza virus vaccines --- Viral vaccines --- Flu --- Flu, Respiratory --- Grippe --- Respiratory flu --- Respiratory infections --- Virus diseases --- INFLUENZAVIRUS A --- RNA VIRUSES --- INFLUENZA, HUMAN --- INFLUENZA VACCINES --- METABOLISM --- IMMUNOLOGY --- PATHOGENICITY --- HISTORY
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Recent years have seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans resulting in numerous fatalities. The rapid expansion in their geographic distribution and the possibility that these viruses could acquire the ability to spread from person to person raise the risk that such a virus could cause a global pandemic with high morbidity and mortality. An effective influenza vaccine represents the best approach to prevent and control such an emerging pandemic. However, current influenza vaccines are directed at existing seasonal influenza viruses, which have limited antigenic relationships to the highly pathogenic H5N1 strains. Concerns about pandemic preparedness have greatly stimulated research activities to develop effective vaccines for pandemic influenza viruses, and to overcome the limitations inherent in current approaches to vaccine production and distribution. These limitations include the use of embryonated chicken eggs as the substrate for vaccine production; which is time-consuming and could involve potential biohazards in growth of new virus strains. Other limitations include the requirement that the current inactivated influenza vaccines be administered using needles and syringes, requiring trained personnel, which could be a bottleneck when attempting to vaccinate large populations in mass campaigns. In addition, the current inactivated vaccines which are delivered by injection elicit limited protective immunity in the upper respiratory tract where the infection process is initiated. Most of these limitations of the current vaccines are being addressed by research on novel approaches to vaccine development and delivery that are described in many of the chapters in this volume.
Disease Outbreaks. --- Influenza vaccines. --- Influenza Vaccines -- therapeutic use. --- Influenza, Human. --- Influenzavirus A. --- Influenza Vaccines --- Influenzavirus A --- Influenza, Human --- Disease Outbreaks --- Orthomyxoviridae --- Viral Vaccines --- Public Health --- Orthomyxoviridae Infections --- Respiratory Tract Infections --- Environment and Public Health --- RNA Viruses --- Vaccines --- Respiratory Tract Diseases --- RNA Virus Infections --- Diseases --- Biological Products --- Virus Diseases --- Viruses --- Health Care --- Vertebrate Viruses --- Complex Mixtures --- Organisms --- Chemicals and Drugs --- Microbiology & Immunology --- Biology --- Health & Biological Sciences --- Viral vaccines. --- Virus vaccines --- Influenza virus vaccines --- Medicine. --- Immunology. --- Pharmacology. --- Virology. --- Public health. --- Biomedicine. --- Pharmacology/Toxicology. --- Public Health. --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Sanitary affairs --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Microbiology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Pathology --- Physicians --- Physiological effect --- Viral vaccines --- Medical virology. --- Toxicology. --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Medical microbiology --- Virology --- Virus diseases --- Toxicology
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The emergence of H5N1 avian influenza in 1997 and of the influenza A H1N1 of swine origin in 2009 calls for new, rapid and sustainable solutions for both seasonal and pandemic influenza viruses. During the last ten years, science and technology have made enormous progress, and we are now able to monitor in real time the genetics of viruses while they spread globally, to make more powerful vaccines using novel adjuvants, and to generate viruses in the laboratory using reverse genetics. This volume not only provides state-of-the-art information on the biology of influenza viruses and on influenza vaccines, but is also designed to be a resource to face the present H1N1 pandemic and to plan for long-term global and sustainable solutions.
Influenza A virus -- Immunology. --- Influenza B virus -- Immunology. --- Influenza Vaccines -- Therapeutic use. --- Influenza vaccines. --- Influenza viruses. --- Influenza, Human. --- Influenza vaccines --- Influenza --- Influenza viruses --- Orthomyxoviridae Infections --- Influenza A virus --- Respiratory Tract Infections --- Viral Vaccines --- Respiratory Tract Diseases --- Vaccines --- RNA Virus Infections --- Influenzavirus A --- Influenza A Virus, H1N1 Subtype --- Influenza Vaccines --- Influenza, Human --- Orthomyxoviridae --- Virus Diseases --- Diseases --- Biological Products --- RNA Viruses --- Complex Mixtures --- Chemicals and Drugs --- Vertebrate Viruses --- Viruses --- Organisms --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Influenza. --- Flu --- Flu, Respiratory --- Grippe --- Respiratory flu --- Influenza virus vaccines --- Medicine. --- Virology. --- Life sciences. --- Biomedicine. --- Life Sciences, general. --- Orthomyxoviruses --- Respiratory infections --- Virus diseases --- Viral vaccines --- Medical virology. --- Biosciences --- Sciences, Life --- Science --- Medical microbiology --- Virology --- Microbiology
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"The 2009 H1N1 vaccination campaign was one of the largest public health campaigns in U.S. history, vaccinating one-quarter of the population in the first three months. The Institute of Medicine held three workshops in Raleigh, NC; Austin, TX; and Seattle, WA to learn from participants' experiences during the campaign and improve future emergency vaccination programs."
H1N1 influenza --- Influenza vaccines --- Vaccination --- Influenza A virus --- Viral Vaccines --- Immunization Programs --- North America --- Orthomyxoviridae Infections --- Respiratory Tract Infections --- Vaccines --- Immunization --- Immunotherapy, Active --- Respiratory Tract Diseases --- Preventive Health Services --- RNA Virus Infections --- Americas --- Influenzavirus A --- Virus Diseases --- Biological Products --- Health Services --- Orthomyxoviridae --- Primary Prevention --- Diseases --- Geographic Locations --- Community Health Services --- Communicable Disease Control --- Influenza A Virus, H1N1 Subtype --- Mass Vaccination --- United States --- Influenza Vaccines --- Influenza, Human --- Geographicals --- Immunotherapy --- Complex Mixtures --- RNA Viruses --- Public Health Practice --- Health Care Facilities, Manpower, and Services --- Immunologic Techniques --- Public Health --- Vertebrate Viruses --- Health Care --- Immunomodulation --- Chemicals and Drugs --- Investigative Techniques --- Viruses --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biological Therapy --- Environment and Public Health --- Organisms --- Therapeutics --- Health & Biological Sciences --- Communicable Diseases --- Prevention --- Vaccination. --- H1N1 flu --- Novel H1N1 flu --- Novel H1N1 influenza --- Novel influenza A --- Swine flu (H1N1) --- Swine influenza (H1N1) --- Swine influenza
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"In March and early April 2009, a new, swine-origin 2009-H1N1 influenza A virus emerged in Mexico and the United States. During the first few weeks of surveillance, the virus spread by human-to-human transmission worldwide to over 30 countries. On June 11, 2009, the World Health Organization (WHO) raised the worldwide pandemic alert level to Phase 6 in response to the ongoing global spread of the novel influenza A (H1N1) virus. By October 30, 2009, the H1N1 influenza A had spread to 191 countries and resulted in 5,700 fatalities. A national emergency was declared in the United States and the swine flu joined SARS and the avian flu as pandemics of the 21st century. Vaccination is currently available, but in limited supply, and with a 60 percent effectiveness rate against the virus. The story of how this new influenza virus spread out of Mexico to other parts of North America and then on to Europe, the Far East, and now Australia and the Pacific Rim countries has its origins in the global interconnectedness of travel, trade, and tourism. Given the rapid spread of the virus, the international scientific, public health, security, and policy communities had to mobilize quickly to characterize this unique virus and address its potential effects. The World Health Organization and Centers for Disease Control have played critical roles in the surveillance, detection and responses to the H1N1 virus. The Domestic and International Impacts of the 2009-H1N1 Influenza A Pandemic: Global Challenges, Global Solutions aimed to examine the evolutionary origins of the H1N1 virus and evaluate its potential public health and socioeconomic consequences, while monitoring and mitigating the impact of a fast-moving pandemic. The rapporteurs for this workshop reported on the need for increased and geographically robust global influenza vaccine production capacities; enhanced and sustained interpandemic demand for seasonal influenza vaccines; clear "triggers" for pandemic alert levels; and accelerated research collaboration on new vaccine manufacturing techniques. This book will be an essential guide for healthcare professionals, policymakers, drug manufacturers and investigators."--executive summary.
H1N1 influenza --- Influenza --- Epidemics --- Communicable diseases --- Animals as carriers of disease --- World health --- Public Health --- Health --- Publication Formats --- Influenza A virus --- Respiratory Tract Infections --- Orthomyxoviridae Infections --- Disease Transmission, Infectious --- Influenzavirus A --- Population Characteristics --- Respiratory Tract Diseases --- Medicine --- RNA Virus Infections --- Environment and Public Health --- Publication Characteristics --- Virus Diseases --- Health Care --- Diseases --- Orthomyxoviridae --- Health Occupations --- RNA Viruses --- Disciplines and Occupations --- Vertebrate Viruses --- Viruses --- Organisms --- Influenza A Virus, H1N1 Subtype --- Epidemiology --- Congresses --- Disease Outbreaks --- World Health --- Disease Vectors --- Influenza, Human --- Health & Biological Sciences --- Communicable Diseases --- Prevention --- Transmission --- H1N1 influenza. --- Epidemics. --- Animals as carriers of disease. --- World health. --- Prevention. --- Epidemiology. --- Transmission. --- Disease outbreaks --- Outbreaks of disease --- Pestilences --- Flu --- Flu, Respiratory --- Grippe --- Respiratory flu --- H1N1 flu --- Novel H1N1 flu --- Novel H1N1 influenza --- Novel influenza A --- Swine flu (H1N1) --- Swine influenza (H1N1) --- Global health --- International health --- Carriers of disease --- Disease vectors --- Vectors of disease --- Communicable disease transmission --- Disease transmission --- Germs, Spread of --- Spread of communicable diseases --- Spread of germs --- Transmission of diseases --- Outbreaks --- Respiratory infections --- Virus diseases --- Swine influenza --- Public health --- Medical geography --- Zoology, Medical --- Zoonoses --- International cooperation --- Pandemics
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This book contains comprehensive and updated information on how to perform Avian Influenza and Newcastle Disease diagnosis from the suspicion in the field to the characterisation of isolates. It provides guidelines to outbreak management, field investigation, necropsy techniques, sampling methods and complete laboratory diagnosis, including molecular methods. The outstanding images collected from field outbreaks, including clinical and pathological findings, and the selection of laboratory protocols make this publication unique. It will therefore be an invaluable tool for all veterinarians, scientists, animal health professionals, and public health officials involved in the management of these infections. .
Avian influenza. --- Avian influenza --- Newcastle disease --- Poultry --- Influenza in Birds --- Influenza A virus --- Newcastle Disease --- Disease Outbreaks --- Influenzavirus A --- Bird Diseases --- Meat --- Avulavirus Infections --- Animals, Domestic --- Orthomyxoviridae Infections --- Public Health --- Poultry Diseases --- Birds --- Animal Diseases --- RNA Virus Infections --- Orthomyxoviridae --- Vertebrates --- Animal Population Groups --- Food --- Environment and Public Health --- Paramyxoviridae Infections --- Animals --- RNA Viruses --- Health Care --- Mononegavirales Infections --- Chordata --- Virus Diseases --- Diseases --- Food and Beverages --- Eukaryota --- Vertebrate Viruses --- Technology, Industry, Agriculture --- Viruses --- Organisms --- Medicine - General --- Veterinary Medicine --- Health & Biological Sciences --- Medicine --- Diagnosis --- Epidemiology --- Virus diseases --- Diagnosis. --- Epidemiology. --- Virus diseases. --- Virus diseases in poultry --- Avian pneumoencephalitis --- Fowl pest --- Avian flu --- Bird flu --- Fowl plague --- Influenza in birds --- Medicine. --- Laboratory medicine. --- Virology. --- Health promotion. --- Infectious diseases. --- Veterinary medicine. --- Biomedicine. --- Laboratory Medicine. --- Veterinary Medicine. --- Health Promotion and Disease Prevention. --- Infectious Diseases. --- Influenza --- Medical laboratories. --- Emerging infectious diseases. --- Medical virology. --- Veterinary Medicine/Veterinary Science. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Animal health --- Domestic animals --- Livestock --- Medical microbiology --- Virology --- Diagnosis, Laboratory --- Health facilities --- Laboratories --- Losses --- Health Workforce --- Microbiology --- Health promotion programs --- Health promotion services --- Promotion of health --- Wellness programs --- Preventive health services --- Health education --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis
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Influenza A virus --- Swine influenza --- Influenza A virus. --- Genetic aspects --- United States. --- Orthomyxovirus type A --- Influenza viruses --- Influenza in swine --- SIV flu (Swine influenzavirus flu) --- Swine flu --- Swine influenzavirus flu --- Influenza --- Swine --- Virus diseases --- ABŞ --- ABSh --- Ameerika Ühendriigid --- America (Republic) --- Amerika Birlăshmish Shtatlary --- Amerika Birlăşmi Ştatları --- Amerika Birlăşmiş Ştatları --- Amerika ka Kelenyalen Jamanaw --- Amerika Qūrama Shtattary --- Amerika Qŭshma Shtatlari --- Amerika Qushma Shtattary --- Amerika (Republic) --- Amerikai Egyesült Államok --- Amerikanʹ Veĭtʹsėndi͡avks Shtattnė --- Amerikări Pĕrleshu̇llĕ Shtatsem --- Amerikas Forenede Stater --- Amerikayi Miatsʻyal Nahangner --- Ameriketako Estatu Batuak --- Amirika Carékat --- AQSh --- Ar. ha-B. --- Arhab --- Artsot ha-Berit --- Artzois Ha'bris --- Bí-kok --- Ē.P.A. --- É.-U. --- EE.UU. --- Egyesült Államok --- ĒPA --- Estados Unidos --- Estados Unidos da América do Norte --- Estados Unidos de América --- Estaos Xuníos --- Estaos Xuníos d'América --- Estatos Unitos --- Estatos Unitos d'America --- Estats Units d'Amèrica --- Ètats-Unis d'Amèrica --- États-Unis d'Amérique --- ÉU --- Fareyniḳṭe Shṭaṭn --- Feriene Steaten --- Feriene Steaten fan Amearika --- Forente stater --- FS --- Hēnomenai Politeiai Amerikēs --- Hēnōmenes Politeies tēs Amerikēs --- Hiwsisayin Amerikayi Miatsʻeal Tērutʻiwnkʻ --- Istadus Unidus --- Jungtinės Amerikos valstybės --- Mei guo --- Mei-kuo --- Meiguo --- Mî-koet --- Miatsʻyal Nahangner --- Miguk --- Na Stàitean Aonaichte --- NSA --- S.U.A. --- SAD --- Saharat ʻAmērikā --- SASht --- Severo-Amerikanskie Shtaty --- Severo-Amerikanskie Soedinennye Shtaty --- Si͡evero-Amerikanskīe Soedinennye Shtaty --- Sjedinjene Američke Države --- Soedinennye Shtaty Ameriki --- Soedinennye Shtaty Severnoĭ Ameriki --- Soedinennye Shtaty Si͡evernoĭ Ameriki --- Spojené obce severoamerické --- Spojené staty americké --- SShA --- Stadoù-Unanet Amerika --- Stáit Aontaithe Mheiriceá --- Stany Zjednoczone --- Stati Uniti --- Stati Uniti d'America --- Stâts Unîts --- Stâts Unîts di Americhe --- Steatyn Unnaneysit --- Steatyn Unnaneysit America --- SUA --- Sŭedineni amerikanski shtati --- Sŭedinenite shtati --- Tetã peteĩ reko Amérikagua --- U.S. --- U.S.A. --- United States of America --- Unol Daleithiau --- Unol Daleithiau America --- Unuiĝintaj Ŝtatoj de Ameriko --- US --- USA --- Usono --- Vaeinigte Staatn --- Vaeinigte Staatn vo Amerika --- Vereinigte Staaten --- Vereinigte Staaten von Amerika --- Verenigde State van Amerika --- Verenigde Staten --- VS --- VSA --- Wááshindoon Bikéyah Ałhidadiidzooígíí --- Wilāyāt al-Muttaḥidah --- Wilāyāt al-Muttaḥidah al-Amirīkīyah --- Wilāyāt al-Muttaḥidah al-Amrīkīyah --- Yhdysvallat --- Yunaeted Stet --- Yunaeted Stet blong Amerika --- ZDA --- Združene države Amerike --- Zʹi͡ednani Derz͡havy Ameryky --- Zjadnośone staty Ameriki --- Zluchanyi͡a Shtaty Ameryki --- Zlucheni Derz͡havy --- ZSA --- Influenzavirus A --- Grippe porcine --- Aspect génétique --- Aspect génétique
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Avian influenza --- Avian influenza A virus --- Swine --- Avian influenza A virus. --- Pathogenesis --- Genetics --- Genetics. --- United States. --- Domestic pig --- Hogs --- Pig --- Pig farming --- Pigs --- Sus domestica --- Sus domesticus --- Sus scrofa domestica --- Sus scrofa domesticus --- Livestock --- Sus --- Avian orthomyxovirus type A --- Fowl plague virus --- Influenza A virus --- Poultry --- Avian flu --- Bird flu --- Fowl pest --- Fowl plague --- Influenza in birds --- Birds --- Influenza --- Viruses --- Virus diseases --- ABŞ --- ABSh --- Ameerika Ühendriigid --- America (Republic) --- Amerika Birlăshmish Shtatlary --- Amerika Birlăşmi Ştatları --- Amerika Birlăşmiş Ştatları --- Amerika ka Kelenyalen Jamanaw --- Amerika Qūrama Shtattary --- Amerika Qŭshma Shtatlari --- Amerika Qushma Shtattary --- Amerika (Republic) --- Amerikai Egyesült Államok --- Amerikanʹ Veĭtʹsėndi͡avks Shtattnė --- Amerikări Pĕrleshu̇llĕ Shtatsem --- Amerikas Forenede Stater --- Amerikayi Miatsʻyal Nahangner --- Ameriketako Estatu Batuak --- Amirika Carékat --- AQSh --- Ar. ha-B. --- Arhab --- Artsot ha-Berit --- Artzois Ha'bris --- Bí-kok --- Ē.P.A. --- É.-U. --- EE.UU. --- Egyesült Államok --- ĒPA --- Estados Unidos --- Estados Unidos da América do Norte --- Estados Unidos de América --- Estaos Xuníos --- Estaos Xuníos d'América --- Estatos Unitos --- Estatos Unitos d'America --- Estats Units d'Amèrica --- Ètats-Unis d'Amèrica --- États-Unis d'Amérique --- ÉU --- Fareyniḳṭe Shṭaṭn --- Feriene Steaten --- Feriene Steaten fan Amearika --- Forente stater --- FS --- Hēnomenai Politeiai Amerikēs --- Hēnōmenes Politeies tēs Amerikēs --- Hiwsisayin Amerikayi Miatsʻeal Tērutʻiwnkʻ --- Istadus Unidus --- Jungtinės Amerikos valstybės --- Mei guo --- Mei-kuo --- Meiguo --- Mî-koet --- Miatsʻyal Nahangner --- Miguk --- Na Stàitean Aonaichte --- NSA --- S.U.A. --- SAD --- Saharat ʻAmērikā --- SASht --- Severo-Amerikanskie Shtaty --- Severo-Amerikanskie Soedinennye Shtaty --- Si͡evero-Amerikanskīe Soedinennye Shtaty --- Sjedinjene Američke Države --- Soedinennye Shtaty Ameriki --- Soedinennye Shtaty Severnoĭ Ameriki --- Soedinennye Shtaty Si͡evernoĭ Ameriki --- Spojené obce severoamerické --- Spojené staty americké --- SShA --- Stadoù-Unanet Amerika --- Stáit Aontaithe Mheiriceá --- Stany Zjednoczone --- Stati Uniti --- Stati Uniti d'America --- Stâts Unîts --- Stâts Unîts di Americhe --- Steatyn Unnaneysit --- Steatyn Unnaneysit America --- SUA --- Sŭedineni amerikanski shtati --- Sŭedinenite shtati --- Tetã peteĩ reko Amérikagua --- U.S. --- U.S.A. --- United States of America --- Unol Daleithiau --- Unol Daleithiau America --- Unuiĝintaj Ŝtatoj de Ameriko --- US --- USA --- Usono --- Vaeinigte Staatn --- Vaeinigte Staatn vo Amerika --- Vereinigte Staaten --- Vereinigte Staaten von Amerika --- Verenigde State van Amerika --- Verenigde Staten --- VS --- VSA --- Wááshindoon Bikéyah Ałhidadiidzooígíí --- Wilāyāt al-Muttaḥidah --- Wilāyāt al-Muttaḥidah al-Amirīkīyah --- Wilāyāt al-Muttaḥidah al-Amrīkīyah --- Yhdysvallat --- Yunaeted Stet --- Yunaeted Stet blong Amerika --- ZDA --- Združene države Amerike --- Zʹi͡ednani Derz͡havy Ameryky --- Zjadnośone staty Ameriki --- Zluchanyi͡a Shtaty Ameryki --- Zlucheni Derz͡havy --- ZSA --- Grippe aviaire --- Influenzavirus A aviaire --- Porcs --- Pathogenèse --- Génétique
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