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Dissertation
Perinatal brain damage : possible therapeutic approaches to hypoxic-ischemic cerebral injury, studied in fetal animals
Authors: ---
ISBN: 3832209433 Year: 2003 Publisher: Aachen Shaker

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Book
Pathologie neurologique périnatale et ses conséquences
Authors: ---
ISSN: 16226666 ISBN: 9782294708954 2294708954 Year: 2010 Publisher: Issy-les-Moulineaux: Elsevier,


Book
Hypoxia in cancer : significance and impact on cancer therapy
Authors: ---
ISBN: 9819903130 9819903122 Year: 2023 Publisher: Singapore : Springer,

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Abstract

This book reviews the central role of hypoxia in cancer initiation and progression. It discusses the mechanisms of hypoxia in chemoresistance, radioresistance, angiogenesis, vasculogenesis, metastasis, metabolic, and genomic instability. It also explores the potential of hypoxia in the diagnosis and treatment of cancer. The book provides an overview of hypoxia imaging, its biological relevance, and mechanism of action. It helps in understanding the molecular mechanisms of the regulation of senescence by hypoxia. It explores the contribution of hypoxia to immune resistance and immune suppression/tolerance and determines the hypoxia-responsive long non-coding RNAs in regulating hypoxic gene expression at chromatin, transcriptional, and post-transcriptional levels. Further, it presents the functional link between hypoxia and miRNA expressions and hypoxia-regulated miRNAs in cancer cell survival in a low oxygen environment. Lastly, it discusses the applications of tumor-on-a-chip technology for the understanding of hypoxia-tumor microenvironment. This book is a valuable source for oncologists and scientists working to understand the role of hypoxia in cancer and therapeutic approaches.

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