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Transplantation, homologous --- Host vs graft reaction --- Skin --- Skin --- Transplantation --- Transplantation --- Transplantation, homologous --- Host vs graft reaction --- Skin --- Skin --- Transplantation --- Transplantation
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Blood bactericidal activity. --- Cardiopulmonary bypass. --- Hemostasis --- Host vs graft reaction. --- Surgical wound infection --- Drug effects. --- Immunology.
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Cardiopulmonary Bypass --- Hemostasis --- Blood Bactericidal Activity --- Surgical Wound Infection --- Host vs Graft Reaction --- drug effects --- immunology
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Cell transplantation. --- Transplantation immunology. --- Transplantation of organs, tissues, etc. --- Transplantation Immunology --- Host vs Graft Reaction --- Immunosuppression --- Organ Transplantation --- immunology. --- trends. --- physiology. --- Transplantation (chirurgie) --- Immunologie de transplantation.
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Mycophenolic acid --- Transplantation of organs, tissues, etc --- Immunotherapy --- Immunologic Factors --- Therapeutics --- Host vs Graft Reaction --- Investigative Techniques --- Fatty Acids --- Caproates --- Transplantation --- Immunologic Techniques --- Acids, Acyclic --- Transplantation Immunology --- Physiological Effects of Drugs --- Diagnostic Techniques and Procedures. --- Surgical Procedures, Operative --- Immunomodulation --- Lipids --- Pharmacologic Actions --- Biological Therapy --- Carboxylic Acids --- Organic Chemicals --- Immune System Phenomena --- Chemical Actions and Uses --- Mycophenolic Acid --- Immunosuppression Therapy --- Immunosuppressive Agents --- Organ Transplantation --- Graft Rejection --- Methods --- Drug Therapy --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Complications
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Mycophenolic acid --- Transplantation of organs, tissues, etc --- Immunotherapy --- Immunologic Factors --- Therapeutics --- Host vs Graft Reaction --- Investigative Techniques --- Fatty Acids --- Caproates --- Transplantation --- Immunologic Techniques --- Acids, Acyclic --- Transplantation Immunology --- Physiological Effects of Drugs --- Diagnostic Techniques and Procedures. --- Surgical Procedures, Operative --- Immunomodulation --- Lipids --- Pharmacologic Actions --- Biological Therapy --- Carboxylic Acids --- Organic Chemicals --- Immune System Phenomena --- Chemical Actions and Uses --- Mycophenolic Acid --- Immunosuppression Therapy --- Immunosuppressive Agents --- Organ Transplantation --- Graft Rejection --- Methods --- Drug Therapy --- Complications
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Mycophenolic acid --- Transplantation of organs, tissues, etc --- Immunotherapy --- Immunologic Factors --- Therapeutics --- Host vs Graft Reaction --- Investigative Techniques --- Fatty Acids --- Caproates --- Transplantation --- Immunologic Techniques --- Acids, Acyclic --- Transplantation Immunology --- Physiological Effects of Drugs --- Diagnostic Techniques and Procedures. --- Surgical Procedures, Operative --- Immunomodulation --- Lipids --- Pharmacologic Actions --- Biological Therapy --- Carboxylic Acids --- Organic Chemicals --- Immune System Phenomena --- Chemical Actions and Uses --- Mycophenolic Acid --- Immunosuppression Therapy --- Immunosuppressive Agents --- Organ Transplantation --- Graft Rejection --- Methods --- Drug Therapy --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Complications
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Mycophenolic acid --- Transplantation of organs, tissues, etc --- Immunotherapy --- Immunologic Factors --- Therapeutics --- Host vs Graft Reaction --- Investigative Techniques --- Fatty Acids --- Caproates --- Transplantation --- Immunologic Techniques --- Acids, Acyclic --- Transplantation Immunology --- Physiological Effects of Drugs --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Surgical Procedures, Operative --- Immunomodulation --- Lipids --- Pharmacologic Actions --- Chemicals and Drugs --- Biological Therapy --- Carboxylic Acids --- Organic Chemicals --- Immune System Phenomena --- Chemical Actions and Uses --- Phenomena and Processes --- Mycophenolic Acid --- Immunosuppression Therapy --- Immunosuppressive Agents --- Organ Transplantation --- Graft Rejection --- Methods --- Drug Therapy --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Complications --- Diagnostic Techniques and Procedures.
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This book collects salient observational data, derived predominantly from human studies, regarding the mechanism(s) of rejection in various pathologic conditions; the premise is that immune rejection, better defined as “immune-mediated, tissue-specific destruction” (TSD), comprises a broad range of phenomena ranging from tumor regression, to clearance of pathogen through destruction of infected cells, autoimmunity, allograft rejection by the host and host versus graft reactions. Like different hands can turn on or off a switch, distinct mechanisms can trigger TSD; however, a convergent pathway is ultimately observed when TSD occurs consisting of a dramatic switch from chronic to acute inflammation leading to the activation of a restricted number of genes that we comprise in the immunologic constant of rejection (ICR) model. Although the ICR model does not address “why” rejection occurs but rather “how”, and it may not contribute an explanation for the determinism of rejection, it provides, if correct, a simplified road map about the convergent pathways leading to TSD. This offers the opportunity to identify a common target for immune manipulation with therapeutic purposes since ICR-related pathways are restricted in expression to the tissues in which TSD occurs while are shut off in the rest of a normal organism. The book includes chapters from outstanding basic and/or observational scientists that have contributed to this area either by defining mechanisms relevant to the understanding of the inflammatory switch or by describing how this occurs in human tissues under different pathological conditions. We would like to entice our reader(s) to test with us, through, the readings, whether our hypothesis is correct; we predict that common themes will emerge particularly if attention will be paid to the general phenomenon of TSD rather than the peculiarities of individual pathologies. With the hope of having contributed with this book something novel and important and we wish our reader a pleasant journey in the wondrous land of immune-mediated, tissue-specific destruction.
Immunology --- Immunosuppressive agents --- Neoplastic Processes --- Immune System Diseases --- Host vs Graft Reaction --- Hypersensitivity --- Remission, Spontaneous --- Models, Biological --- Transplantation Immunology --- Neoplasms --- Diseases --- Models, Theoretical --- Pathologic Processes --- Biological Processes --- Neoplasm Regression, Spontaneous --- Autoimmune Diseases --- Hypersensitivity, Delayed --- Graft Rejection --- Models, Immunological --- Investigative Techniques --- Immune System Processes --- Biological Phenomena --- Pathological Conditions, Signs and Symptoms --- Phenomena and Processes --- Immune System Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Medicine --- Biology --- Health & Biological Sciences --- Oncology --- Microbiology & Immunology --- Immunology. --- Immunosuppressive agents. --- Immunosuppressant agents --- Immunosuppressants --- Immunosuppressive drugs --- Immunobiology --- Medicine. --- Cancer research. --- Biomedicine. --- Cancer Research. --- Drugs --- Immunopharmacology --- Life sciences --- Serology --- Oncology. --- Tumors --- Cancer research
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