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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Drug discovery --- Infectious Disease --- Anti-Virulence --- Anti-Infectives --- Host-Microbe Interactions

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This volume discusses the interactions between viruses and their host cells, and explores the roles of host and viral genes and non-coding RNAs in the virus replication cycle. During infection, viruses express a variety of genes, encoding proteins and RNAs that serve to subjugate the cell – by redirecting cellular processes to support viral replication and, at the same time, by mitigating the cellular response to infection. In this book, experts discuss these interactions in depth, and elaborate on our current understanding of virus-cell interactions for a diverse range of viruses, including positive and negative sense RNA viruses, DNA viruses, and a vector-borne virus. The roles of non-coding RNAs are also discussed. While each class of viruses has distinct replication requirements, this volume reveals unique features and commonalities in viral replication cycles. Accordingly, it represents a valuable source of information for researchers and clinicians alike.

Viral genetics --- Virus genetics --- Viruses --- Microbial genetics --- Mathematical models. --- Genetics --- Medical virology. --- Emerging infectious diseases. --- Virology. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Medical microbiology --- Virology --- Virus diseases --- RNA, Untranslated --- Virus Replication --- Host Microbial Interactions --- Virus Diseases --- genetics --- Bacteria Host Interactions --- Bacterial-Host Interactions --- Bacterium-Host Interactions --- Host Bacteria Interactions --- Host Microbe Interactions --- Host Microbiota Interactions --- Host Virus Interactions --- Host-Fungal Interactions --- Host-Microbial Interface --- Microbe Host Interactions --- Microbial Host Interactions --- Microbiota Host Interactions --- Viral-Host Interactions --- Virus Host Interactions --- Bacteria Host Interaction --- Bacterial Host Interactions --- Bacterial-Host Interaction --- Bacterium Host Interactions --- Bacterium-Host Interaction --- Host Bacteria Interaction --- Host Fungal Interactions --- Host Microbe Interaction --- Host Microbial Interaction --- Host Microbial Interface --- Host Microbiota Interaction --- Host Virus Interaction --- Host-Fungal Interaction --- Host-Microbial Interfaces --- Microbe Host Interaction --- Microbial Host Interaction --- Microbiota Host Interaction --- Viral Host Interactions --- Viral-Host Interaction --- Virus Host Interaction --- Noncoding RNA --- RNA, Non-Coding --- RNA, Non-Peptide-Coding --- RNA, Non-Protein-Coding --- RNA, Noncoding --- RNA, Nontranslated --- npcRNA --- Non-Coding RNA --- Non-Peptide-Coding RNA --- Non-Protein-Coding RNA --- Nontranslated RNA --- RNA, Non Coding --- RNA, Non Peptide Coding --- RNA, Non Protein Coding --- Untranslated RNA --- Infectious diseases. --- Microbiology