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Endocrine glands --- Hormone resistance. --- Hormone --- Diseases. --- physiology.
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Insulin resistance. --- Insulin tolerance --- Resistant diabetes --- Resistance to insulin --- Diabetes --- Hormone resistance --- Insulin antibodies --- Complications
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Drug Resistance. --- Hormone resistance. --- Hormones --- Mutation. --- Receptors, Drug --- Syndrome. --- Physiology. --- Physiology.
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In Insulin Resistance: The Metabolic Syndrome X, outstanding investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia (Syndrome X) play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease-the so-called diseases of Western civilization-as well as polycystic ovary disease. Under the aegis of Gerald Reaven, the discoverer of Syndrome X, the distinguished authorities writing here detail for the first time the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Each author has been encouraged to present a point of view that reflects their unique insights. The first authoritative book on the subject, Insulin Resistance: The Metabolic Syndrome X illuminates the special importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome. Its thoughtful and detailed approach will make it an essential reference for basic and clinical researchers seeking to understand these critical phenomena.
Insulin Resistance. --- Insulin resistance. --- Endocrinology . --- Endocrinology. --- Internal medicine --- Hormones --- Insulin tolerance --- Resistant diabetes --- Resistance to insulin --- Diabetes --- Hormone resistance --- Insulin antibodies --- Complications
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Fatty liver. --- Insulin resistance. --- Insulin tolerance --- Resistant diabetes --- Resistance to insulin --- Diabetes --- Hormone resistance --- Insulin antibodies --- Fatty degeneration --- Liver --- Complications --- Diseases
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Insulin. --- Insulin resistance. --- Diabetes --- Hormone resistance --- Insulin antibodies --- Insulin tolerance --- Resistant diabetes --- Resistance to insulin --- Hormones --- Hypoglycemic agents --- Pancreas --- Proinsulin --- Complications --- Secretions
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Now in a revised and expanded second edition, this unique text presents topics related to insulin resistance in youth and its consequences across the lifespan. In the first section of the book examining epidemiology, the contributors review controversies over the definition of insulin resistance in children and what is known about how insulin resistance in youth differs from adults, the measurement of insulin resistance in youth in the research and clinical settings, and current knowledge regarding the epidemiology of insulin resistance in the pediatric population. The second section of the book explores pathophysiology, including current knowledge of the molecular, metabolic, and physiologic mechanisms of insulin resistance, the unique pathophysiology of pregnancy and puberty, the contributions of the prenatal and early childhood environment to the development of insulin resistance, and adipose and biochemical mediators. This section concludes with discussion of the relationship between insulin resistance and cardiovascular disease and liver disorders. A third section, new to this second edition, explores insulin resistance in unique models: intrauterine growth restriction and girls with polycystic ovary syndrome and metabolic syndrome. The final section of the book explores the concepts of treatment through medications directed at insulin sensitivity, as well as exercise, weight loss medications and consequences of bariatric surgery. Insulin Resistance: Childhood Precursors of Adult Disease, Second Edition provides up-to-date reviews of all of these areas, providing the reader with a current perspective on issues in insulin resistance in youth, an emerging risk factor for disease across the lifespan, that will spur continued interest in the topic on the part of clinicians and researchers, perhaps promoting new points of view and creative approaches to this daunting challenge.
Endocrinology . --- Diabetes. --- Pediatrics. --- Endocrinology. --- Paediatrics --- Pediatric medicine --- Medicine --- Children --- Brittle diabetes --- Diabetes mellitus --- IDDM (Disease) --- Insulin-dependent diabetes --- Ketosis prone diabetes --- Type 1 diabetes --- Carbohydrate intolerance --- Endocrine glands --- Diabetic acidosis --- Glycosylated hemoglobin --- Internal medicine --- Hormones --- Diseases --- Health and hygiene --- Insulin resistance. --- Insulin tolerance --- Resistant diabetes --- Resistance to insulin --- Diabetes --- Hormone resistance --- Insulin antibodies --- Complications
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Insulin resistance. --- Nervous system --- Insulin Resistance --- Nervous System Diseases --- Diseases. --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- Neurology --- Insulin Sensitivity --- Resistance, Insulin --- Sensitivity, Insulin --- Donohue Syndrome --- Medical neurology --- Nerves --- Neurologic disorders --- Neurological disorders --- Neuropathology --- Insulin tolerance --- Resistant diabetes --- Resistance to insulin --- Diabetes --- Hormone resistance --- Insulin antibodies --- Diseases --- Complications
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The prevalence of disorders related to insulin resistance has continued to increase throughout the developed and developing world. The world’s population has continued to become more obese and sedentary. Of great concern in the last decade is the extension of these deleterious lifestyle patterns to the pediatric population, leading to both obesity and the appearance of insulin resistance-related disorders in youth as well as adults. Insulin Resistance: Childhood Precursors and Adult Disease presents topics related to insulin resistance and its consequences across the lifespan. In the first section of the book examining epidemiology, the contributors review controversies over the definition of metabolic syndrome in adults and children, current knowledge regarding the epidemiology of insulin resistance in the pediatric population and the contributions of the prenatal and early childhood environment to the development of insulin resistance. The Second part of the book explores pathophysiology, with reviews of the techniques used to study insulin resistance, as well as current knowledge of the molecular and physiologic mechanisms of insulin resistance, including the contributions of adipose tissue and biochemical mediators. This section concludes with discussion of the relationship between insulin resistance and cardiovascular, endothelial, liver and gonadal disorders. The final section of the book explores the impact of exercise and weight loss medications on insulin resistance. Insulin resistance is likely to be the most important public health concern in many parts of the world in coming decades. This volume provides up-to-date reviews of these areas, providing the reader with a current perspective on issues in insulin resistance as they affect patients across the lifespan. The hope for Insulin Resistance: Childhood Precursors and Adult Disease is that it will spur continued interest in the topic on the part of clinicians and researchers, perhaps promoting new points of view and creative approaches to a daunting challenge.
Medicine & Public Health. --- Endocrinology. --- Internal Medicine. --- General Practice / Family Medicine. --- Pediatrics. --- Cardiology. --- Medicine. --- Family medicine. --- Internal medicine. --- Médecine --- Médecine familiale --- Médecine interne --- Cardiologie --- Endocrinologie --- Pédiatrie --- Diabetes -- Diet therapy. --- Health. --- Insulin resistance. --- Non-insulin-dependent diabetes. --- Insulin resistance --- Insulin Resistance --- Drug Resistance --- Hyperinsulinism --- Glucose Metabolism Disorders --- Pharmacological Phenomena --- Physiological Phenomena --- Metabolic Diseases --- Nutritional and Metabolic Diseases --- Phenomena and Processes --- Diseases --- Clinical Endocrinology --- Medicine --- Health & Biological Sciences --- Insulin tolerance --- Resistant diabetes --- Resistance to insulin --- General practice (Medicine). --- Diabetes. --- Diabetes --- Hormone resistance --- Insulin antibodies --- Complications --- Heart --- Internal medicine --- Paediatrics --- Pediatric medicine --- Children --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Medicine, Internal --- Hormones --- Brittle diabetes --- Diabetes mellitus --- IDDM (Disease) --- Insulin-dependent diabetes --- Ketosis prone diabetes --- Type 1 diabetes --- Carbohydrate intolerance --- Endocrine glands --- Diabetic acidosis --- Glycosylated hemoglobin --- Health and hygiene --- Endocrinology .
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Over the past 50 years, there has been a dramatic increase in the prevalence of interrelated metabolic disease states, including obesity, insulin resistance, and type 2 diabetes mellitus. In modern Western nations, the population-based prevalence of insulin resistance is approaching 20%, and type 2 diabetes is now the most common endocrine disorder in adults. No longer a disease reserved for the aging population, type 2 diabetes is also on the rise in adolescents. Approximately 30% of all newly diagnosed cases (between 1982 and 1994 in the United States alone) are among people 10 to 19 years of age.For those engaged in a struggle against this modern-day epidemic, Physical Activity and Type 2 Diabetes provides cutting-edge research to energize current efforts in diabetes prevention, management, and treatment. The most in-depth and up-to-date book on the topic, Physical Activity and Type 2 Diabetes presents a series of independent but related chapters authored by the foremost researchers of insulin resistance examining topics such as these : -Physical inactivity as a primary cause for the rising incidence of insulin resistance -The emergence of an "exercise-deficient" phenotype -The effects of exercise training on selected aspects of substrate metabolism -The role of endurance and resistance training programs for the prevention and treatment of insulin resistance -The identification of new molecular targets and pathways useful for the treatment of insulin resistance and type 2 diabetes. Physical Activity and Type 2 Diabetes provides a four-part, in-depth examination of the relational nature of diabetes and physical activity. Part I begins with a description of the scope and extent of the "diabesity" epidemic. The risk factors for diabetes, the underlying causes of the epidemic, and its potential consequences are outlined as well as the role of physical inactivity in the pathogenesis of diabetes and plans for preventive exercise biology. Part II continues with an examination of some of the major defects of substrate metabolism in individuals with insulin resistance, while in part III the authors discuss the impact of exercise interventions in the prevention, management, and treatment of type 2 diabetes. Part IV presents recent developments in molecular and cellular biology that may provide treatment therapies for the prevention of type 2 diabetes. Based on extensive research, Physical Activity and Type 2 Diabetes presents a wealth of information to assist the biomedical and research community in creating prescriptive therapeutic tools for type 2 diabetes intervention--and offers hope for the alleviation of the global epidemic of insulin resistance.
Diabetes Mellitus, Type 2 --- Exercise. --- Insulin Resistance --- Diabetes --- Insulin resistance --- Diabète --- Insulinorésistance --- prevention & control. --- physiology. --- Exercise therapy. --- Prevention. --- Kinésithérapie --- Thérapeutique par l'exercice --- Prévention --- Exercise therapy --- Prevention --- prevention and control --- physiology --- 61:796 --- 612:796 --- 616.379-008.64 --- 796.034 --- 615.825 --- Sportgeneeskunde --- Fysiologie van de sport --- Diabetes mellitus --- Aangepast sporten. Adapted physical activity --- Revalidatie door beweging. Mechanotherapie --- 796.034 Aangepast sporten. Adapted physical activity --- 616.379-008.64 Diabetes mellitus --- 612:796 Fysiologie van de sport --- 61:796 Sportgeneeskunde --- Diabète --- Insulinorésistance --- Kinésithérapie --- Thérapeutique par l'exercice --- Prévention --- Insulin tolerance --- Resistant diabetes --- Resistance to insulin --- Hormone resistance --- Insulin antibodies --- Brittle diabetes --- IDDM (Disease) --- Insulin-dependent diabetes --- Ketosis prone diabetes --- Type 1 diabetes --- Carbohydrate intolerance --- Endocrine glands --- Diabetic acidosis --- Glycosylated hemoglobin --- Complications --- Diseases
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