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Following on from the highly successful inaugural 2011 conference which took place in Switzerland, Endocrine Disruptors 2012 addressed key topics related to the evaluation of adverse effects on the endocrine system and corresponding regulatory requirements. These proceedings contain all the presentations from this conference which brought together experts from academia, government, and industry from around the globe to focus on current and future trends in testing, interpretation and evaluation of test results and how this relates to or influences regulatory activities.
Endocrine disrupting chemicals --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants
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"Wide variety of pesticides and other synthetic chemicals may disrupt the normal function of the endocrine system, cause alteration and also attack the immune system of humans and wildlife at very low concentration levels. Chapter one of this book provides an overview of analytical methods, including sample preparation steps, chromatographic separation and detection of endocrine disrupting pesticides in a variety of food, environmental and biological matrices. Chapter two studies endocrine disrupting compound (EDC) exposure from recycled wastewater compared to other water related risks in developed and developing nations. Chapter three summarizes the role of EDCs on pregnancy and birth outcomes, included but not limited to fertility problems, premature birth, low birth weight, and miscarriage along with in-vitro, animal, and epidemiological studies. In the last chapter, the worst EDCs will be revealed and their related potential hazardous health risks to humans are discussed. Furthermore, suggestions to help the reader avoid such toxic chemicals are presented"--
Endocrine disrupting chemicals. --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants
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These proceedings cover all the presentations from iSmithers' inaugural Endocrine Disruptors 2011 conference which addressed key topics related to the evaluation of adverse effects on the endocrine system and corresponding regulatory requirements.
Endocrine disrupting chemicals --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants
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Discussions regarding regulation of endocrine disruptors (EDs) and combination effects are ongoing in Europe. Among the central topics of discussion are establishment of criteria for identification of EDs, whether there is a threshold for endocrine disrupting effects and how EDs should be handled within relevant EU regulations. In addition, a roadmap for further EU work regarding combination effects has been presented, but more detailed discussions are needed regarding scientific issues and regulatory intervention. Possible Member State initiatives to provide input to these EU processes were discussed in a Nordic workshop held in Oslo in November 2013. This report describes the workshop presentations, initiatives and thoughts from each of the Nordic countries, the plenary discussions, and the main workshop outcomes.
Endocrine disrupting chemicals. --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants
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In 1941 the Food and Drug Administration approved the use of diethylstilbestrol (DES), the first synthetic chemical to be marketed as an estrogen and one of the first to be identified as a hormone disruptor-a chemical that mimics hormones. Although researchers knew that DES caused cancer and disrupted sexual development, doctors prescribed it for millions of women, initially for menopause and then for miscarriage, while farmers gave cattle the hormone to promote rapid weight gain. Its residues, and those of other chemicals, in the American food supply are changing the internal ecosystems of human, livestock, and wildlife bodies in increasingly troubling ways. In this gripping exploration, Nancy Langston shows how these chemicals have penetrated into every aspect of our bodies and ecosystems, yet the U.S. government has largely failed to regulate them and has skillfully manipulated scientific uncertainty to delay regulation. Personally affected by endocrine disruptors, Langston argues that the FDA needs to institute proper regulation of these commonly produced synthetic chemicals.
Endocrine disrupting chemicals --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants --- History. --- Government policy --- Endocrine Disruptors --- Environmental Exposure --- History, 20th Century --- History, 21st Century --- Adverse effects --- History
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"Provides readers with access to a range of information from the basic mechanisms and assays through to cutting-edge research investigating concerns for human health Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations Newly added content on topics like low-term, low dose mixtures, windows of susceptibility to EDCs, EDCs effect on the gut microbiome, green chemistry, and nanotechnology"--
Endocrine disrupting chemicals. --- Endocrine disrupting chemicals --- Environmental aspects. --- Health aspects. --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants
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Environmental Contaminants and Endocrine Health focuses specifically on contaminants with hormonal disrupting activities. The book provides insights into the multiple effects of endocrine-disrupting chemicals (EDCs) and their mechanism of action (MoA) on metabolism, reproduction and the multiple physiological roles of the endocannabinoid system which has recently been indicated as new target. The content systematically covers EDC sources and effects, EDCs as sources of disease and health impairment in laboratory models, EDCs as the cause of disease and health impairment in humans and wild species, and the removal of hazardous pollutants from wastewaters to highlight intervention, mitigation and adaptation for reduced threat.
Endocrine disrupting chemicals. --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants --- Endocrine disrupting chemicals --- Endocrine Disruptors --- Environmental Pollutants --- Environmental aspects.
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Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human healthPresents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human healthOffers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations.--
Endocrine disrupting chemicals -- Health aspects. --- Endocrine disrupting chemicals. --- Endocrine toxicology. --- Endocrine disrupting chemicals --- Physiological Effects of Drugs --- Environmental Pollutants --- Pharmacologic Actions --- Toxic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Endocrine Disruptors --- Public Health --- Health & Biological Sciences --- Toxicology & Public Health --- Health aspects --- Health aspects. --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants
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Animal behavior --- Animal communication. --- Endocrine disrupting chemicals. --- Endocrine aspects. --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants --- Animal biocommunication --- Animal language --- Biocommunication, Animal --- Language learning by animals --- Animal behavioral endocrinology --- Animal hormone-behavior relationships --- Behavioral endocrinology, Animal --- Hormonal aspects of animal behavior --- Hormone-behavior relationships, Animal --- Interactions, Animal hormone-behavior --- Relationships, Animal hormone-behavior --- Endocrinology --- Hormonal aspects
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The rise in the incidence of health problems such as reproductive disorders and testicular and breast cancer has been linked by some to endocrine disrupting chemicals in the environment. The role of food in transmitting these chemicals is uncertain and a topic of considerable research. This important book addresses key topics in this area.The first part of the book reviews the impacts of endocrine disrupting chemicals on health and behaviour, with chapters on the effect of dietary endocrine disruptors in such areas as the developing foetus, cancer and bone health. Parts two and three f
Endocrine disrupting chemicals. --- Food --- Food contamination. --- Contaminated food --- Foods, Contaminated --- Contamination (Technology) --- Food adulteration and inspection --- Analysis of food --- Chemistry of food --- Food, Chemistry of --- Food chemistry --- Chemistry, Technical --- Sanitary chemistry --- Disrupters, Endocrine --- Disrupting chemicals, Endocrine --- Disruptors, Endocrine --- EDCs (Endocrine disrupting chemicals) --- Endocrine disrupters --- Endocrine disrupting compounds --- Endocrine disruptors --- Environmental endocrine disrupters --- Environmental endocrine disrupting chemicals --- Environmental endocrine disruptors --- Hormone disruptors --- Pollutants --- Analysis. --- Contamination --- Chemistry --- Composition
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