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Huntington's disease --- Chorea. --- Huntington Disease. --- Reference Books, Medical. --- Huntington's chorea --- -Academic collection --- Chronic progressive chorea --- Chronic progressive hereditary chorea --- Degenerative chorea --- HC (Disease) --- HD (Disease) --- Hereditary chorea --- Huntington chorea --- Huntington chronic progressive hereditary chorea --- Huntington disease --- Lund-Huntington chorea --- Microcellular striatal syndrome --- Progressive hereditary chorea, Chronic --- Chorea --- Dementia --- Genetic disorders --- Nervous system --- Books, Medical Reference --- Medical Reference Books --- Akinetic-Rigid Variant of Huntington Disease --- Chorea, Chronic Progressive Hereditary (Huntington) --- Chronic Progressive Hereditary Chorea (Huntington) --- Huntington Chronic Progressive Hereditary Chorea --- Huntington Disease, Akinetic-Rigid Variant --- Huntington Disease, Juvenile --- Huntington Disease, Juvenile-Onset --- Huntington Disease, Late Onset --- Huntington's Chorea --- Huntington's Disease --- Juvenile-Onset Huntington Disease --- Late-Onset Huntington Disease --- Progressive Chorea, Chronic Hereditary (Huntington) --- Progressive Chorea, Hereditary, Chronic (Huntington) --- Huntington Chorea --- Juvenile Huntington Disease --- Akinetic Rigid Variant of Huntington Disease --- Chorea, Huntington --- Chorea, Huntington's --- Huntington Disease, Akinetic Rigid Variant --- Huntington Disease, Juvenile Onset --- Huntington Disease, Late-Onset --- Juvenile Onset Huntington Disease --- Late Onset Huntington Disease --- Chorea Disorders --- Chorea Syndromes --- Chorea, Benign Hereditary --- Chorea, Chronic Progressive --- Chorea, Rheumatic --- Chorea, Senile --- Chorea, Sydenham --- Choreatic Syndromes --- Choreic Movement --- Dyskinesias, Paroxysmal --- Hereditary Chorea --- Hereditary Progressive Chorea Without Dementia --- Paroxysmal Dyskinesias --- Rheumatic Chorea --- Senile Chorea --- St. Vitus's Dance --- Sydenham Chorea --- Sydenham's Chorea --- Choreatic Disorders --- Choreiform Movement --- Benign Hereditary Chorea --- Benign Hereditary Choreas --- Chorea Disorder --- Chorea Syndrome --- Chorea, Hereditary --- Chorea, Sydenham's --- Choreas --- Choreas, Benign Hereditary --- Choreas, Chronic Progressive --- Choreas, Hereditary --- Choreas, Rheumatic --- Choreas, Senile --- Choreas, Sydenham --- Choreatic Disorder --- Choreatic Syndrome --- Choreic Movements --- Choreiform Movements --- Chronic Progressive Chorea --- Chronic Progressive Choreas --- Disorder, Chorea --- Disorder, Choreatic --- Disorders, Chorea --- Disorders, Choreatic --- Dyskinesia, Paroxysmal --- Hereditary Chorea, Benign --- Hereditary Choreas --- Hereditary Choreas, Benign --- Movement, Choreic --- Movement, Choreiform --- Movements, Choreic --- Movements, Choreiform --- Paroxysmal Dyskinesia --- Progressive Chorea, Chronic --- Progressive Choreas, Chronic --- Rheumatic Choreas --- Senile Choreas --- St. Vitus Dance --- St. Vitus's Dances --- St. Vituss Dance --- Sydenham Choreas --- Sydenhams Chorea --- Syndrome, Chorea --- Syndrome, Choreatic --- Syndromes, Chorea --- Syndromes, Choreatic --- Bibliography --- Degeneration --- Bibliography. --- Huntington Disease --- Reference Books, Medical --- Academic collection --- 016 : 616.851 "1872 : 1972" --- Huntington's disease - Bibliography

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Motor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research occurred in 1993, with the identification of the gene causing this devastating monogenetic illness. Since 1996, several genes were reported to cause familial forms of PD. Following these genetic discoveries, a variety of genetic disease models were generated, providing completely novel opportunities to explore the neurobiological basis of HD and PD. Genetic models allow us to study the earliest manifestations of the diseases both behaviorally and neuropathologically, and provide tools to probe molecular pathways of neurodegeneration. Additionally, neurotoxic animal models allow us to reproduce neurochemical and cellular events of great pathophysiological importance. In the PD field, neurotoxic animal models remain the preferred option to reproduce symptomatic features of the human disease that are responsive to dopaminergic pharmacotherapies. In addition, neurotoxic PD models are often used to investigate pathways of mitochondrial dysfunction, oxidative stress, and neuroinflammation. This book provides up-to-date reviews on current animal models of both HD and PD. These animal models are essential to investigate links between the pathobiology and the behavioral abnormalities associated with these disorders.

Biomedicine. --- Neurosciences. --- Human Genetics. --- Neurobiology. --- Cell Biology. --- Medicine. --- Human genetics. --- Cytology. --- Médecine --- Génétique humaine --- Neurosciences --- Cytologie --- Neurobiologie --- Biology --- Parkinsonian Disorders --- Cognition Disorders --- Basal Ganglia Diseases --- Dementia --- Investigative Techniques --- Heredodegenerative Disorders, Nervous System --- Behavior --- Neurodegenerative Diseases --- Chorea --- Behavior and Behavior Mechanisms --- Delirium, Dementia, Amnestic, Cognitive Disorders --- Movement Disorders --- Biological Science Disciplines --- Brain Diseases --- Nervous System Diseases --- Dyskinesias --- Genetic Diseases, Inborn --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Central Nervous System Diseases --- Mental Disorders --- Psychiatry and Psychology --- Natural Science Disciplines --- Congenital, Hereditary, and Neonatal Diseases and Abnormalities --- Diseases --- Disciplines and Occupations --- Parkinson Disease --- Huntington Disease --- Behavior, Animal --- Models, Animal --- Neurobiology --- Medicine --- Health & Biological Sciences --- Neurology --- Neurobiology, Cellular --- Neurobiology, Molecular --- Cellular Neurobiology --- Molecular Neurobiology --- Experimental Animal Models --- Laboratory Animal Models --- Animal Model --- Animal Model, Experimental --- Animal Model, Laboratory --- Animal Models --- Animal Models, Experimental --- Animal Models, Laboratory --- Experimental Animal Model --- Laboratory Animal Model --- Model, Animal --- Model, Experimental Animal --- Model, Laboratory Animal --- Models, Experimental Animal --- Models, Laboratory Animal --- Animal Behavior --- Animal Behaviors --- Behaviors, Animal --- Akinetic-Rigid Variant of Huntington Disease --- Chorea, Chronic Progressive Hereditary (Huntington) --- Chronic Progressive Hereditary Chorea (Huntington) --- Huntington Chronic Progressive Hereditary Chorea --- Huntington Disease, Akinetic-Rigid Variant --- Huntington Disease, Juvenile --- Huntington Disease, Juvenile-Onset --- Huntington Disease, Late Onset --- Huntington's Chorea --- Huntington's Disease --- Juvenile-Onset Huntington Disease --- Late-Onset Huntington Disease --- Progressive Chorea, Chronic Hereditary (Huntington) --- Progressive Chorea, Hereditary, Chronic (Huntington) --- Huntington Chorea --- Juvenile Huntington Disease --- Akinetic Rigid Variant of Huntington Disease --- Chorea, Huntington --- Chorea, Huntington's --- Huntington Disease, Akinetic Rigid Variant --- Huntington Disease, Juvenile Onset --- Huntington Disease, Late-Onset --- Juvenile Onset Huntington Disease --- Late Onset Huntington Disease --- Idiopathic Parkinson's Disease --- Lewy Body Parkinson's Disease --- Parkinson Disease, Idiopathic --- Parkinson's Disease --- Parkinson's Disease, Idiopathic --- Parkinson's Disease, Lewy Body --- Idiopathic Parkinson Disease --- Lewy Body Parkinson Disease --- Paralysis Agitans --- Primary Parkinsonism --- Parkinsonism, Primary --- Disorders, Congenital --- Congenital Disorders --- Neonatal Diseases and Abnormalities --- Congenital Disorder --- Disorder, Congenital --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Behavior Disorders --- Diagnosis, Psychiatric --- Mental Disorders, Severe --- Psychiatric Diagnosis --- Disorder, Mental --- Disorder, Severe Mental --- Disorders, Behavior --- Disorders, Mental --- Disorders, Severe Mental --- Mental Disorder --- Mental Disorder, Severe --- Severe Mental Disorder --- Severe Mental Disorders --- CNS Diseases --- Central Nervous System Disorders --- CNS Disease --- Genetic Diseases --- Genetic Disorders --- Hereditary Disease --- Inborn Genetic Diseases --- Single-Gene Defects --- Hereditary Diseases --- Defect, Single-Gene --- Defects, Single-Gene --- Disease, Genetic --- Disease, Hereditary --- Disease, Inborn Genetic --- Diseases, Genetic --- Diseases, Hereditary --- Diseases, Inborn Genetic --- Disorder, Genetic --- Disorders, Genetic --- Genetic Disease --- Genetic Disease, Inborn --- Genetic Disorder --- Inborn Genetic Disease --- Single Gene Defects --- Single-Gene Defect --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- Brain Disorders --- CNS Disorders, Intracranial --- Central Nervous System Disorders, Intracranial --- Central Nervous System Intracranial Disorders --- Encephalon Diseases --- Encephalopathy --- Intracranial CNS Disorders --- Intracranial Central Nervous System Disorders --- Brain Disease --- Brain Disorder --- CNS Disorder, Intracranial --- Encephalon Disease --- Encephalopathies --- Intracranial CNS Disorder --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Movement Disorder Syndromes --- Oral Dyskinesia --- Dyskinesia Syndromes --- Etat Marbre --- Status Marmoratus --- Dyskinesia Syndrome --- Dyskinesia, Oral --- Dyskinesias, Oral --- Movement Disorder --- Movement Disorder Syndrome --- Oral Dyskinesias --- Nonpsychotic Organic Brain Syndrome --- Clerambault Syndrome --- Kandinsky Syndrome --- Mental Disorders, Organic --- Organic Brain Syndrome, Nonpsychotic --- Organic Mental Disorders --- Organic Mental Disorders, Psychotic --- Psychoses, Traumatic --- Disorder, Neurocognitive --- Disorders, Neurocognitive --- Disorders, Organic Mental --- Mental Disorder, Organic --- Neurocognitive Disorder --- Organic Mental Disorder --- Traumatic Psychoses --- Neuroscience --- Chorea Disorders --- Chorea Syndromes --- Chorea, Benign Hereditary --- Chorea, Chronic Progressive --- Chorea, Rheumatic --- Chorea, Senile --- Chorea, Sydenham --- Choreatic Syndromes --- Choreic Movement --- Dyskinesias, Paroxysmal --- Hereditary Chorea --- Hereditary Progressive Chorea Without Dementia --- Paroxysmal Dyskinesias --- Rheumatic Chorea --- Senile Chorea --- St. Vitus's Dance --- Sydenham Chorea --- Sydenham's Chorea --- Choreatic Disorders --- Choreiform Movement --- Benign Hereditary Chorea --- Benign Hereditary Choreas --- Chorea Disorder --- Chorea Syndrome --- Chorea, Hereditary --- Chorea, Sydenham's --- Choreas --- Choreas, Benign Hereditary --- Choreas, Chronic Progressive --- Choreas, Hereditary --- Choreas, Rheumatic --- Choreas, Senile --- Choreas, Sydenham --- Choreatic Disorder --- Choreatic Syndrome --- Choreic Movements --- Choreiform Movements --- Chronic Progressive Chorea --- Chronic Progressive Choreas --- Disorder, Chorea --- Disorder, Choreatic --- Disorders, Chorea --- Disorders, Choreatic --- Dyskinesia, Paroxysmal --- Hereditary Chorea, Benign --- Hereditary Choreas --- Hereditary Choreas, Benign --- Movement, Choreic --- Movement, Choreiform --- Movements, Choreic --- Movements, Choreiform --- Paroxysmal Dyskinesia --- Progressive Chorea, Chronic --- Progressive Choreas, Chronic --- Rheumatic Choreas --- Senile Choreas --- St. Vitus Dance --- St. Vitus's Dances --- St. Vituss Dance --- Sydenham Choreas --- Sydenhams Chorea --- Syndrome, Chorea --- Syndrome, Choreatic --- Syndromes, Chorea --- Syndromes, Choreatic --- Degenerative Diseases, Central Nervous System --- Degenerative Diseases, Neurologic --- Degenerative Diseases, Spinal Cord --- Degenerative Neurologic Diseases --- Degenerative Neurologic Disorders --- Nervous System Degenerative Diseases --- Neurodegenerative Disorders --- Neurologic Degenerative Conditions --- Neurologic Degenerative Diseases --- Neurologic Diseases, Degenerative --- Degenerative Diseases, Nervous System --- Degenerative Condition, Neurologic --- Degenerative Conditions, Neurologic --- Degenerative Neurologic Disease --- Degenerative Neurologic Disorder --- Neurodegenerative Disease --- Neurodegenerative Disorder --- Neurologic Degenerative Condition --- Neurologic Degenerative Disease --- Neurologic Disease, Degenerative --- Neurologic Disorder, Degenerative --- Neurologic Disorders, Degenerative --- Acceptance Process --- Acceptance Processes --- Behaviors --- Process, Acceptance --- Processes, Acceptance --- Degenerative Hereditary Diseases, Nervous System --- Hereditary Neurodegenerative Diseases --- Hereditary-Degenerative Disorders, Nervous System --- Nervous System Degenerative Hereditary Diseases --- Nervous System Hereditary Degenerative Diseases --- Degenerative Disease, Nervous System, Hereditary --- Degenerative Hereditary Disorders, Nervous System --- Hereditary Diseases, Neurodegenerative --- Nervous System Diseases, Degenerative, Hereditary --- Neurodegenerative Diseases, Hereditary --- Disease, Hereditary Neurodegenerative --- Disease, Neurodegenerative Hereditary --- Diseases, Hereditary Neurodegenerative --- Diseases, Neurodegenerative Hereditary --- Hereditary Degenerative Disorders, Nervous System --- Hereditary Disease, Neurodegenerative --- Hereditary Neurodegenerative Disease --- Neurodegenerative Disease, Hereditary --- Neurodegenerative Hereditary Disease --- Neurodegenerative Hereditary Diseases --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Amentia --- Familial Dementia --- Senile Paranoid Dementia --- Amentias --- Dementia, Familial --- Dementias --- Dementias, Familial --- Dementias, Senile Paranoid --- Familial Dementias --- Paranoid Dementia, Senile --- Paranoid Dementias, Senile --- Senile Paranoid Dementias --- Basal Ganglia Disorders --- Lenticulostriate Disorders --- Extrapyramidal Disorders --- Basal Ganglia Disease --- Basal Ganglia Disorder --- Extrapyramidal Disorder --- Lenticulostriate Disorder --- Overinclusion --- Disorder, Cognition --- Disorders, Cognition --- Autosomal Dominant Juvenile Parkinson Disease --- Autosomal Dominant Juvenile Parkinsonism --- Autosomal Dominant Parkinsonism --- Autosomal Recessive Juvenile Parkinson Disease --- Autosomal Recessive Parkinsonism --- Autosomal Recesssive Juvenile Parkinsonism --- Chromosome 6-Linked Autosomal Recessive Parkinsonism --- Experimental Parkinson Disease --- Experimental Parkinsonism --- Experimental Parkinsonism, MPTP-Induced --- Familial Parkinson Disease, Autosomal Recessive --- Juvenile Parkinson Disease --- Juvenile Parkinson Disease, Autosomal Dominant --- Juvenile Parkinson Disease, Autosomal Recessive --- Juvenile Parkinsonism, Autosomal Dominant --- Juvenile Parkinsonism, Autosomal Recessive --- MPTP-Induced Experimental Parkinsonism --- Parkinson Disease 2 --- Parkinson Disease 2, Autosomal Recessive Juvenile --- Parkinson Disease Autosomal Recessive, Early Onset --- Parkinson Disease, Autosomal Dominant. Juvenile --- Parkinson Disease, Experimental --- Parkinson Disease, Familial, Autosomal Recessive --- Parkinson Disease, Juvenile --- Parkinson Disease, Juvenile, Autosomal Dominant --- Parkinson Disease, Juvenile, Autosomal Recessive --- Parkinsonian Diseases --- Parkinsonian Syndromes --- Parkinsonism, Early Onset, with Diurnal Fluctuation --- Parkinsonism, Early-Onset, With Diurnal Fluctuation --- Parkinsonism, Juvenile, Autosomal Dominant --- Parkinsonism, Juvenile, Autosomal Recessive --- Familial Juvenile Parkinsonism --- Parkinsonian Syndrome --- Parkinsonism --- Parkinsonism, Experimental --- Parkinsonism, Juvenile --- Ramsay Hunt Paralysis Syndrome --- Chromosome 6 Linked Autosomal Recessive Parkinsonism --- Diseases, Experimental Parkinson --- Dominant Parkinsonism, Autosomal --- Experimental Parkinson Diseases --- Experimental Parkinsonism, MPTP Induced --- Experimental Parkinsonisms --- Juvenile Parkinsonism --- Juvenile Parkinsonism, Familial --- Juvenile Parkinsonisms --- MPTP Induced Experimental Parkinsonism --- Parkinson Diseases, Experimental --- Parkinsonism, Autosomal Dominant --- Parkinsonism, Autosomal Recessive --- Parkinsonism, Familial Juvenile --- Parkinsonism, MPTP-Induced Experimental --- Parkinsonisms, Experimental --- Parkinsonisms, Juvenile --- Recessive Parkinsonism, Autosomal --- Abnormal Movements --- Hemiballism --- Linguofacial Dyskinesia --- Oral-facial Dyskinesia --- Tardive Oral Dyskinesia --- Asterixis --- Ballismus --- Hemiballismus --- Involuntary Movements --- Lingual-Facial-Buccal Dyskinesia --- Orofacial Dyskinesia --- Abnormal Movement --- Dyskinesia --- Dyskinesia, Lingual-Facial-Buccal --- Dyskinesia, Linguofacial --- Dyskinesia, Oral-facial --- Dyskinesia, Orofacial --- Dyskinesias, Lingual-Facial-Buccal --- Dyskinesias, Linguofacial --- Dyskinesias, Oral-facial --- Dyskinesias, Orofacial --- Involuntary Movement --- Lingual Facial Buccal Dyskinesia --- Lingual-Facial-Buccal Dyskinesias --- Linguofacial Dyskinesias --- Movement, Abnormal --- Movement, Involuntary --- Movements, Abnormal --- Movements, Involuntary --- Oral facial Dyskinesia --- Oral-facial Dyskinesias --- Orofacial Dyskinesias --- Tardive Oral Dyskinesias --- Cell biology. --- Neural sciences --- Neurological sciences --- Medical sciences --- Nervous system --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Huntington's disease. --- Parkinson's disease. --- Diseases. --- Chronic progressive chorea --- Chronic progressive hereditary chorea --- Degenerative chorea --- HC (Disease) --- HD (Disease) --- Hereditary chorea --- Huntington chorea --- Huntington chronic progressive hereditary chorea --- Huntington disease --- Huntington's chorea --- Lund-Huntington chorea --- Microcellular striatal syndrome --- Progressive hereditary chorea, Chronic --- Genetic disorders --- Medical neurology --- Nerves --- Neurologic disorders --- Neurological disorders --- Neuropathology --- Palsy, Shaking --- Paralysis agitans --- Parkinson disease --- Shaking palsy --- Brain --- Extrapyramidal disorders --- Degeneration