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Hepacivirus --- drug effects --- Hepacivirus --- drug effects

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Hepatitis C --- Hepatitis C --- Hepatitis C virus --- Hepatitis C --- Hepatitis C --- Hepatitis C --- Hepacivirus. --- Interferon-alpha --- Treatment --- diagnosis. --- drug therapy. --- epidemiology. --- therapeutic use.

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Milieu des années 1970. Une maladie du foie inconnue fait son apparition, probablement virale, qui n'est ni une hépatite A, ni une hépatite B. D'abord jugés bénins, les symptômes se font vite inquiétants. Malgré tous les efforts de la communauté médicale et scientifique mondiale, le virus demeure invisible et se propage... Quarante ans plus tard, démasqué, il vit ses derniers moments. Aujourd'hui, l'hépatite C peut être guérie à presque cent pour cent. Des patients qui ont souffert de la maladie aux médecins et aux scientifiques qui l'ont vaincue, cet ouvrage met en scène les principaux acteurs de cette fulgurante histoire. Un peu moins de cent mille malades restent à soigner en France. Après cette ultime bataille, la dernière heure de l'hépatite C aura enfin sonné dans l'Hexagone. Et bientôt partout dans le monde ? (source : 4e de couverture)

Hepatitis C --- Hepatitis C virus --- Hepacivirus --- Hépatite C --- Virus de l'hépatite C. --- Hepacivirus. --- Histoire du 20ème siècle. --- Histoire du 21ème siècle. --- Treatment --- History. --- history --- therapy --- Thérapeutique --- Histoire. --- Hépatite C --- Virus de l'hépatite C. --- Histoire du 20ème siècle --- Histoire du 21ème siècle

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Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.

Gastroenterology --- gastro-enterologie --- leverziekten --- hepatitis C --- Hepacivirus --- Hepatitis C, Chronic --- Antiviral Agents --- Liver Transplantation. --- Hepatitis C virus --- Hepatitis C --- Virus de l'hépatite C --- Hépatite C --- pathogenicity. --- therapy. --- therapeutic use. --- Treatment. --- Traitement --- EPUB-LIV-FT LIVMEDEC SPRINGER-B

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Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted.

Hepacivirus. --- Hepatitis C virus. --- Hepatitis C virus --- Viral Vaccines --- Hepatitis, Viral, Human --- Flaviviridae --- Hepatitis Viruses --- Flaviviridae Infections --- Viruses --- Vaccines --- RNA Viruses --- Virus Diseases --- RNA Virus Infections --- Hepatitis --- Vertebrate Viruses --- Diseases --- Organisms --- Biological Products --- Liver Diseases --- Complex Mixtures --- Digestive System Diseases --- Chemicals and Drugs --- Viral Hepatitis Vaccines --- Hepacivirus --- Hepatitis C --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Immunology. --- Medical virology. --- Immunobiology --- HCV (Hepatitis C virus) --- Medicine. --- Drug resistance. --- Virology. --- Hepatology. --- Biomedicine. --- Drug Resistance. --- Life sciences --- Serology --- Gastroenterology --- Microbiology --- Resistance to drugs --- Pharmacology --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Medical microbiology --- Virology --- Virus diseases --- Flaviviruses --- Hepatitis viruses --- Drug interactions. --- Clinical medicine. --- Interactions, Drug --- Drugs --- Medicine, Clinical --- Medicine --- Side effects