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Intoxiqué à l'âge de 21 mois par une bactérie contenue dans un steak haché, devenu lourdement handicapé, Nolan est finalement décédé le 14 septembre 2019. Son calvaire aura duré huit ans. Nolan est mort parce qu'un industriel de la boucherie s'est exonéré de certains contrôles sanitaires avant de livrer ses steaks surgelés à une enseigne de la grande distribution. Nolan est mort faute d'un diagnostic assez rapide, signe scandaleux d'une médecine de classe : d'hôpital en hôpital, personne n'a écouté sa mère, modeste employée alors âgée de 25 ans, alertant en vain sur l'état de son petit garçon. Sans concession ni haine, Priscilla Moittié témoigne aujourd'hui avec son parler vrai. Elle dit la douleur, le sentiment tenace de culpabilité, la colère, mais aussi, et surtout, l'amour et la joie de voir son fils sourire, et même rire, quand tous les médecins le croyaient perdu. Véritable mère-courage, elle raconte son long combat pour obtenir justice, et pour que plus jamais un fabricant de denrées alimentaires n'empoisonne un enfant sans défense.

Foodborne Diseases --- Food Industry --- Disabled Children --- Hemolytic-Uremic Syndrome

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Hemolytic-uremic syndrome. --- Children --- Acute renal failure in children. --- Diseases.

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"This reference presents detailed discussions of the history, pathology, pathophysiology, and approaches to treatment of the complicated, constantly evolving syndromes known as thrombotic thromocytopenic purpura (TTP), from many different points of view. Hemolytic Uremic syndrome and Thrombotic Thrombocytopenic Purpura offers: extensive analyses of the relationship between HUS and TTP; epidemiological studies of HUS from the UK, Canada, Asia, South Africa and Argentina; investigations of non-renal complications of HUS; perspectives on atypical HUS and post-transplantation HUS; delineations of the association between verotoxin and HUS, HUS and pregnancy, and HUS and cancer and cancer tharapy; information on HUS/TTP in HIV-infected patients; explications of the pathology and pathogenesis of HUS; and approaches to treatment of HUS, prognosis, and long-term follow-up.; In addition, it covers the history and pathogenesis of TTP, von Willebrand factor abnormalities in TTP and HUS, platelet agglutinating proteins in TTP, and the treatment of TTP.; With over 2000 literature citations and figures, this book is for nephrologists, hematologists, oncologists, paediatricians, pathologists, gastroenterologists, internists, endocrinologists, infectious disease specialists, neurologists, gynaecologists, microbiologists, surgeons, geneticsts, epidemiologists, radiologists, and medical school students in these disciplines."--Publisher description.

Hemolyse-uremic"syndroom --- Hemolytic-uremic syndrome --- Hemolytique-uremique [Syndrome ] --- Purpura thrombocytopénique thrombotique --- Thrombotic thrombocytopenic purpura --- Trombocytopenische trombotische purpura --- Hemolytic-Uremic Syndrome --- Purpura, Thrombotic Thrombocytopenic --- Child --- Infant --- Infants --- Children --- Minors --- Congenital Thrombotic Thrombocytopenic Purpura --- Familial Thrombotic Thrombocytopenia Purpura --- Familial Thrombotic Thrombocytopenic Purpura --- Microangiopathic Hemolytic Anemia, Congenital --- Moschcowitz Disease --- Schulman-Upshaw Syndrome --- Thrombotic Microangiopathy, Familial --- Thrombotic Thrombocytopenic Purpura --- Upshaw Factor, Deficiency of --- Upshaw-Schulman Syndrome --- Moschkowitz Disease --- Purpura, Thrombotic Thrombopenic --- Thrombotic Thrombocytopenic Purpura, Congenital --- Thrombotic Thrombocytopenic Purpura, Familial --- Disease, Moschcowitz --- Disease, Moschkowitz --- Familial Thrombotic Microangiopathy --- Microangiopathy, Familial Thrombotic --- Schulman Upshaw Syndrome --- Syndrome, Schulman-Upshaw --- Syndrome, Upshaw-Schulman --- Thrombocytopenic Purpura, Thrombotic --- Thrombopenic Purpura, Thrombotic --- Thrombotic Thrombopenic Purpura --- Upshaw Schulman Syndrome --- Disseminated arteriolar-capillary platelet thrombosis --- Febrile pleiochromic anemia --- Microangiopathic hemolytic anemia --- Moschcowitz disease --- Moschcowitz syndrome --- Moschcowitz's disease --- Platelet thrombosis --- Thrombotic microangiopathic hemolytic anemia --- Thrombotic microangiopathy --- Thrombotic thrombocytic anemia --- Thrombotic thrombohemolytic purpura --- TTP (Disease) --- Hemolytic anemia --- Thrombopenic purpura --- Thrombosis --- Gasser syndrome --- Gasser's syndrome --- HUS (Disease) --- Uremic-hemolytic syndrome --- Acute renal failure --- Blood platelet disorders --- Syndromes --- Uremia --- Gasser Syndrome --- Gasser's Syndrome --- Gassers Syndrome --- Hemolytic Uremic Syndrome --- Syndrome, Hemolytic-Uremic --- Hemolytic-uremic syndrome. --- Thrombotic thrombocytopenic purpura. --- In infancy & childhood.

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Advances in immunosuppression and kidney transplant techniques have led to significant improvements in the short-term survival of the renal allograft. Long-term graft survival, however, has relatively lagged behind and has now become one of the main problems in kidney transplantation. In this Special Issue, we discuss the recent research developments in kidney transplants that may affect long-term allografts, as well as the survival of the patient. The latest developments in living kidney donation are also explored.

Medicine --- malondialdehyde --- oxidative stress --- new-onset diabetes --- renal transplantation --- BK virus --- BK virus nephropathy --- kidney allograft --- transplantation --- Alport syndrome --- children --- autosomal dominant polycystic kidney disease --- epidemiology --- hospitalization --- kidney transplantation --- subarachnoid hemorrhage --- malignancy --- post-transplant malignancy --- renal cell carcinoma --- meta-analysis --- systematic reviews --- tacrolimus --- C/D-ratio --- pharmacokinetics --- opportunistic infection --- allograft survival --- urological complications --- ureteric stent --- urinary tract infection --- timing of removal --- living donor --- ethnicity --- age --- obesity --- genetic relationship donor/recipient --- atypical hemolytic uremic syndrome --- eculizumab --- glucose intolerance --- insulin secretion --- insulin resistance --- oral glucose tolerance test --- healthy subject --- hyperchloremia --- kidney graft dysfunction --- living donor kidney transplantation --- Uropathogenic E. coli --- UPEC --- phylogeny --- genomics --- antibiotic resistance --- virulence traits --- night-time renal transplantation --- graft survival --- patient survival/outcome --- surgical complications --- acute rejection --- lymphocyte --- CD45RC --- Belatacept --- cardiovascular high risk --- outcome --- machine perfusion --- organ preservation --- temperature --- hypothermic --- normothermic --- transplant --- proton-pump inhibitors --- iron --- iron deficiency --- polyomavirus --- BKV --- kidney --- glomerulus --- BKVAN --- nephropathy --- fluid management --- delayed graft function --- goal-directed fluid therapy --- calcineurin inhibitor nephrotoxcity --- C/D ratio --- tacrolimus metabolism --- ADPKD --- native nephrectomy --- patient outcome --- perioperative complications --- epidermal growth factor --- creatinine --- graft failure --- renal transplantation. --- new onset diabetes after renal transplantation --- single nucleotide polymorphisms --- n/a --- urinary biomarkers --- α-GST --- π-GST --- nephrotoxicity --- urinary excretion of N1-methylnicotinamide --- mortality --- niacin status --- dietary intake --- tryptophan --- vitamin B3 --- Kidney transplant --- vitamin C --- cancer mortality --- oxidative stress. --- mycophenolic acid --- immunosuppression --- plasmapheresis --- oxalate --- hyperoxaluria --- kidney transplant recipients --- post-transplantation diabetes mellitus --- all-cause mortality --- cardiovascular mortality --- infectious mortality --- magnesium --- hypomagnesaemia --- cancer --- kidney transplant --- survival --- living kidney donation --- living-donor kidney transplantation --- beliefs --- inequity --- ischemia reperfusion injury --- innate immune system --- adaptive immune system --- apoptosis --- necrosis --- hypoxic inducible factor --- endothelial dysfunction --- proton pump inhibitor --- transplant rejection --- GFR --- insulin-like growth factor 1 --- growth hormone --- muscle mass --- patient survival --- physical activity --- renal transplant recipients --- kidney transplant (KT) --- donor-specific antibodies (DSA) --- C3d-binding assay --- antibody-mediated rejection (AMR) --- arsenic --- diet --- fish consumption --- post-transplant diabetes mellitus --- N1-methyl-2-pyridone-5-carboxamide --- N1-methylnicotinamide --- urinary excretion --- kidney function --- biomarker --- branched chain amino acids --- posttransplant diarrhea --- methanogenesis --- Methanosphaera stadtmanae --- mucins --- sulfate-reducing bacteria --- acute humoral rejection --- first-line therapy --- outcomes --- proteasome inhibitor --- renal transplant --- transplant recipients --- calcineurin inhibitors --- FK506 --- pharmacokinetic --- fast tacrolimus metabolizers

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Advances in immunosuppression and kidney transplant techniques have led to significant improvements in the short-term survival of the renal allograft. Long-term graft survival, however, has relatively lagged behind and has now become one of the main problems in kidney transplantation. In this Special Issue, we discuss the recent research developments in kidney transplants that may affect long-term allografts, as well as the survival of the patient. The latest developments in living kidney donation are also explored.

malondialdehyde --- oxidative stress --- new-onset diabetes --- renal transplantation --- BK virus --- BK virus nephropathy --- kidney allograft --- transplantation --- Alport syndrome --- children --- autosomal dominant polycystic kidney disease --- epidemiology --- hospitalization --- kidney transplantation --- subarachnoid hemorrhage --- malignancy --- post-transplant malignancy --- renal cell carcinoma --- meta-analysis --- systematic reviews --- tacrolimus --- C/D-ratio --- pharmacokinetics --- opportunistic infection --- allograft survival --- urological complications --- ureteric stent --- urinary tract infection --- timing of removal --- living donor --- ethnicity --- age --- obesity --- genetic relationship donor/recipient --- atypical hemolytic uremic syndrome --- eculizumab --- glucose intolerance --- insulin secretion --- insulin resistance --- oral glucose tolerance test --- healthy subject --- hyperchloremia --- kidney graft dysfunction --- living donor kidney transplantation --- Uropathogenic E. coli --- UPEC --- phylogeny --- genomics --- antibiotic resistance --- virulence traits --- night-time renal transplantation --- graft survival --- patient survival/outcome --- surgical complications --- acute rejection --- lymphocyte --- CD45RC --- Belatacept --- cardiovascular high risk --- outcome --- machine perfusion --- organ preservation --- temperature --- hypothermic --- normothermic --- transplant --- proton-pump inhibitors --- iron --- iron deficiency --- polyomavirus --- BKV --- kidney --- glomerulus --- BKVAN --- nephropathy --- fluid management --- delayed graft function --- goal-directed fluid therapy --- calcineurin inhibitor nephrotoxcity --- C/D ratio --- tacrolimus metabolism --- ADPKD --- native nephrectomy --- patient outcome --- perioperative complications --- epidermal growth factor --- creatinine --- graft failure --- renal transplantation. --- new onset diabetes after renal transplantation --- single nucleotide polymorphisms --- n/a --- urinary biomarkers --- α-GST --- π-GST --- nephrotoxicity --- urinary excretion of N1-methylnicotinamide --- mortality --- niacin status --- dietary intake --- tryptophan --- vitamin B3 --- Kidney transplant --- vitamin C --- cancer mortality --- oxidative stress. --- mycophenolic acid --- immunosuppression --- plasmapheresis --- oxalate --- hyperoxaluria --- kidney transplant recipients --- post-transplantation diabetes mellitus --- all-cause mortality --- cardiovascular mortality --- infectious mortality --- magnesium --- hypomagnesaemia --- cancer --- kidney transplant --- survival --- living kidney donation --- living-donor kidney transplantation --- beliefs --- inequity --- ischemia reperfusion injury --- innate immune system --- adaptive immune system --- apoptosis --- necrosis --- hypoxic inducible factor --- endothelial dysfunction --- proton pump inhibitor --- transplant rejection --- GFR --- insulin-like growth factor 1 --- growth hormone --- muscle mass --- patient survival --- physical activity --- renal transplant recipients --- kidney transplant (KT) --- donor-specific antibodies (DSA) --- C3d-binding assay --- antibody-mediated rejection (AMR) --- arsenic --- diet --- fish consumption --- post-transplant diabetes mellitus --- N1-methyl-2-pyridone-5-carboxamide --- N1-methylnicotinamide --- urinary excretion --- kidney function --- biomarker --- branched chain amino acids --- posttransplant diarrhea --- methanogenesis --- Methanosphaera stadtmanae --- mucins --- sulfate-reducing bacteria --- acute humoral rejection --- first-line therapy --- outcomes --- proteasome inhibitor --- renal transplant --- transplant recipients --- calcineurin inhibitors --- FK506 --- pharmacokinetic --- fast tacrolimus metabolizers