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The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origi

Heart -- Diseases -- Treatment. --- Heart -- growth & development. --- Heart -- Growth. --- Heart -- physiology. --- Myocardium -- Regeneration. --- Regeneration. --- Regenerative Medicine -- methods. --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiology --- Heart --- Anatomy --- Anatomies --- Hearts

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Biomedical, pharmaceutical and medical personnel are interested in studying aspects of arrhythmias at a basic, translational and applied level. The overall understanding of the molecular basis of disease has dramatically increased, as well as the number of available and emerging molecular, pharmacological and device treatment based therapies. Cardiac Electrophysiology Methods and Models will review key research methods and protocols in cardiac electrophysiology with a focus on advantages, pitfalls, practical implementation and collaborative cross-functional research.

Electrocardiography. --- Electrotherapeutics. --- Heart -- Diseases -- Treatment. --- Heart -- Electric properties. --- Heart --- Electrocardiography --- Electrotherapeutics --- Models, Biological --- Heart Function Tests --- Electrodiagnosis --- Electrophysiologic Techniques, Cardiac --- Models, Cardiovascular --- Diagnostic Techniques and Procedures --- Models, Theoretical --- Diagnostic Techniques, Cardiovascular --- Diagnosis --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Human Anatomy & Physiology --- Medicine --- Cardiovascular Diseases --- Physiology --- Health & Biological Sciences --- Electric properties --- Diseases --- Treatment --- Electric properties. --- Treatment. --- Electrotherapy --- Faradization --- ECG --- EKG --- Electrocardiograms --- Medicine. --- Cardiology. --- Medicine & Public Health. --- Electricity in medicine --- Electrostatics --- Physical therapy --- Therapeutics, Physiological --- Neural stimulation --- Internal medicine

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This book collects several contributions, written both by statisticians and medical doctors, which focus on the identification of new diagnostic, therapeutic and organizational strategies in order to improve the occurrence of clinical outcomes for Acute Coronary Syndromes (ACS) patients. The work is structured in two different parts: the first one is focused on cooperative project mainly on statistical analysis of large clinical and administrative databases; the second one faces the development of innovative diagnostic techniques, with specific reference to genetic and proteomic, and the evolution of new imaging techniques for the early identification of patients at major risk of thrombotic, arrhythmic complications and at risk of poor revascularization.

Cardiology. --- Heart -- Diseases -- Diagnosis. --- Heart -- Diseases -- Statistics. --- Heart -- Diseases -- Treatment. --- Practice of medicine. --- Coronary heart disease --- Risk --- Data Collection --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Myocardial Ischemia --- Epidemiologic Methods --- Heart Diseases --- Probability --- Cardiovascular Diseases --- Statistics as Topic --- Investigative Techniques --- Diseases --- Diagnosis --- Acute Coronary Syndrome --- Risk Factors --- Registries --- Mathematics --- Physical Sciences & Mathematics --- Mathematical Statistics --- Heart --- Diagnosis. --- Treatment. --- Statistics. --- Health administration. --- Health economics. --- Medical economics. --- Statistics for Life Sciences, Medicine, Health Sciences. --- Health Economics. --- Health Administration. --- Medical practice --- Practice of medicine --- Physician practice acquisitions --- Economics, Medical --- Health --- Health economics --- Hygiene --- Medical care --- Medicine --- Internal medicine --- Statistical analysis --- Statistical data --- Statistical methods --- Statistical science --- Econometrics --- Economic aspects --- Statistics .

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With the medical device industry growing at an incredible pace, and the overall understanding of the molecular basis for disease on the rise, today’s bio-medical engineers face a constant challenge to re-tool or reinvent devices that remain in step with medical science. In Handbook of Cardiac Anatomy, Physiology, and Devices, Second Edition, leading experts from the University of Minnesota’s renowned Lillehei Heart Institute and scientists from Medtronic, Inc. have thoroughly updated and expanded upon the critically acclaimed first edition with the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease, and genomics-based tools and technology. Once again, a companion compact disk offers unique insights into the working heart, providing color images and movies that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology, and Devices, Second Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices. .

Heart -- Anatomy -- Handbooks, manuals, etc. --- Heart -- Diseases -- Treatment -- Handbooks, manuals, etc. --- Heart -- Physiology -- Handbooks, manuals, etc. --- Heart --- Heart, Artificial --- Cardiovascular System --- Assisted Circulation --- Cardiovascular Diseases --- Prostheses and Implants --- Artificial Organs --- Diseases --- Surgical Procedures, Operative --- Anatomy --- Heart-Assist Devices --- Heart Diseases --- Surgical Equipment --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Equipment and Supplies --- Medicine --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiology --- Treatment --- Medicine. --- Angiology. --- Cardiology. --- Pathology. --- Cardiac surgery. --- Biomedical engineering. --- Medicine & Public Health. --- Biomedical Engineering. --- Cardiac Surgery. --- Cardiopulmonary system --- Cardiovascular system --- Chest --- Angiography. --- Biomedical Engineering and Bioengineering. --- Surgery. --- Cardiac surgery --- Open-heart surgery --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Blood-vessels --- Diagnosis, Radioscopic --- Radiography, Medical --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Internal medicine --- Surgery --- Radiography

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Angiogenesis and lymphangiogenesis have become attractive targets for drug therapy because of their key roles in a broad spectrum of pathological disease states ranging from macular degeneration to tumor growth and metastasis. A substantial increase in the research effort over the past decade has deepened our understanding of the basic mechanisms underlying angiogenesis and lymphangiogenesis, promoting the development of promising therapeutics for the clinical management of vascular-related diseases. These extraordinary advancements have been built upon a vast array of diverse analytical techniques developed globally throughout the field. Over the years, these methods have evolved to suit the specific needs of different researchers and experimental scenarios, resulting in a myriad of technical variants of basic assay approaches.  "The Textbook of Angiogenesis and Lymphangiogenesis: Methods and Applications" is an up-to-date comprehensive textbook on angiogenesis and lymphangiogenesis techniques and applications. This volume is designed to embody the collective works of experts in the clinical as well as the basic research arenas who have significantly contributed to the development and application of techniques in all areas of angiogenesis and lymphangiogenesis. Each chapter introduces and discusses one or a group of closely related techniques and convey step-by-step protocol information and detailed technical guidance to the reader. Emphasis has been placed on explanatory illustrations, critical technical steps as well as divulging information on the benefits and caveats of specific practices related to the methods discussed. This manual is intended to serve as a written guide for both newcomers and established professionals in the field.

Angiogenesis. --- Heart -- Diseases -- Treatment. --- Medicine. --- Neovascularization --- Publication Formats --- Epithelial Cells --- Animal Diseases --- Organogenesis --- Models, Animal --- Angiogenic Proteins --- Models, Biological --- Cardiovascular Physiological Processes --- Intercellular Signaling Peptides and Proteins --- Embryonic and Fetal Development --- Investigative Techniques --- Diseases --- Publication Characteristics --- Cells --- Models, Theoretical --- Cardiovascular Physiological Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Anatomy --- Peptides --- Biological Factors --- Circulatory and Respiratory Physiological Phenomena --- Proteins --- Morphogenesis --- Amino Acids, Peptides, and Proteins --- Growth and Development --- Phenomena and Processes --- Chemicals and Drugs --- Physiological Processes --- Physiological Phenomena --- Endothelial Cells --- Vascular Endothelial Growth Factors --- Laboratory Manuals --- Disease Models, Animal --- Lymphangiogenesis --- Neovascularization, Physiologic --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiology --- Angiogenesis, Physiological --- Neovascularization, Physiological --- Physiologic Angiogenesis --- Physiologic Neovascularization --- Angiogenesis, Physiologic --- Physiological Angiogenesis --- Physiological Neovascularization --- Lymphangiogeneses --- Lymphatic Vessels --- Animal Disease Model --- Animal Disease Models --- Disease Model, Animal --- VEGFs --- Capillary Endothelial Cells --- Lymphatic Endothelial Cells --- Vascular Endothelial Cells --- Capillary Endothelial Cell --- Cell, Capillary Endothelial --- Cell, Endothelial --- Cell, Lymphatic Endothelial --- Cell, Vascular Endothelial --- Cells, Capillary Endothelial --- Cells, Endothelial --- Cells, Lymphatic Endothelial --- Cells, Vascular Endothelial --- Endothelial Cell --- Endothelial Cell, Capillary --- Endothelial Cell, Lymphatic --- Endothelial Cell, Vascular --- Endothelial Cells, Capillary --- Endothelial Cells, Lymphatic --- Endothelial Cells, Vascular --- Lymphatic Endothelial Cell --- Vascular Endothelial Cell --- Physiological Concepts --- Physiological Phenomenon --- Physiological Process --- Concept, Physiological --- Concepts, Physiological --- Phenomena, Physiological --- Phenomenas, Physiological --- Phenomenon, Physiological --- Physiological Concept --- Process, Physiological --- Processes, Physiological --- Development and Growth --- Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- Circulatory and Respiratory Physiological Phenomenon --- Physiology, Circulatory and Respiratory --- Circulatory and Respiratory Physiology --- Biologic Agents --- Biologic Factors --- Biological Factor --- Factor, Biologic --- Factor, Biological --- Factors, Biological --- Biological Agents --- Agents, Biologic --- Agents, Biological --- Biologic Factor --- Factors, Biologic --- Polypeptides --- Anatomies --- Cardiovascular Physiological Concepts --- Cardiovascular Physiological Phenomenon --- Cardiovascular Physiological Process --- Physiology, Cardiovascular --- Cardiovascular Physiologic Processes --- Cardiovascular Physiology --- Cardiovascular Physiological Concept --- Cardiovascular Physiological Phenomenas --- Concept, Cardiovascular Physiological --- Concepts, Cardiovascular Physiological --- Phenomena, Cardiovascular Physiological --- Phenomenon, Cardiovascular Physiological --- Physiologic Processes, Cardiovascular --- Physiological Concept, Cardiovascular --- Physiological Concepts, Cardiovascular --- Physiological Phenomena, Cardiovascular --- Physiological Phenomenon, Cardiovascular --- Physiological Process, Cardiovascular --- Physiological Processes, Cardiovascular --- Process, Cardiovascular Physiological --- Processes, Cardiovascular Physiologic --- Processes, Cardiovascular Physiological --- Cardiovascular System --- Experimental Model --- Experimental Models --- Mathematical Model --- Model, Experimental --- Models (Theoretical) --- Models, Experimental --- Models, Theoretic --- Theoretical Study --- Mathematical Models --- Model (Theoretical) --- Model, Mathematical --- Model, Theoretical --- Models, Mathematical --- Studies, Theoretical --- Study, Theoretical --- Theoretical Model --- Theoretical Models --- Theoretical Studies --- Cell --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Prenatal Programming --- Embryo and Fetal Development --- Programming, Prenatal --- Growth Factors --- Paracrine Peptide Factors --- Paracrine Protein Factors --- Peptide Factors, Paracrine --- Biological Model --- Biological Models --- Model, Biological --- Models, Biologic --- Biologic Model --- Biologic Models --- Model, Biologic --- Experimental Animal Models --- Laboratory Animal Models --- Animal Model --- Animal Model, Experimental --- Animal Model, Laboratory --- Animal Models --- Animal Models, Experimental --- Animal Models, Laboratory --- Experimental Animal Model --- Laboratory Animal Model --- Model, Animal --- Model, Experimental Animal --- Model, Laboratory Animal --- Models, Experimental Animal --- Models, Laboratory Animal --- Diseases, Animal --- Disease --- Adenomatous Epithelial Cells --- Columnar Glandular Epithelial Cells --- Cuboidal Glandular Epithelial Cells --- Glandular Epithelial Cells --- Squamous Cells --- Squamous Epithelial Cells --- Transitional Epithelial Cells --- Adenomatous Epithelial Cell --- Cell, Adenomatous Epithelial --- Cell, Epithelial --- Cell, Glandular Epithelial --- Cell, Squamous --- Cell, Squamous Epithelial --- Cell, Transitional Epithelial --- Cells, Adenomatous Epithelial --- Cells, Epithelial --- Cells, Glandular Epithelial --- Cells, Squamous --- Cells, Squamous Epithelial --- Cells, Transitional Epithelial --- Epithelial Cell --- Epithelial Cell, Adenomatous --- Epithelial Cell, Glandular --- Epithelial Cell, Squamous --- Epithelial Cell, Transitional --- Epithelial Cells, Adenomatous --- Epithelial Cells, Glandular --- Epithelial Cells, Squamous --- Epithelial Cells, Transitional --- Glandular Epithelial Cell --- Squamous Cell --- Squamous Epithelial Cell --- Transitional Epithelial Cell --- Epithelium --- Angiogenesis --- growth & development --- physiology --- veterinary --- cytology --- Angiogenic Peptides --- Cancer research. --- Angiology. --- Cell culture. --- Biomedicine. --- Biomedicine general. --- Cancer Research. --- Cell Culture. --- Oncology. --- Angiography. --- Blood-vessels --- Diagnosis, Radioscopic --- Radiography, Medical --- Tumors --- Cultures (Biology) --- Cytology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Radiography --- Technique --- Health Workforce --- Neovascularization. --- Biomedicine, general. --- Cancer research