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Dans les discours politiques, la science est aujourd'hui de plus en plus convoquée pour énoncer des vérités incontestables. Pourtant, suite à de nombreux scandales sanitaires, un climat de suspicion s'est installé, creusant un fossé entre les chercheurs et les citoyens. Chacun est alors confronté à ces questions essentielles s'agissant de la santé : qui croire ? Que nous cache-t-on ? À qui profite la science ? Ces questions sont au cœur de ce livre, qui analyse comment de nombreux chercheurs ont participé à un processus de confiscation de la science au service des intérêts privés de grands groupes industriels, souvent avec la complicité active de l'État. Ils ont ainsi contribué à instaurer l'hégémonie d'une « stratégie du doute » quant aux risques industriels (amiante, plomb, nucléaire, pesticides, etc.) et à leurs conséquences. S'appuyant sur sa propre expérience professionnelle et sur celle d'Henri Pézerat, toxicologue connu pour son engagement scientifique et citoyen contre l'amiante, Annie Thébaud-Mony dénonce ici avec force le cynisme et l'impunité de ceux qui, délibérément, ont choisi la mort des autres pour leur plus grand profit. Ses révélations dressent un réquisitoire implacable, qui invite à résister à l'imposture scientifique et à mettre en synergie, en matière de santé publique, savoirs scientifiques et savoirs citoyens.

Health risk assessment.

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This book combines new research data with findings from present-day health surveys to examine the history of ill health and its outcomes, whether recovery or death, in Europe and North America from the 17th century to the present. Some forecasts about future sickness rates and trends are included.

Health risk assessment.

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• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Health risk assessment

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Health risk assessment

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

As part of its core mission, the U.S. Environmental Protection Agency (EPA) is tasked with assessing the hazards and risks to human health from exposure to pollutants. While some pollutants are well studied, there are little or no data on the potential health effects for many thousands of chemicals that can make their way into the environment, such as PFAS. EPA still relies on laboratory mammalian studies as the foundation of most human health risk assessments, which are limited by high costs, long timelines, and other concerns. New approach methods (NAMs) in toxicology, for example new in vivo and in vitro strategies and computational systems biology, offer opportunities to inform timely decision-making when no data are available from laboratory mammalian toxicity tests or epidemiological studies. NAMs may also help inform efforts to protect susceptible and vulnerable populations by characterizing subtle health perturbations, better encompassing genetic diversity, and accounting for nonchemical stressors. While the promise and need for NAMs is clear, many barriers to their use remain. This report aims to bridge the gap between the potential of NAMs and their practical application in human health risk assessment. Building Confidence in New Evidence Streams for Human Health Risk Assessment draws lessons learned from laboratory mammalian toxicity tests to help inform approaches for building scientific confidence in NAMs and for incorporating such data into risk assessment and decision-making. Overall, the report recommendations aim to ensure a seamless handoff from the evaluation of NAM-based testing strategies in the laboratory to the incorporation of NAM data into modern, systematic-review-based risk assessments.

Health risk assessment