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En 1920, en Virginie, naît une petite fille afro-américaine dont les cellules vont révolutionner l'histoire de la médecine sans que les manuels de biologie ne mentionnent sa véritable identité. A partir d'un prélèvement dont elle n'avait pas été informée, la plupart des laboratoires du monde entier vont travailler sur la lignée de ses cellules cancéreuses, les premières à pouvoir être cultivées indéfiniment in vitro. Cent ans plus tard, une journaliste se met en quête de sa trace, télescopant passé et présent, ségrégation raciale et désir de liberté... Qui donc était Henrietta Lacks ?

HeLa Cells. --- Cellules HeLa --- histoire. --- Lacks, Henrietta,

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Une adolescente découvre l'histoire d'Henrietta Lacks, jeune mère de famille afro-américaine, dans un ancien numéro du magazine Rolling Stone. Atteinte d'un cancer du col l'utérus, ses cellules ont été prélevées et utilisées sans son consentement. Les cellules HeLa, qui ont révolutionné la médecine moderne et permis le développement de plusieurs vaccins, se retrouvent désormais dans de nombreux laboratoires de recherche !

HeLa Cells. --- Ethics, Medical. --- Women in science. --- Cellules HeLa --- histoire. --- Lacks, Henrietta, --- Lacks, Henrietta,

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Cancer --- African American women --- Human experimentation in medicine --- HeLa cells --- Cancer --- Cell culture --- Medical ethics --- Lacks, Henrietta, - 1920-1951

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Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer, yet her cells--taken without her knowledge--became one of the most important tools in medicine. The first "immortal" human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer and viruses; helped lead to in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks is buried in an unmarked grave. Her family did not learn of her "immortality" until more than twenty years after her death, when scientists began using her husband and children in research without informed consent. The story of the Lacks family is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of--From publisher description.

Cultures cellulaires. --- Noirs américains. --- Secret médical. --- Responsabilité civile. --- Expérimentation humaine en médecine --- Éthique médicale. --- Cancer --- African American women --- Human experimentation in medicine --- HeLa cells. --- Cell culture. --- Medical ethics. --- Histoire. --- Recherche. --- Patients --- History. --- Research. --- Lacks, Henrietta, --- Health. --- Professional ethics. Deontology --- Human rights --- Medical law --- History of human medicine --- Human genetics --- Tissue donors --- Tissue and organ procurement --- African Americans --- Confidentiality --- Prejudice --- HeLa cells --- Human experimentation --- ethics --- Noirs américains. --- Secret médical. --- Responsabilité civile. --- Expérimentation humaine en médecine --- Éthique médicale.

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The Special issue "Biological and Pharmacological Activity of Plant Natural Compounds II" is continuing the intriguing research on the use of natural plant products. The second edition follows the aim of the first one.

Medicine --- Pharmacology --- Bergenia species --- botanical description --- traditional uses --- phytochemistry --- pharmacology --- anti-urolithiatic activity --- bergenin --- Flaxseed oil --- linusorb B3 --- anti-cancer --- apoptosis --- actin polymerization --- Src --- glioblastoma --- chlorogenic acid --- coffee --- cyclooxygenase --- espresso --- instant coffee --- platelet aggregation --- Rubia tinctorum L. --- antioxidants --- polyphenols --- ethylene glycol --- urolithiasis --- histophatology --- Saccharomyces cerevisiae --- β-glucan --- antimicrobial and anticancer activities --- detoxification ability --- immunomodulatory effect --- Aquilaria sinensis --- pheophorbide A --- MMP-2 --- MMP-9 --- HT-1080 --- advanced glycation end product (AGE) --- oxidative stress --- epithelial to mesenchymal transition --- AGE-inhibitor --- swertiamarin --- diabetic nephropathy --- astragaloside IV --- Astragalus membranaceus --- huang qi --- Astragali Radix --- liver --- liver regeneration --- 70% partial hepatectomy --- proliferation --- rat --- memory --- object recognition --- Ginkgo biloba --- dorsal hippocampus formation --- brain-derived neurotrophic factor --- Diclofenac --- γ-lactone --- nano-emulsion --- methylcellulose --- Ostrich oil --- Struthio camelus --- Caenorhabditis elegans --- leaf extract --- neuroprotection --- antioxidant activity --- DAF-16 --- Clerodendrum infortunatum --- terpenoids --- phenylpropanoids --- antidiabetic --- breast cancer --- Combretum indicum L. --- antidiabetic activity --- histopathology --- UPLC-QTOF/ESI-MS --- network pharmacology --- Biebersteinia heterostemon --- galegine --- hypotensive --- toxicity --- Sage --- Salvia officinalis --- cytotoxicity --- hepatoprotection --- MDA --- TAOxC --- MCF-7 --- HeLA cells --- HepG-2 cells --- Peganum harmala --- anti-inflammatory activity --- antioxidant --- LC-ESI-MS/MS --- traditional medicine --- rheumatoid arthritis --- rosmanol --- carnosol --- Callicarpa longissima --- TLR4/NF-κB/MAPK --- synergistic effect --- diabetes mellitus --- anti-diabetic drugs --- monoterpenes --- Bergenia species --- botanical description --- traditional uses --- phytochemistry --- pharmacology --- anti-urolithiatic activity --- bergenin --- Flaxseed oil --- linusorb B3 --- anti-cancer --- apoptosis --- actin polymerization --- Src --- glioblastoma --- chlorogenic acid --- coffee --- cyclooxygenase --- espresso --- instant coffee --- platelet aggregation --- Rubia tinctorum L. --- antioxidants --- polyphenols --- ethylene glycol --- urolithiasis --- histophatology --- Saccharomyces cerevisiae --- β-glucan --- antimicrobial and anticancer activities --- detoxification ability --- immunomodulatory effect --- Aquilaria sinensis --- pheophorbide A --- MMP-2 --- MMP-9 --- HT-1080 --- advanced glycation end product (AGE) --- oxidative stress --- epithelial to mesenchymal transition --- AGE-inhibitor --- swertiamarin --- diabetic nephropathy --- astragaloside IV --- Astragalus membranaceus --- huang qi --- Astragali Radix --- liver --- liver regeneration --- 70% partial hepatectomy --- proliferation --- rat --- memory --- object recognition --- Ginkgo biloba --- dorsal hippocampus formation --- brain-derived neurotrophic factor --- Diclofenac --- γ-lactone --- nano-emulsion --- methylcellulose --- Ostrich oil --- Struthio camelus --- Caenorhabditis elegans --- leaf extract --- neuroprotection --- antioxidant activity --- DAF-16 --- Clerodendrum infortunatum --- terpenoids --- phenylpropanoids --- antidiabetic --- breast cancer --- Combretum indicum L. --- antidiabetic activity --- histopathology --- UPLC-QTOF/ESI-MS --- network pharmacology --- Biebersteinia heterostemon --- galegine --- hypotensive --- toxicity --- Sage --- Salvia officinalis --- cytotoxicity --- hepatoprotection --- MDA --- TAOxC --- MCF-7 --- HeLA cells --- HepG-2 cells --- Peganum harmala --- anti-inflammatory activity --- antioxidant --- LC-ESI-MS/MS --- traditional medicine --- rheumatoid arthritis --- rosmanol --- carnosol --- Callicarpa longissima --- TLR4/NF-κB/MAPK --- synergistic effect --- diabetes mellitus --- anti-diabetic drugs --- monoterpenes