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Book
Modern Strategies for Heterocycle Synthesis
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Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.

Keywords

Medicine --- amine nucleophiles --- alkynoic acids --- cascade reaction --- gold catalysis --- fused N-heterocycles --- solid-phase synthesis --- ketone --- traceless synthesis --- natural products --- enol ethers --- photocatalysis --- photoredox --- visible-light-induced catalysis --- photoredox cyclization --- organic dyes --- heterocycles --- dihydrocoumarins --- synthesis --- 3-trifluoroacetyl coumarins --- phenols --- antifungal activities --- terpyridines --- 3,2':6',3"-terpyridine --- cyclohexanol derivative --- condensation --- heterocyclic --- 1,2,3-triazol --- triazolylmethyl phosphinate --- triazolylmethyl phosphate --- copper-catalyzed azide-alkyne cycloaddition --- click reaction --- azides --- cinnolines --- triazoles --- CuAAC --- alkynes --- cycloalkynes --- Richter cyclization --- Suzuki coupling --- fluorescence --- cytotoxicity --- coumarin --- pyrazolo[3,4-b]pyridine --- silica sulfuric acid --- 2H-pyran --- valence isomerism --- 1-oxa-triene --- dienone --- oxa-electrocyclization --- Knoevenagel --- propargyl Claisen --- cycloisomerization --- asymmetric dimeric β-carboline --- acylhydrazone group --- cytotoxic --- antitumor --- structure-activity relationship --- γ-lactam --- pyrrolidones --- multicomponent reactions --- organocatalysis --- pyridine --- CF3CO-acetylenes --- 1,3-oxazines --- fluorinated heterocycles --- saturated oxygen heterocycles --- cyclic ethers --- total synthesis --- multicomponent reaction --- α-halohydrazones --- Staudinger reaction --- aza-Wittig --- 1H-imidazole-2(3H)-thione --- 2H-imidazo[2,1-b][1,3,4]thiadiazine --- purine --- nucleobase --- aromatic substitution --- arylation --- fluoroalcohol --- α-chloroglycinates --- 5-acylamino-1,3-thiazoles --- Hantzsch reaction --- TMSBr --- propargylic alcohols --- cascade cyclization --- 4-bromo quinolines --- synthesis of benzofurans --- intra-molecular approach --- inter-molecular approach --- amine nucleophiles --- alkynoic acids --- cascade reaction --- gold catalysis --- fused N-heterocycles --- solid-phase synthesis --- ketone --- traceless synthesis --- natural products --- enol ethers --- photocatalysis --- photoredox --- visible-light-induced catalysis --- photoredox cyclization --- organic dyes --- heterocycles --- dihydrocoumarins --- synthesis --- 3-trifluoroacetyl coumarins --- phenols --- antifungal activities --- terpyridines --- 3,2':6',3"-terpyridine --- cyclohexanol derivative --- condensation --- heterocyclic --- 1,2,3-triazol --- triazolylmethyl phosphinate --- triazolylmethyl phosphate --- copper-catalyzed azide-alkyne cycloaddition --- click reaction --- azides --- cinnolines --- triazoles --- CuAAC --- alkynes --- cycloalkynes --- Richter cyclization --- Suzuki coupling --- fluorescence --- cytotoxicity --- coumarin --- pyrazolo[3,4-b]pyridine --- silica sulfuric acid --- 2H-pyran --- valence isomerism --- 1-oxa-triene --- dienone --- oxa-electrocyclization --- Knoevenagel --- propargyl Claisen --- cycloisomerization --- asymmetric dimeric β-carboline --- acylhydrazone group --- cytotoxic --- antitumor --- structure-activity relationship --- γ-lactam --- pyrrolidones --- multicomponent reactions --- organocatalysis --- pyridine --- CF3CO-acetylenes --- 1,3-oxazines --- fluorinated heterocycles --- saturated oxygen heterocycles --- cyclic ethers --- total synthesis --- multicomponent reaction --- α-halohydrazones --- Staudinger reaction --- aza-Wittig --- 1H-imidazole-2(3H)-thione --- 2H-imidazo[2,1-b][1,3,4]thiadiazine --- purine --- nucleobase --- aromatic substitution --- arylation --- fluoroalcohol --- α-chloroglycinates --- 5-acylamino-1,3-thiazoles --- Hantzsch reaction --- TMSBr --- propargylic alcohols --- cascade cyclization --- 4-bromo quinolines --- synthesis of benzofurans --- intra-molecular approach --- inter-molecular approach


Book
Modern Strategies for Heterocycle Synthesis
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.

Keywords

Medicine --- amine nucleophiles --- alkynoic acids --- cascade reaction --- gold catalysis --- fused N-heterocycles --- solid-phase synthesis --- ketone --- traceless synthesis --- natural products --- enol ethers --- photocatalysis --- photoredox --- visible-light-induced catalysis --- photoredox cyclization --- organic dyes --- heterocycles --- dihydrocoumarins --- synthesis --- 3-trifluoroacetyl coumarins --- phenols --- antifungal activities --- terpyridines --- 3,2′:6′,3″-terpyridine --- cyclohexanol derivative --- condensation --- heterocyclic --- 1,2,3-triazol --- triazolylmethyl phosphinate --- triazolylmethyl phosphate --- copper-catalyzed azide-alkyne cycloaddition --- click reaction --- azides --- cinnolines --- triazoles --- CuAAC --- alkynes --- cycloalkynes --- Richter cyclization --- Suzuki coupling --- fluorescence --- cytotoxicity --- coumarin --- pyrazolo[3,4-b]pyridine --- silica sulfuric acid --- 2H-pyran --- valence isomerism --- 1-oxa-triene --- dienone --- oxa-electrocyclization --- Knoevenagel --- propargyl Claisen --- cycloisomerization --- asymmetric dimeric β-carboline --- acylhydrazone group --- cytotoxic --- antitumor --- structure–activity relationship --- γ-lactam --- pyrrolidones --- multicomponent reactions --- organocatalysis --- pyridine --- CF3CO-acetylenes --- 1,3-oxazines --- fluorinated heterocycles --- saturated oxygen heterocycles --- cyclic ethers --- total synthesis --- multicomponent reaction --- α-halohydrazones --- Staudinger reaction --- aza-Wittig --- 1H-imidazole-2(3H)-thione --- 2H-imidazo[2,1-b][1,3,4]thiadiazine --- purine --- nucleobase --- aromatic substitution --- arylation --- fluoroalcohol --- α-chloroglycinates --- 5-acylamino-1,3-thiazoles --- Hantzsch reaction --- TMSBr --- propargylic alcohols --- cascade cyclization --- 4-bromo quinolines --- synthesis of benzofurans --- intra-molecular approach --- inter-molecular approach --- n/a --- 3,2':6',3"-terpyridine --- structure-activity relationship


Book
Modern Strategies for Heterocycle Synthesis
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.

Keywords

amine nucleophiles --- alkynoic acids --- cascade reaction --- gold catalysis --- fused N-heterocycles --- solid-phase synthesis --- ketone --- traceless synthesis --- natural products --- enol ethers --- photocatalysis --- photoredox --- visible-light-induced catalysis --- photoredox cyclization --- organic dyes --- heterocycles --- dihydrocoumarins --- synthesis --- 3-trifluoroacetyl coumarins --- phenols --- antifungal activities --- terpyridines --- 3,2′:6′,3″-terpyridine --- cyclohexanol derivative --- condensation --- heterocyclic --- 1,2,3-triazol --- triazolylmethyl phosphinate --- triazolylmethyl phosphate --- copper-catalyzed azide-alkyne cycloaddition --- click reaction --- azides --- cinnolines --- triazoles --- CuAAC --- alkynes --- cycloalkynes --- Richter cyclization --- Suzuki coupling --- fluorescence --- cytotoxicity --- coumarin --- pyrazolo[3,4-b]pyridine --- silica sulfuric acid --- 2H-pyran --- valence isomerism --- 1-oxa-triene --- dienone --- oxa-electrocyclization --- Knoevenagel --- propargyl Claisen --- cycloisomerization --- asymmetric dimeric β-carboline --- acylhydrazone group --- cytotoxic --- antitumor --- structure–activity relationship --- γ-lactam --- pyrrolidones --- multicomponent reactions --- organocatalysis --- pyridine --- CF3CO-acetylenes --- 1,3-oxazines --- fluorinated heterocycles --- saturated oxygen heterocycles --- cyclic ethers --- total synthesis --- multicomponent reaction --- α-halohydrazones --- Staudinger reaction --- aza-Wittig --- 1H-imidazole-2(3H)-thione --- 2H-imidazo[2,1-b][1,3,4]thiadiazine --- purine --- nucleobase --- aromatic substitution --- arylation --- fluoroalcohol --- α-chloroglycinates --- 5-acylamino-1,3-thiazoles --- Hantzsch reaction --- TMSBr --- propargylic alcohols --- cascade cyclization --- 4-bromo quinolines --- synthesis of benzofurans --- intra-molecular approach --- inter-molecular approach --- n/a --- 3,2':6',3"-terpyridine --- structure-activity relationship

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