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Les infestations par les nématodes gastro-intestinaux sont encore aujourd'hui la bête noire des élevages ovins pour laquelle le moyen de lutte principal reste l'utilisation d'antiparasitaires pharmacologiques. Les pertes économiques engendrées par ces parasites sont considérables : chute de la production laitière, diminution de la vitesse de croissance, troubles de la reproduction... et entraînent les éleveurs à multiplier les traitements favorisant l'adaptation rapide des parasites et donc l'apparition de générations de nématodes multi-résistants dont Haemonchus contortus est le meilleur représentant. S'ajoute à ces considérations économiques et sanitaires, la question du respect de notre environnement. En effet, les résidus de ces produits thérapeutiques sont libérés dans l'environnement immédiat des animaux traités lorsque leurs déjections sont émises et affectent la faune et la flore en contact avec ceux-ci, réduisant ainsi la qualité des prairies. Rechercher des solutions alternatives durables est aujourd'hui une nécessité et un intérêt croissant est porté sur les nutricaments à base de plantes tanniques dont l'incorporation dans l'alimentation quotidienne des ovins permet d'obtenir un effet anthelminthique suffisant à réduire l'utilisation des antiparasitaires. Dans nos pays européens, le Sainfoin se montre prometteur puisqu'il allie qualité nutritive et propriétés anthelminthiques pour des coûts de production raisonnables. Il peut être utilisé sous toute forme : fourrages frais, foin, ensilage, pellets et donc permettre une exploitation tout au long de l'année et plus facilement adaptable aux pratiques, habitudes des éleveurs.

Nutraceutiques anthelminthique Haemonchus contortus --- Sciences du vivant > Productions animales & zootechnie

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Vache laitière --- Dairy cows --- Race indigène --- Land races --- Organisation socioéconomique --- socioeconomic organization --- Méthode statistique --- Statistical methods --- Collecte de données --- data collection --- Traitement des données --- Data processing --- Analyse de données --- Data analysis --- Donnée de production --- production data --- Étude de cas --- case studies --- Trypanosoma --- Alimentation des animaux --- Animal feeding --- Haemonchus contortus --- Afrique occidentale --- West Africa --- 636 <6> --- N'Dama cattle --- -Fouta cattle --- Futa cattle --- Cattle breeds --- Animal husbandry and breeding in general. Livestock rearing. Breeding of domestic animals--Afrika --- -Animal husbandry and breeding in general. Livestock rearing. Breeding of domestic animals--Afrika --- 636 <6> Animal husbandry and breeding in general. Livestock rearing. Breeding of domestic animals--Afrika --- Fouta cattle

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Numerous pathogens affect animal health and wellbeing and production efficiency. These pathogens also have a considerable impact on social economics, food safety and security, and human health. Infectious diseases that originate from both domesticated animals and wildlife represent one of the greatest threats to human health. Recent studies show that domesticated species harbor approximately 84 times more zoonotic viruses than wild species. Eight of the top 10 mammalian species with the highest number of zoonotic viruses are domestic, such as pigs, cattle, and horses. Many animal parasites are also zoonotic, constituting an additional burden on human health. Furthermore, the rapid emergence and spread of drug-resistant pathogen strains pose new threats to animal and human health. Climate changes will undoubtedly alter the interactions between animals and between animals and humans, which will have a huge impact on the transmission rate of existing pathogens and the emergence of new pathogens or the reemergence of old pathogens. In this special collection, interactions of all major pathogen types, including viruses, bacteria, mites and flies, protozoans, and helminths, and their hosts, such as wild and companion animals and livestock species, are discussed. Further, anthelmintic activities of natural products are evaluated. The relevance and utility of cutting-edge tools, such as immunology, genomics and genetics, microbiome studies and metabolomics, and molecular epidemiology, in dissecting host-pathogen interactions are also discussed. This special collection provides a broad knowledge base that encourages dialogue across a wide distribution of the research community in veterinary microbiology and parasitology.

Medicine --- dietary treatments --- plant bioactive compounds --- egg counts --- UHRMS --- Haemonchus contortus --- Crotalus ravus --- Crotalus triseriatus --- venom --- antibacterial activity --- Pseudomonas aeruginosa --- hemolytic activity --- maedi-visna virus --- ovine progressive pneumonia --- small ruminant lentivirus --- dairy sheep --- horse --- colic --- gastrointestinal disease --- Strongylus vulgaris --- Anoplocephala perfoliata --- cyathostominae --- D. gallinae --- hematophagous ectoparasite --- poultry red mite --- antibody titre --- lymphocyte subpopulation --- Sarcocystis spp. --- COX1 --- Camelus dromedarius --- post-mortem microbiology --- veterinary forensic pathology --- sudden death --- young dogs --- bovine digital dermatitis --- cattle lameness --- microbiome --- Treponema spp --- Ancylostoma ceylanicum --- community dogs --- ITS region --- cox1 --- Thailand --- population diversity --- Sarcoptes scabiei --- host-parasite interaction --- molecular characterization --- lipid profile --- antioxidant --- rodent --- helminth --- cestode --- trematode --- nematode --- Middle East --- meta-analysis --- Brugia pahangi --- Dirofilaria immitis --- PCR-RFLP --- spatial distribution --- altitude --- myiasis --- prevalence --- Oestrus ovis --- mtCOI --- sheep --- goats --- Saudi Arabia --- anoplocephala perfoliata --- equine --- gut microbiome --- volatile organic compounds (VOCs) --- omics integration --- tick-borne fever --- Anaplasma phagocytophilum-like 1 --- small ruminant

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Oxidative stress causes chronic diseases such as cardiovascular disease, cancer, Alzheimer, chronic obstructive pulmonary, and neurodegenerative pathologies. Antioxidant systems defend human cells from free radicals. They act by stopping free radicals, decreasing their development, and quenching the formed ROS and RNS. The antioxidant molecules are classified into primary and secondary defense molecules. The primary antioxidant molecules (i.e., vitamins C and E, ubiquinone, and glutathione) reduce oxidation effects by moving a proton to the free radical species or electron donors, or by terminating the chain reactions The secondary antioxidants (i.e., N-acetyl cysteine and lipoic acid) act as cofactors for some enzyme systems or neutralize the production of free radicals by transition metals. This work comprises original research papers and reviews on antioxidant molecules in food, the agricultural practices that maximize their levels in plants, the potential preventive effects of selected classes of antioxidant molecules, their potential use in functional foods, and the pharmaceutical delivery systems that maximize their potential activity when used as supplements.

Research & information: general --- Biology, life sciences --- Food & society --- Trichoderma spp. --- EVOO --- olive pomace --- olive vegetation water --- Olea europea var Leccino --- HRMS-Orbitrap --- phenolic identification --- antioxidant activity --- grape seed oil fatty acid --- novel extraction --- tocopherol --- supercritical fluid --- microwave assisted --- ultrasound assisted --- Soxhlet --- olive mill wastewater --- olive oil --- Olive Pâté --- antioxidants --- nutraceutical --- Q Exactive Orbitrap LC-MS/MS --- Clery strawberry --- food processing --- Polyphenols --- multi-methodological evaluation --- HS-GC/MS analysis --- PCA --- antioxidant --- HepG2 cells --- EVOO extract --- IOC methods --- LDLR --- PCSK9 --- tomatoes --- NMR spectroscopy --- FT-ICR mass spectrometry --- ripening stage --- phenolics --- metabolomics --- phytochemicals --- cardoon --- multipurpose plant --- chlorogenic acid --- fatty acids --- herbal treatment --- organic zinc --- lamb --- Haemonchus contortus --- antioxidant enzymes --- lipid peroxidation --- mineral status --- paraxanthine --- caffeine --- CYP1A2 phenotyping --- human saliva --- differential pulse voltammetry --- egg --- flavonoids --- inductively coupled plasma mass spectrometry (ICP-MS) --- metallome --- quercetin --- walnut --- by-products --- antitussive --- ROS --- NOx --- IL-6 --- CXC-R1 --- histopathological analysis --- sustainable agriculture --- onion skin --- traditional varieties --- flavonols --- dietary antioxidants, --- Helichrysum --- medicinal plants --- infusions --- phenolic compounds --- antioxidative potential --- polyphenols --- flavonids --- endogenous antioxidant enzymes --- reduced glutathione --- oxidized glutathione --- catalase --- superoxide dismutase --- interleukin 6 --- tumor necrosis factor --- endurance sports --- Ficus carica --- oxidative stress protection --- stress hormones --- epidermal skin barrier --- nutricosmetics --- brown rice --- fermentation --- germination --- stress --- bioactive compounds --- untargeted metabolomics --- functional food --- health benefits --- lovage --- elicitation --- phenolic acids --- potential anti-inflammatory potential --- anticancer properties --- antioxidative activity --- bioactive peptides --- peptidomics --- mass spectrometry --- soybean --- plant-based foods --- LDL --- CVD --- lipid oxidation --- dietary fiber --- cholesterol --- hyperlipidemia --- microalgae --- spirulina --- inflammation --- lipopolysaccharide --- dairy cows --- fattening bulls --- leukocytes --- spices --- condiments --- extra-virgin olive oil --- antiviral properties --- antioxidant properties --- nutricosmetic --- grape seed --- pomace --- polyunsaturated fatty acids --- polyphenol --- resveratrol --- rutin --- HPLC --- GC --- coumarins --- green synthesis --- DFT --- red algae --- antioxidant and antimicrobial ability --- lipoperoxidation --- salmon --- anticancer --- marigold --- sage --- bearberry --- eucalyptus --- yarrow --- apples --- pomegranate --- mitochondrial DNA --- DNA damage --- apoptosis --- oral cancer --- arbutin --- melanin --- pigment --- melasma --- skin lightening --- cosmetic --- hyperpigmentation --- tyrosinase --- nuclear factor erythroid 2-related factor 2 (Nrf2) --- Brassicaceae --- light wavelength --- reactive oxygen species (ROS) --- oxidative stress --- antioxidant proteins --- Moringa leaf extract --- nanoencapsulation --- rabbit --- physiology --- reproduction