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The search for bioactive marine natural products calls for the need of efficient chemical profiling strategies, together with the need to make advances in separation and characterization methodologies, in order to expedite their discovery. This Special Issue of Marine Drugs aims to highlight advances in extraction, isolation, purification and dereplication methodologies in the quest for bioactive marine natural products.

Chaceon quinquedens --- cold water species --- red deep-sea crab --- insulin-like androgenic gland hormone (IAG) --- androgenic gland --- bioguided-discovery --- dereplication --- cytotoxicity --- antifungal --- MS/HRMS --- marine-derived --- pimarane-type diterpenoids --- ilicicolin H --- trichothecene mycotoxins --- roridin --- verrucarin --- high-speed countercurrent chromatography --- preparative separation --- stepwise elution --- Eustigmatos cf. polyphem --- violaxanthin --- culture conditions --- purification --- antioxidant activity --- Mosher --- retroflexanone --- phloroglucinol --- HPLC-NMR --- secondary alcohol --- cephalimysins --- Aspergillus fumigatus --- marine microorganism --- Mugil cephalus --- spiro-heterocyclic γ-lactam --- circular dichroism spectroscopy --- hydroxypropyltrimethyl ammonium chloride chitosan --- halogenated acetate --- antifungal activity --- electronegativity --- microalgae --- Haematococcus pluvialis --- astaxanthin --- lutein --- fatty acids --- supercritical fluid extraction --- natural medicines --- chondroitin sulfate production --- cartilage Galeus melastomus by-products --- sulfation patterns --- process optimization --- molecular weight glycosaminoglycans determination --- bycatch waste management --- electronic circular dichroism --- absolute configuration --- molecular conformation --- electric transition dipole moment --- exciton coupling --- TDDFT calculations

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Carotenoids represent a large group of isoprenoid structures with many different structural characteristics and biological activities. They are the most important of the naturally occurring pigments and are responsible for the various colors of different fruits, vegetables, and plant parts. Marine carotenoids and their unique structures are responsible for the color of many fish, shellfish, and algae. However, while there have been many papers and reviews on carotenoids of terrestrial origin, there has been relatively little research conducted on the impact of marine carotenoids on human health. Recent research efforts have revealed that marine carotenoids have strong biological activity affecting human health and are candidates for nutraceuticals. This Topical Collection of Marine Drugs is dedicated to marine carotenoids, and will focus on the benefits of carotenoids for human beings. For a better understanding of the physiological effects of marine carotenoids, this collection should include the most recent developments in the presence, analysis, chemistry, and biochemistry of marine carotenoids.

Research & information: general --- Biology, life sciences --- fucoxanthin --- scopolamine --- acetylcholinesterase --- Alzheimer’s disease --- cognitive impairments --- mytiloxanthin --- anti-oxidative activity --- singlet oxygen --- hydroxyl radical --- lipid peroxidation --- astaxanthin production --- carotenoids --- genome-reduced Corynebacterium glutamicum --- systematic approach --- metabolic engineering --- marine microalgae --- seaweeds --- nonconventional extraction --- electrotechnologies --- pulsed electric field-assisted extraction --- supercritical fluid extraction --- green processing --- microwave-assisted extraction --- marine drugs --- Bangia fuscopurpurea --- red algae --- lycopene cyclase --- carotenoid --- metabolism --- astaxanthin --- Escherichia coli --- β-carotene ketolase --- β-carotene hydroxylase --- Haematococcus pluvialis --- PII signaling protein --- nitrogen starvation --- gene cloning --- mRNA expression --- microalgae --- anti-angiogenic --- cardioprotective activity --- anti-cancer --- anti-diabetic --- anti-inflammatory --- anti-obesity --- anti-oxidant --- beauty --- Phaeodactylum tricornutum --- spectrophotometry --- high through-put screening --- antioxidants --- bioactive compounds --- blue biotechnology --- marine microorganisms --- ozonolysis --- apo-fucoxanthinone --- Caco-2 --- antiproliferative effect --- Pyropia yezoensis --- α-cryptoxanthin --- zeinoxanthin --- lutein-5,6-epoxide --- antheraxanthin --- carotenoid synthesis pathway --- red seaweed --- human papillomavirus 16 (HPV16) --- astaxanthin (Asta) --- acrosome reaction --- cholera toxin subunit B (CTB) --- L1 protein --- cigarette smoke exposure --- p38 MAPK --- antioxidant inflammatory --- synaptic-associated plasticity --- comparative transcriptome analyses --- alcoholic liver disease --- bioinformatic analysis --- phytoene --- fluridone --- cosmeceuticals --- anti-obesity effect --- Phaeodactylum extract --- Coelastrum --- canthaxanthin --- lutein --- nanoemulsion --- sublingual delivery --- ascorbyl palmitate --- Franz cell --- alcoholic liver injury --- oxidative stress --- Nrf2 --- TLR4 --- chronic obstructive pulmonary disease --- nuclear factor erythroid 2-related factor 2 --- heme oxygenase-1 --- siphonaxanthin --- dehydro-metabolite --- white adipose tissue --- metabolic pathway in vivo --- stereochemistry --- Tigriopus --- copepod --- meso-zeaxanthin --- zeaxanthin --- reactive oxygen species --- immune system --- antioxidant --- antibiotics --- thermal stress --- disease --- halocynthiaxanthin --- intestinal absorption --- functional food --- apoptosis --- inflammation --- lipid metabolism --- high-fat diet

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Carotenoids represent a large group of isoprenoid structures with many different structural characteristics and biological activities. They are the most important of the naturally occurring pigments and are responsible for the various colors of different fruits, vegetables, and plant parts. Marine carotenoids and their unique structures are responsible for the color of many fish, shellfish, and algae. However, while there have been many papers and reviews on carotenoids of terrestrial origin, there has been relatively little research conducted on the impact of marine carotenoids on human health. Recent research efforts have revealed that marine carotenoids have strong biological activity affecting human health and are candidates for nutraceuticals. This Topical Collection of Marine Drugs is dedicated to marine carotenoids, and will focus on the benefits of carotenoids for human beings. For a better understanding of the physiological effects of marine carotenoids, this collection should include the most recent developments in the presence, analysis, chemistry, and biochemistry of marine carotenoids.

Research & information: general --- Biology, life sciences --- fucoxanthin --- scopolamine --- acetylcholinesterase --- Alzheimer’s disease --- cognitive impairments --- mytiloxanthin --- anti-oxidative activity --- singlet oxygen --- hydroxyl radical --- lipid peroxidation --- astaxanthin production --- carotenoids --- genome-reduced Corynebacterium glutamicum --- systematic approach --- metabolic engineering --- marine microalgae --- seaweeds --- nonconventional extraction --- electrotechnologies --- pulsed electric field-assisted extraction --- supercritical fluid extraction --- green processing --- microwave-assisted extraction --- marine drugs --- Bangia fuscopurpurea --- red algae --- lycopene cyclase --- carotenoid --- metabolism --- astaxanthin --- Escherichia coli --- β-carotene ketolase --- β-carotene hydroxylase --- Haematococcus pluvialis --- PII signaling protein --- nitrogen starvation --- gene cloning --- mRNA expression --- microalgae --- anti-angiogenic --- cardioprotective activity --- anti-cancer --- anti-diabetic --- anti-inflammatory --- anti-obesity --- anti-oxidant --- beauty --- Phaeodactylum tricornutum --- spectrophotometry --- high through-put screening --- antioxidants --- bioactive compounds --- blue biotechnology --- marine microorganisms --- ozonolysis --- apo-fucoxanthinone --- Caco-2 --- antiproliferative effect --- Pyropia yezoensis --- α-cryptoxanthin --- zeinoxanthin --- lutein-5,6-epoxide --- antheraxanthin --- carotenoid synthesis pathway --- red seaweed --- human papillomavirus 16 (HPV16) --- astaxanthin (Asta) --- acrosome reaction --- cholera toxin subunit B (CTB) --- L1 protein --- cigarette smoke exposure --- p38 MAPK --- antioxidant inflammatory --- synaptic-associated plasticity --- comparative transcriptome analyses --- alcoholic liver disease --- bioinformatic analysis --- phytoene --- fluridone --- cosmeceuticals --- anti-obesity effect --- Phaeodactylum extract --- Coelastrum --- canthaxanthin --- lutein --- nanoemulsion --- sublingual delivery --- ascorbyl palmitate --- Franz cell --- alcoholic liver injury --- oxidative stress --- Nrf2 --- TLR4 --- chronic obstructive pulmonary disease --- nuclear factor erythroid 2-related factor 2 --- heme oxygenase-1 --- siphonaxanthin --- dehydro-metabolite --- white adipose tissue --- metabolic pathway in vivo --- stereochemistry --- Tigriopus --- copepod --- meso-zeaxanthin --- zeaxanthin --- reactive oxygen species --- immune system --- antioxidant --- antibiotics --- thermal stress --- disease --- halocynthiaxanthin --- intestinal absorption --- functional food --- apoptosis --- inflammation --- lipid metabolism --- high-fat diet