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Biological assay. --- Carcinogenesis. --- Chlordecone. --- Carcinogens, Environmental. --- Hydrocarbons, Chlorinated. --- Insecticides --- Neoplasms --- toxicity. --- chemically induced.

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615.9 --- 615.91 --- 614.878 --- 632.95.024 --- $?$94/07 --- Environmental Exposure --- Hydrocarbons, Chlorinated --- adverse effectsy

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Environmental Exposure. --- Hydrocarbons, Chlorinated --- 615.9 --- 614.833 --- 615.91 --- 614.878 --- 632.95.024 --- $?$91/08 --- Chemische stoffen --- Exposure, Environmental --- Environmental Exposures --- Exposures, Environmental --- adverse effects. --- Produits chimiques --- Sentinel Species --- Hexachlorocyclopentadiene --- Toxicology --- Adverse effects --- Environmental aspects --- Environmental Exposure --- adverse effects

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Oncology. Neoplasms --- Toxicology --- Chlorine --- Disinfection --- Drinking. --- Water Supply. --- Neoplasms --- Water --- Kanker --- Chemische stoffen --- Supplies, Water --- Supply, Water --- Water Supplies --- Groundwater --- Water Consumption --- Water Intake --- Drinkings --- adverse effects. --- therapeutic use. --- methods. --- etiology. --- Eau --- Cancer --- Produits chimiques --- supply & distribution --- Conferences - Meetings --- Conservation of Water Resources --- Drinking water --- Purification --- Congresses --- Chlorination --- Chlorine compounds --- Cobalt --- Cobalt compounds --- Carcinogens --- Risk factors --- Drinking --- Water Supply --- adverse effects --- therapeutic use --- methods --- etiology --- WATER --- NEOPLASMS --- RISK FACTORS --- SODIUM HYPOCHLORITE --- HYDROCARBONS, CHLORINATED --- HYDROCARBONS, HALOGENATED --- COBALT --- WORLD HEALTH ORGANIZATION --- ADVERSE EFFECTS --- CHEMICALLY INDUCED

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A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity.

Trichloroethylene -- Environmental aspects. --- Trichloroethylene -- Physiological effect. --- Trichloroethylene -- Toxicology. --- Trichloroethylene --- Hydrocarbons, Chlorinated --- Hydrocarbons, Halogenated --- Hydrocarbons --- Organic Chemicals --- Chemicals and Drugs --- Public Health --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Toxicology & Public Health --- Toxicology --- Physiological effect --- Environmental aspects --- Toxicology. --- Environmental aspects. --- Physiological effect. --- Acetylene trichloride --- Ethinyl trichloride --- TCE (Trichloroethylene) --- Trethylene --- Tri (Chemical) --- Trichlorethylene --- Trichloroethene --- Triclene --- Trilene --- Trimar --- Medicine. --- Immunology. --- Molecular biology. --- Pharmacology. --- Medical biochemistry. --- Epidemiology. --- Environmental health. --- Biomedicine. --- Pharmacology/Toxicology. --- Molecular Medicine. --- Medical Biochemistry. --- Environmental Health. --- Anesthetics --- Chlorohydrocarbons --- Ethylene --- Biochemistry. --- Environmental Medicine. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Pathology --- Physicians --- Diseases --- Public health --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Composition --- Health Workforce --- Environmental quality --- Health --- Health ecology --- Environmental engineering --- Health risk assessment --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Molecular biochemistry --- Molecular biophysics --- Biophysics --- Biomolecules --- Systems biology --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Health aspects