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The Special Issue “Extractable and Non-Extractable Antioxidants” gives an updated view on antioxidants—both in their extractable and non-extractable form—in the different food groups, their products thereof, and food preparations as well as byproducts and biomass waste. The potential beneficial properties of these compounds and nutraceutical formulations are described in the various studies covered in this Special Issue.

biorefinery --- polyphenols --- polymerization --- n/a --- black teas --- nutrient --- ultrasound assisted extraction --- cyclodextrin --- HPLC-ESI/MS --- legumes --- degradation --- LC-ESI-Q-TOF-MS --- antioxidant activity --- forest residues --- multivariate analysis --- bio-based --- chemometrics --- extractable polyphenols --- extractable compounds --- pre-column HPLC method --- Cagnulari marc --- antioxidant capacity --- flour --- total polyphenol content (TPC) --- digestibility --- ferric reducing antioxidant power (FRAP) --- natural antioxidants --- dietary assessment. --- eggplant --- antioxidant --- botanicals --- anthocyanins --- trans-cinnamaldehyde --- anti-inflammation --- cereals --- functional ingredient --- food composition database --- agglomerative hierarchical clustering --- circular economy --- fermentation --- Aloysia triphylla --- Naviglio Extractor® --- flavonols glycosides --- self-inclusion --- phenolic contents --- grape seed --- integrated food research --- antioxidants --- dedicated databases --- phenolic compounds --- non-extractable compounds --- value-added by-products --- phenolic acids --- dietary supplements --- berries jam --- phenolics --- inclusion complex --- sour cherry --- Pleurotus ostreatus --- catechins --- proanthocyanidins --- Chinese mistletoes --- nuclear magnetic spectroscopy --- nitric oxide scavengers --- quercitrin --- endothelial cell --- polyphenolic compounds --- Italian popular recipes --- green extraction --- non-extractable polyphenols --- classic extraction --- study approach --- daidzein --- ?-cyclodextrin --- Camellia sinensis --- antioxidant properties --- digestive enzyme --- extractable --- bioactive compounds --- principal component analysis --- non-extractable --- oxidative stress

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Herbal and plant extracts show diverse activities and have been used for centuries as natural medicines for many health problems and diseases. Through the isolation and analysis of the compounds in the extracts, it is possible to understand why the extracts exhibit those activities, as well as the chemical metabolism of compounds that occur in plants and herbs. Recently, there have been increasing attempts to develop herbal and plant extracts into functional foods and drugs, but the legal requirements are becoming stricter. We need sophisticatedly defined extracts through the isolation and analysis of compounds comprising them in order to meet the legal requirements and to pursue quality control strategies in the production of functional foods and drugs. This Special Issue Book compiled the 15 recent research and review articles that highlight the isolation, profiling, and analysis of compounds in herbal and plant extracts, as well as quality control and standardized processing strategies for extracts with characteristic compounds.

Polygala tenuifolia --- phenolic glycosides --- saponins --- anti-inflammatory effect --- bioactive compound --- isatidis folium --- HPLC-PDA-ESI-MS/MS --- antiwrinkle activity --- quality control --- response surface methodology --- Boesenbergia rotunda --- Zingiberaceae --- flavonoid --- 4-hydroxypanduratin --- vasorelaxation --- tribe Clauseneae --- DNA barcode --- volatile compounds --- antioxidant activity --- ACE inhibitory activity --- anticancer activity --- α-glucosidase inhibitory activity --- avocado oil --- fatty acids --- hearing loss --- zebrafish --- hair cell --- Schisandra chinensis --- Omija --- dibenzocyclooctadiene lignans --- seed --- flower --- fermented beverage --- dried tepals --- total phenolic content --- total anthocyanin content --- vitamin C --- ultrasound assisted extraction --- biorefining --- fibrosarcoma --- metastasis --- natural products --- plants --- protease inhibitors --- tumor cells --- bombacoideae --- pharmacology --- phytochemical ingredients --- bioactive compounds --- medicine --- Hippophae rhamnoides --- Elaeagnaceae --- citrate derivatives --- nuclear magnetic resonance (NMR) --- electronic circular dichroism (ECD) --- Dendrobium --- Orchidaceae --- D. nobile --- D. candidum --- D. nobile × candidum --- gamma-irradiated mutant --- metabolomics --- cytotoxicity --- Morus sp. pl. --- cultivar --- mulberry --- 1-DNJ --- HPLC-ESI-MS --- HILIC --- Inonotus obliquus --- inotodiol --- noncompartment analysis --- pharmacokinetic study --- Coreopsis rosea --- Coreopsis verticillata --- mutant cultivar --- dipeptidyl peptidase-IV --- analytical tools --- data analysis --- genetically modified crops --- mass spectrometry --- metabolomics databases --- metabolomics software tools --- omics --- plant biology --- n/a

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Herbal and plant extracts show diverse activities and have been used for centuries as natural medicines for many health problems and diseases. Through the isolation and analysis of the compounds in the extracts, it is possible to understand why the extracts exhibit those activities, as well as the chemical metabolism of compounds that occur in plants and herbs. Recently, there have been increasing attempts to develop herbal and plant extracts into functional foods and drugs, but the legal requirements are becoming stricter. We need sophisticatedly defined extracts through the isolation and analysis of compounds comprising them in order to meet the legal requirements and to pursue quality control strategies in the production of functional foods and drugs. This Special Issue Book compiled the 15 recent research and review articles that highlight the isolation, profiling, and analysis of compounds in herbal and plant extracts, as well as quality control and standardized processing strategies for extracts with characteristic compounds.

Research & information: general --- Biology, life sciences --- Polygala tenuifolia --- phenolic glycosides --- saponins --- anti-inflammatory effect --- bioactive compound --- isatidis folium --- HPLC-PDA-ESI-MS/MS --- antiwrinkle activity --- quality control --- response surface methodology --- Boesenbergia rotunda --- Zingiberaceae --- flavonoid --- 4-hydroxypanduratin --- vasorelaxation --- tribe Clauseneae --- DNA barcode --- volatile compounds --- antioxidant activity --- ACE inhibitory activity --- anticancer activity --- α-glucosidase inhibitory activity --- avocado oil --- fatty acids --- hearing loss --- zebrafish --- hair cell --- Schisandra chinensis --- Omija --- dibenzocyclooctadiene lignans --- seed --- flower --- fermented beverage --- dried tepals --- total phenolic content --- total anthocyanin content --- vitamin C --- ultrasound assisted extraction --- biorefining --- fibrosarcoma --- metastasis --- natural products --- plants --- protease inhibitors --- tumor cells --- bombacoideae --- pharmacology --- phytochemical ingredients --- bioactive compounds --- medicine --- Hippophae rhamnoides --- Elaeagnaceae --- citrate derivatives --- nuclear magnetic resonance (NMR) --- electronic circular dichroism (ECD) --- Dendrobium --- Orchidaceae --- D. nobile --- D. candidum --- D. nobile × candidum --- gamma-irradiated mutant --- metabolomics --- cytotoxicity --- Morus sp. pl. --- cultivar --- mulberry --- 1-DNJ --- HPLC-ESI-MS --- HILIC --- Inonotus obliquus --- inotodiol --- noncompartment analysis --- pharmacokinetic study --- Coreopsis rosea --- Coreopsis verticillata --- mutant cultivar --- dipeptidyl peptidase-IV --- analytical tools --- data analysis --- genetically modified crops --- mass spectrometry --- metabolomics databases --- metabolomics software tools --- omics --- plant biology

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“Antioxidant Activity of Polyphenolic Plant Extracts” is a collection of scientific articles regarding polyphenols, that is, substances occurring naturally in plants and exhibiting many beneficial effects on human health. Among polyphenols’ interesting biological properties, their antioxidant activity is considered the most important. This book brings together experts from different research fields on topics related to polyphenols, such as their isolation and purification, assessment of their antioxidant activity, prevention from oxidative stress-induced diseases and use as food additives. The polyphenols used in the present studies are derived from a great variety of plants, ranging from well-known species to rare ones that are only found in specific regions. Moreover, some of the studies provide evidence that polyphenols may be used for the prevention and treatment of common diseases such as diabetes mellitus, Alzheimers’ disease, cardiovascular and intestinal diseases. Importantly, in several of the studies “green extraction methods” for the isolation of polyphenols were developed using modern technologies, where few or no organic solvents were used, in order to minimize environmental and health impacts.

Research & information: general --- Biology, life sciences --- green leafy vegetables --- effect of cooking --- polyphenols --- antioxidant activity --- Averrhoa bilimbi --- Oxalidaceae --- DPPH --- xanthine oxidase --- LC-QTOF-MS/MS --- molecular docking --- tentative bioactive constituents --- Dialium indum --- exocarp --- seed --- antioxidant --- phenolic acids --- amino acids --- GC-MS analysis --- AGN --- FIR --- phenolic --- flavonoid --- antioxidant capacity --- antimicrobial activity --- polyphenol compounds --- bixin --- rosemary extracts --- method validation --- HPLC --- food matrices --- fruit vinegar --- phenolics --- organic acid --- Ladastacho --- characterisation --- properties --- HPLC/ESI-MS --- HS-SPME/GC-MS --- beneficial use --- antimicrobial --- hydroxytyrosol --- rosemary --- pomegranate --- fish --- volatile compounds --- Rosa canina --- Rosa sempervivens --- Pyrocantha coccinea --- antioxidants --- endothelial cells --- glutathione --- almond skins --- bioavailability --- waste by-products --- flavonoids --- oxidative stress --- human --- reactive oxygen species --- proinflammatory cytokines --- Alzheimer’s disease --- cornelian cherry --- anthocyanins --- gastrointestinal digestion --- Opuntia ficus-indica cladode --- antibiofilm activity --- olive --- Olea europaea --- anthocyanin --- cyanidin 3-glucoside --- cyanidin 3-rutinoside --- oxygen radical absorbance capacity (ORAC) --- high performance liquid chromatography mass spectrometry (HPLC-MS). --- tea --- Camellia sinensis --- polyphenol --- catechin --- caffeine --- theaflavine --- insulin resistance --- diabetes --- olive oil --- phenols --- antidiabetic --- myrtle --- ultrasound-assisted extraction --- phenolic compounds --- liquid chromatography analysis --- mass spectrometry --- mulberry (Morus nigra --- Morus alba) --- simple sugars --- organic acids --- phenol compounds --- high performance liquid chromatography/diode array detector/mass spectrometry anthocyanins --- anti-inflammatory activity --- extraction --- central composite design --- optimization --- P. officinalis --- phytochemicals --- cytotoxicity --- α-amylase inhibition --- red-osier dogwood --- antioxidative effect --- H2O2 --- transepithelial resistance (TEER) --- Caco-2 cells --- Rubus idaeus L. --- HPLC-ESI-HR-qTOF-MS/MS --- antioxidant activities --- digestive enzymes inhibitors --- molecular docking analysis --- olive mill wastewater --- encapsulation --- maltodextrin --- whey protein --- gelatin --- spray drying --- diabetes mellitus --- Lamiaceae --- alpha-glucosidase --- alpha-amylase --- Salvia africana-lutea --- terpenoids --- cape floristic region --- n/a --- Alzheimer's disease --- Disaster Bay / Green Cape (NSW Far S Coast SJ55-08)

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“Antioxidant Activity of Polyphenolic Plant Extracts” is a collection of scientific articles regarding polyphenols, that is, substances occurring naturally in plants and exhibiting many beneficial effects on human health. Among polyphenols’ interesting biological properties, their antioxidant activity is considered the most important. This book brings together experts from different research fields on topics related to polyphenols, such as their isolation and purification, assessment of their antioxidant activity, prevention from oxidative stress-induced diseases and use as food additives. The polyphenols used in the present studies are derived from a great variety of plants, ranging from well-known species to rare ones that are only found in specific regions. Moreover, some of the studies provide evidence that polyphenols may be used for the prevention and treatment of common diseases such as diabetes mellitus, Alzheimers’ disease, cardiovascular and intestinal diseases. Importantly, in several of the studies “green extraction methods” for the isolation of polyphenols were developed using modern technologies, where few or no organic solvents were used, in order to minimize environmental and health impacts.

Research & information: general --- Biology, life sciences --- green leafy vegetables --- effect of cooking --- polyphenols --- antioxidant activity --- Averrhoa bilimbi --- Oxalidaceae --- DPPH --- xanthine oxidase --- LC-QTOF-MS/MS --- molecular docking --- tentative bioactive constituents --- Dialium indum --- exocarp --- seed --- antioxidant --- phenolic acids --- amino acids --- GC-MS analysis --- AGN --- FIR --- phenolic --- flavonoid --- antioxidant capacity --- antimicrobial activity --- polyphenol compounds --- bixin --- rosemary extracts --- method validation --- HPLC --- food matrices --- fruit vinegar --- phenolics --- organic acid --- Ladastacho --- characterisation --- properties --- HPLC/ESI-MS --- HS-SPME/GC-MS --- beneficial use --- antimicrobial --- hydroxytyrosol --- rosemary --- pomegranate --- fish --- volatile compounds --- Rosa canina --- Rosa sempervivens --- Pyrocantha coccinea --- antioxidants --- endothelial cells --- glutathione --- almond skins --- bioavailability --- waste by-products --- flavonoids --- oxidative stress --- human --- reactive oxygen species --- proinflammatory cytokines --- Alzheimer's disease --- cornelian cherry --- anthocyanins --- gastrointestinal digestion --- Opuntia ficus-indica cladode --- antibiofilm activity --- olive --- Olea europaea --- anthocyanin --- cyanidin 3-glucoside --- cyanidin 3-rutinoside --- oxygen radical absorbance capacity (ORAC) --- high performance liquid chromatography mass spectrometry (HPLC-MS). --- tea --- Camellia sinensis --- polyphenol --- catechin --- caffeine --- theaflavine --- insulin resistance --- diabetes --- olive oil --- phenols --- antidiabetic --- myrtle --- ultrasound-assisted extraction --- phenolic compounds --- liquid chromatography analysis --- mass spectrometry --- mulberry (Morus nigra --- Morus alba) --- simple sugars --- organic acids --- phenol compounds --- high performance liquid chromatography/diode array detector/mass spectrometry anthocyanins --- anti-inflammatory activity --- extraction --- central composite design --- optimization --- P. officinalis --- phytochemicals --- cytotoxicity --- α-amylase inhibition --- red-osier dogwood --- antioxidative effect --- H2O2 --- transepithelial resistance (TEER) --- Caco-2 cells --- Rubus idaeus L. --- HPLC-ESI-HR-qTOF-MS/MS --- antioxidant activities --- digestive enzymes inhibitors --- molecular docking analysis --- olive mill wastewater --- encapsulation --- maltodextrin --- whey protein --- gelatin --- spray drying --- diabetes mellitus --- Lamiaceae --- alpha-glucosidase --- alpha-amylase --- Salvia africana-lutea --- terpenoids --- cape floristic region --- Disaster Bay / Green Cape (NSW Far S Coast SJ55-08)