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This book is a concise review of medically important applications of Human Leukocyte Antigen (HLA) in medicine. It covers both basic knowledge of HLA and its main clinical applications in medical practice. Its two major aims are to assist students who are preparing for clinical immunology examinations, and to help people who want to understand more about this subject with brief and flexible sources of information. This book presents current, medically important information on the rapidly changing field of tissue typing and its relation with diseases. It includes updated information on such topics as tissue typing in medicine and transplant immunology.

HLA histocompatibility antigens. --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Histocompatibility antigens --- Major histocompatibility complex --- Immunology

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The processing and presentation of antigens by major histocompatibility complex (MHC) molecules is a crucial immunological phenomenon in infectious disease, malignancy, autoimmune disease, and transplantation. In Antigen Processing and Presentation Protocols, well-recognized and innovative experimentalists detail their cutting-edge methods for studying this complex process. Drawing on expertise from biochemistry, cell biology, and immunology, they describe step-by-step methods designed to question how MHC-binding peptides are generated, to test how peptides are delivered to MHC molecules, to analyze MHC peptide-binding patterns, and to assay the T cell response to the MHC/peptide complex. Each method is presented in sufficient detail to be readily reproducible and includes notes about potential pitfalls and tips on how to avoid failures. Emphasis is given those technical steps critical for experimental success that are often omitted from methods published in the primary literature. Eminently accessible and state-of-the-art, Antigen Processing and Presentation Protocols provides both new and experienced investigators with highly practical tools that will extend the questions that can be asked, and effectively be answered, concerning antigen processing/presentation.

Molecular biology --- Antigen presenting cells --- Antigens --- HLA histocompatibility antigens --- Major histocompatibility complex --- Molecular immunology --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Histocompatibility antigens --- Immunity --- Immunoglobulins --- Immune system --- Immunology --- Accessory cells --- Immunologic accessory cells --- Immunocompetent cells --- Histocompatibility complex --- MHC (Immunogenetics) --- Immunogenetics --- Molecular aspects --- Immunology. --- Immunobiology --- Life sciences --- Serology

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A volume in the popular FactsBook Series, the First Edition of The Leucocyte Antigen FactsBook was hugely successful. The new Second Edition has been completely revised, updated, and expanded by 65% to include new findings and up-to-date key references. The introductory chapters have also been updated, especially in terms of nomenclature, the role of the World Wide Web, and new structural data. The Leucocyte Antigen FactsBook, Second Edition contains more than 200 entries, with approximately 70 new entries, on all the molecules specifically expressed in the surface of cells of the haematopoietic system, including all characterized CD antigens, antigen receptors, MHC antigens, adhesion molecules, and cytokine receptors. This FactsBook will be of enormous value to immunologists, cell biologists, biochemists, and endocrinologists.

CD antigens --- HLA histocompatibility antigens --- Leucocytes --- Antigens, CD --- CD glycoproteins --- CD molecules --- CD receptors --- CD surface immunoglobulin ligands --- Differentiation antigens, Human leukocyte --- Human leukocyte differentiation antigens --- Leukocyte differentiation antigens, Human --- Leukocytes --- White blood cells --- White cells --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Cell surface antigens --- Fc receptors --- Glycoproteins --- Blood cells --- Killer cells --- Histocompatibility antigens --- Major histocompatibility complex --- Handbooks, manuals, etc

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HLA histocompatibility antigens --- Leucoagglutinins --- Leucocytes --- HLA histocompatibility antigens. --- Leucoagglutinins. --- Leucocytes. --- HLA Antigens. --- Histocompatibility Antigens. --- Immunity. --- Disease --- Antigens, Transplantation --- Histocompatibility Antigen --- LD Antigens --- SD Antigens --- Transplantation Antigens --- Antigen, Histocompatibility --- Antigens, Histocompatibility --- Antigens, LD --- Antigens, SD --- HL-A Antigens --- Human Leukocyte Antigens --- Leukocyte Antigens --- Antigens, HL-A --- Antigens, HLA --- Antigens, Human Leukocyte --- Antigens, Leukocyte --- HL A Antigens --- Leukocyte Antigens, Human --- Leukocytes --- White blood cells --- White cells --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Leuko-agglutinins --- immunology --- Immunoglobulins --- Blood cells --- Killer cells --- Agglutinins --- Histocompatibility antigens --- Major histocompatibility complex --- Immune Process --- Immune Response --- Immune Processes --- Immune Responses --- Process, Immune --- Response, Immune --- Human Leukocyte Antigen --- Antigen, Human Leukocyte --- Leukocyte Antigen, Human --- HLA Antigens --- Histocompatibility Antigens --- Immunity

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Immunology. Immunopathology --- HLA histocompatibility antigens --- Antigens, CD --- Cell Adhesion Molecules --- Handbooks, manuals, etc --- Antigens, CD. --- Cell Adhesion Molecules. --- -616-097 --- 577.27 --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Histocompatibility antigens --- Major histocompatibility complex --- Saccharide Mediated Cell Adhesion Molecules --- Intercellular Adhesion Molecules --- Leukocyte Adhesion Molecules --- Saccharide-Mediated Cell Adhesion Molecules --- Adhesion Molecules, Cell --- Adhesion Molecules, Intercellular --- Adhesion Molecules, Leukocyte --- Molecules, Cell Adhesion --- Molecules, Intercellular Adhesion --- Molecules, Leukocyte Adhesion --- Integrins --- Cluster of Differentiation Antigens --- Cluster of Differentiation Markers --- Differentiation Antigens, Leukocyte, Human --- Leukocyte Differentiation Antigens, Human --- CD Antigens --- Antigens. Antibodies --- Molecular bases of immunity. Molecular immunology --- Antigens. --- CD antigens --- HLA Antigens --- Handbooks, manuals, etc. --- handbooks. --- 577.27 Molecular bases of immunity. Molecular immunology --- 616-097 Antigens. Antibodies --- Antigens, cd --- Cd antigens --- Hla antigens --- Hla histocompatibility antigens --- Handbooks. --- 616-097 --- CD glycoproteins --- CD molecules --- CD receptors --- CD surface immunoglobulin ligands --- Differentiation antigens, Human leukocyte --- Human leukocyte differentiation antigens --- Leukocyte differentiation antigens, Human --- Cell surface antigens --- Fc receptors --- Glycoproteins --- LEUCOCYTES --- Monograph --- Leucocytes. --- Leukocytes --- White blood cells --- White cells --- Blood cells --- Killer cells --- Cell Adhesion Molecule --- Intercellular Adhesion Molecule --- Leukocyte Adhesion Molecule --- Adhesion Molecule, Cell --- Adhesion Molecule, Intercellular --- Adhesion Molecule, Leukocyte --- Molecule, Cell Adhesion --- Molecule, Intercellular Adhesion --- Molecule, Leukocyte Adhesion --- CD Antigen --- Cluster of Differentiation Antigen --- Cluster of Differentiation Marker --- Antigen Cluster, Differentiation --- Antigen, CD --- Differentiation Antigen Cluster --- Differentiation Marker Cluster --- Marker Cluster, Differentiation