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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Endocrinology --- obesity --- diabetes --- adipose tissue --- body composition --- TRPV1 - transient receptor potential vanilloid type 1 receptor --- PPAR gamma --- HIV --- hepatocyte growth factor (HGF)

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Endocrinology --- obesity --- diabetes --- adipose tissue --- body composition --- TRPV1 - transient receptor potential vanilloid type 1 receptor --- PPAR gamma --- HIV --- hepatocyte growth factor (HGF) --- obesity --- diabetes --- adipose tissue --- body composition --- TRPV1 - transient receptor potential vanilloid type 1 receptor --- PPAR gamma --- HIV --- hepatocyte growth factor (HGF)

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No area of cancer supportive care better illustrates the advances in our understanding of cellular and molecular biology, genetic engineering and the development of more effective yet often more toxic cancer treatments than that of hematopoietic growth factors. Myelosuppressive agents, with their potential hematopoietic toxicities, remain the mainstay of systemic treatment for both metastatic and early stage cancer. Hematopoietic Growth Factors in Oncology reviews and integrates the major advances in our understanding of the underlying molecular biology and pharmacology of these agents along with the results of well designed and executed randomized controlled trials of the erythroid stimulating agents, the myeloid growth factors and the new thrombopoietic agents, each addressing a major threat associated with bone marrow suppression accompanying cancer treatment. "Hematopoietic growth factors have revolutionized the treatment of patients with a spectrum of cancers and benign bone marrow disorders. This text addresses the mechanism of action and clinical impact of these cytokines. Leading investigators in the field provide and update of current state of knowledge and future challenges." – Steven T. Rosen, M.D. Series Editor.

Cancer -- Chemotherapy. --- Electronic books. -- local. --- Hematopoietic growth factors -- Therapeutic use. --- Hematopoietic growth factors --- Oncology --- Hematopoietic Cell Growth Factors --- Diseases --- Glycoproteins --- Biological Science Disciplines --- Therapeutics --- Proteins --- Natural Science Disciplines --- Cytokines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Colony-Stimulating Factors --- Drug Therapy --- Neoplasms --- Pharmacology --- Amino Acids, Peptides, and Proteins --- Intercellular Signaling Peptides and Proteins --- Disciplines and Occupations --- Peptides --- Chemicals and Drugs --- Biological Factors --- Medicine --- Health & Biological Sciences --- Mechanism of action --- Cancer --- Therapeutic use. --- Chemotherapy. --- Hematopoietic cell growth factors --- Hematopoietins --- HGF (Growth factors) --- Medicine. --- Oncology. --- Medicine & Public Health. --- Antineoplastic agents --- Growth factors --- Treatment --- Oncology  . --- Tumors

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This book is a compilation of articles by experts on the prevention and treatment of periodontal disease, many of which are full of data-based evidence from basic research perspectives or patient data.

70-kDa heat shock proteins --- gingival crevicular fluid --- heat shock protein --- periodontitis --- periodontal disease --- diabetes --- diabetic retinopathy --- bleeding on probing --- probing pocket depth --- fasting blood sugar --- carotid artery calcification --- alveolar bone loss --- computed tomography --- panoramic radiographs --- aspiration pneumonia --- chronic periodontitis --- Porphyromonas gingivalis --- proinflammatory cytokines --- TLR2 --- epidemiological index --- item response theory --- oral examination --- diagnosis --- Mfa1 --- Toll-like receptors --- gingival fibroblast --- azithromycin --- human gingival fibroblast --- human periodontal ligament fibroblast --- IL-6 --- IL-8 --- MMP-1 --- MMP-2 --- chewing ability --- infection --- inflammation --- periodontal medicine --- Gan-Lu-Yin --- herbal medicine --- osteoclastogenesis --- periodontal diseases --- periodontal pocket --- health status indicators --- periodontal inflamed surface area (PISA) --- rheumatoid arthritis --- tocilizumab --- periodontal inflamed surface area --- periodontal pathogen --- mixed effect modeling --- follow-up study --- Low reactive Level Laser Therapy (LLLT) --- human gingival fibroblasts (HGF) --- microarray --- differentially gene expression (DEGs) --- gene ontology --- biological processes (BP) --- protein–protein interaction (PPI)

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Human lactation has evolved to produce a milk composition that is uniquely-designed for the human infant. Not only does human milk optimize infant growth and development, it also provides protection from infection and disease. More recently, the importance of human milk and breastfeeding in the programming of infant health has risen to the fore. Anchoring of infant feeding in the developmental origins of health and disease has led to a resurgence of research focused in this area. Milk composition is highly variable both between and within mothers. Indeed the distinct maternal human milk signature, including its own microbiome, is influenced by environmental factors, such as diet, health, body composition and geographic residence. An understanding of these changes will lead to unravelling the adaptation of milk to the environment and its impact on the infant. In terms of the promotion of breastfeeding, health economics and epidemiology is instrumental in shaping public health policy and identifying barriers to breastfeeding. Further, basic research is imperative in order to design evidence-based interventions to improve both breastfeeding duration and women’s breastfeeding experience.

Cambodia --- milk metabolomics --- galactogogues --- adequate intake --- postnatal outcomes --- cytomegalovirus --- midwifery --- milk synthesis --- chromatography --- protein --- lactoferrin --- human lactation --- ultrasound skinfolds --- breastfed infants --- knowledge --- pregnancy --- casein --- SEA --- maternal factors --- ethnicity --- post-partum distress --- bottle --- composition --- feeding --- co-sleeping --- passive immunity --- glycerophosphocholine --- anthropometrics --- antimicrobial proteins --- professional support --- mothers of preterm infants --- responsive feeding --- lactating women --- peptidomics --- triiodothyronine --- preterm --- mother–infant physical contact --- expressing --- preterm infant --- appetite regulation --- justification of supplementation --- body composition --- zinc supplementation --- antibodies --- antisecretory factor --- proteolysis --- enteral nutrition --- Ecuador --- growth factors --- maternal responsiveness --- maternal wellbeing --- nipple shield --- microbiome --- maternal distress --- sodium --- thyroid --- maternal diet --- thyroxine --- IgA --- caesarean section --- raw breast milk --- colostrum --- fatty acids --- breast milk --- immune cells --- metabolites --- PEA --- premature --- mode of delivery --- endocannabinoids --- lipids --- practice --- fat synthesis --- attitudes --- feeding cues --- infant --- Docosahexaenoic acid --- Arachidonic acid --- GDM --- milk-acquired infections --- zinc deficiency --- ICP-OES --- social support --- infants --- omega-6 fatty acids --- infant health --- HGF --- omega-3 fatty acids --- OEA --- leptin --- milk metabolites --- Canada --- mother–infant interaction --- NMR spectroscopy --- lipidomics --- infection --- breastfeeding support --- prematurity --- phosphocholine --- immunity --- Quito --- sex-specificity --- choline --- paternal role --- inflammation --- docosahexaenoic acid --- partner support --- proximal care --- thyroid antibodies --- adipokines --- calculated daily intakes --- candida --- proton nuclear magnetic resonance --- N-acylethanolamines --- milk intake --- whey --- bioelectrical impedance spectroscopy --- breastfeeding --- n-6 and n-3 polyunsaturated fatty acid --- babywearing --- milk composition --- breastmilk --- obesity --- lactation --- infant growth --- formula supplementation --- early life nutrition --- adiponectin --- milk cells --- potassium --- human milk --- long-chain polyunsaturated fatty acids --- Andean region --- Ireland --- mass spectrometry --- geographical location --- diet --- dietary recommendations --- TGF-? --- ion selective electrode --- plasma zinc --- barriers --- infant feeding --- human milk composition --- Breastfeeding