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The book provides a comprehensive overview of nanostructures and methods used to design biosensors, as well as applications for these biosensor nanotechnologies in the biological, chemical, and environmental monitoring fields. Biological sensing has proven to be an essential tool for understanding living systems, but it also has practical applications in medicine, drug discovery, food safety, environmental monitoring, defense, personal security, etc. In healthcare, advancements in telecommunications, expert systems, and distributed diagnostics are challenging current delivery models, while robust industrial sensors enable new approaches to research and development. Experts from around the world have written five articles on topics including:Diagnosing and treating intraocular cancers such as retinoblastoma; Nanomedicine in cancer management; Engineered nanomaterials in osteosarcoma diagnosis and treatment; Practical design of nanoscale devices; Detect alkaline phosphatase quantitatively in clinical diagnosis; Progress in the area of non-enzymatic sensing of dual/multi biomolecules; Developments in non-enzymatic glucose and H2O2 (NEGH) sensing; Multi-functionalized nanocarrier therapies for targeting retinoblastoma; Galactose functionalized nanocarriers; Sensing performance, electro-catalytic mechanism, and morphology and design of electrode materials; Biosensors along with their applications and the benefits of machine learning; Innovative approaches to improve the NEGH sensitivity, selectivity, and stability in real-time applications; Challenges and solutions in the field of biosensors.

Technology: general issues --- advanced nanomaterials --- dual in-line sensing --- bi-functional properties --- non-enzymatic --- electrochemical sensing --- glucose and H2O2 --- nanotechnology --- bone diseases --- drug delivery --- nanocarriers --- osteosarcoma --- tumor-targeted --- retinoblastoma --- rare cancer --- surface-tailored multi-functionalized nanoparticles --- metallic nanoparticle --- tumor-suppressor gene mutation --- alkaline phosphatase --- terminal protection --- copper nanoparticle --- fluorescence --- biosensor --- electrochemical --- sensitivity --- amperometric --- voltammetric --- food quality monitoring --- machine learning --- n/a

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The book provides a comprehensive overview of nanostructures and methods used to design biosensors, as well as applications for these biosensor nanotechnologies in the biological, chemical, and environmental monitoring fields. Biological sensing has proven to be an essential tool for understanding living systems, but it also has practical applications in medicine, drug discovery, food safety, environmental monitoring, defense, personal security, etc. In healthcare, advancements in telecommunications, expert systems, and distributed diagnostics are challenging current delivery models, while robust industrial sensors enable new approaches to research and development. Experts from around the world have written five articles on topics including:Diagnosing and treating intraocular cancers such as retinoblastoma; Nanomedicine in cancer management; Engineered nanomaterials in osteosarcoma diagnosis and treatment; Practical design of nanoscale devices; Detect alkaline phosphatase quantitatively in clinical diagnosis; Progress in the area of non-enzymatic sensing of dual/multi biomolecules; Developments in non-enzymatic glucose and H2O2 (NEGH) sensing; Multi-functionalized nanocarrier therapies for targeting retinoblastoma; Galactose functionalized nanocarriers; Sensing performance, electro-catalytic mechanism, and morphology and design of electrode materials; Biosensors along with their applications and the benefits of machine learning; Innovative approaches to improve the NEGH sensitivity, selectivity, and stability in real-time applications; Challenges and solutions in the field of biosensors.

Technology: general issues --- advanced nanomaterials --- dual in-line sensing --- bi-functional properties --- non-enzymatic --- electrochemical sensing --- glucose and H2O2 --- nanotechnology --- bone diseases --- drug delivery --- nanocarriers --- osteosarcoma --- tumor-targeted --- retinoblastoma --- rare cancer --- surface-tailored multi-functionalized nanoparticles --- metallic nanoparticle --- tumor-suppressor gene mutation --- alkaline phosphatase --- terminal protection --- copper nanoparticle --- fluorescence --- biosensor --- electrochemical --- sensitivity --- amperometric --- voltammetric --- food quality monitoring --- machine learning

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This book, entitled “Mesoporous Metal Oxide Films”, contains an editorial and a collection of ten research articles covering fundamental studies and applications of different metal oxide films. Mesoporous materials have been widely investigated and applied in many technological applications owing to their outstanding structural and physical properties. In this book, important developments in this fast-moving field are presented from various research groups around the world. Different preparation methods and applications of these novel and interesting materials have been reported, and it was demonstrated that mesoporosity has a direct impact on the properties and potential applications of such materials. The potential use of mesoporous metal oxide films and coatings with different morphology and structures is demonstrated in many technological applications, particularly chemical and electrochemical sensors, supercapacitors, solar cells, photoelectrodes, bioceramics, photonic switches, and anticorrosion agents.

History of engineering & technology --- SnO2 --- Metglas --- hemin --- H2O2 --- cyclic voltammetry --- magnetoelastic resonance --- sensor --- titanium dioxide --- mesoporous --- thin film --- multi-layered --- photoanode --- semiconductor --- photoelectrochemical water oxidation --- Mn2O3 --- mesoporous materials --- electrochemical characterizations --- electrode --- supercapacitors --- gadolinium oxide --- hydrazine --- p-nitrophenol --- electrochemical sensing --- amperometric --- selective sensor --- nanocrystal --- ZnO --- density of states --- optical and electrical properties --- TiO2 films --- Ag nanoparticles --- optical properties --- spectroelectrochemistry --- surface plasmon --- Fe-doped TiO2 --- hydrothermal --- GCE --- chemical sensor --- amperometry --- dye-sensitized solar cells --- working electrode --- TiO2 --- NiO nanoparticles --- electron transport --- corrosion --- guar gum --- coatings --- electrochemical impedance spectroscopy (EIS) --- SECM --- AFM --- calcium phosphate silicate --- PEG --- bioceramics --- sol-gel preparation --- hard tissue engineering --- metal oxide --- sol-gel --- supercapacitor --- photoelectrode --- dye sensitized solar cell --- NiO

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This book, entitled “Mesoporous Metal Oxide Films”, contains an editorial and a collection of ten research articles covering fundamental studies and applications of different metal oxide films. Mesoporous materials have been widely investigated and applied in many technological applications owing to their outstanding structural and physical properties. In this book, important developments in this fast-moving field are presented from various research groups around the world. Different preparation methods and applications of these novel and interesting materials have been reported, and it was demonstrated that mesoporosity has a direct impact on the properties and potential applications of such materials. The potential use of mesoporous metal oxide films and coatings with different morphology and structures is demonstrated in many technological applications, particularly chemical and electrochemical sensors, supercapacitors, solar cells, photoelectrodes, bioceramics, photonic switches, and anticorrosion agents.

SnO2 --- Metglas --- hemin --- H2O2 --- cyclic voltammetry --- magnetoelastic resonance --- sensor --- titanium dioxide --- mesoporous --- thin film --- multi-layered --- photoanode --- semiconductor --- photoelectrochemical water oxidation --- Mn2O3 --- mesoporous materials --- electrochemical characterizations --- electrode --- supercapacitors --- gadolinium oxide --- hydrazine --- p-nitrophenol --- electrochemical sensing --- amperometric --- selective sensor --- nanocrystal --- ZnO --- density of states --- optical and electrical properties --- TiO2 films --- Ag nanoparticles --- optical properties --- spectroelectrochemistry --- surface plasmon --- Fe-doped TiO2 --- hydrothermal --- GCE --- chemical sensor --- amperometry --- dye-sensitized solar cells --- working electrode --- TiO2 --- NiO nanoparticles --- electron transport --- corrosion --- guar gum --- coatings --- electrochemical impedance spectroscopy (EIS) --- SECM --- AFM --- calcium phosphate silicate --- PEG --- bioceramics --- sol-gel preparation --- hard tissue engineering --- metal oxide --- sol-gel --- supercapacitor --- photoelectrode --- dye sensitized solar cell --- NiO

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ROS were long considered one of the key players in tissue injury. Indeed, overproduction of ROS results in oxidative stress, a process leading to the development of many pathological conditions. For the treatment of these conditions, the use of antioxidants was proposed. Over time, it was shown that ROS at low concentrations act as signaling molecules, leading to the regulation of physiological functions. Moreover, several interventions that increase ROS generation activate stress-adaptive responses that extend the lifespan. It was also shown that excessive use of antioxidants can counter the beneficial effects of ROS. Currently, much progress has been made in understanding the role of ROS in human diseases and aging, as well as in the regulation of physiological functions, and in identifying the signaling pathways involved in ROS. However, much remains to be understood about the mutual interactions among signaling pathways underlying organisms’ adaptive responses, their modifications (which occur during aging), and some disease states. The aim of this Special Issue is to underline the effects of ROS production and antioxidant treatment in living organisms, focusing on their impact on health, disease, and aging.

Research & information: general --- Biology, life sciences --- CTCL --- apoptosis --- cell viability --- c-FLIP --- XIAP --- artemisinin --- SH-SY5Y cells --- hippocampal neurons --- H2O2 --- AMPK pathway --- atherosclerosis --- sphingomyelin synthase 2 --- endothelial dysfunction --- endoplasmic reticulum stress --- β-catenin --- insulin resistance --- cancer --- cardiovascular disease --- neurodegenerative disorders --- exercise --- mitochondria --- oxidative stress --- PGC-1 --- Nrf2 --- UCPs --- ROS --- light --- DNA damage --- evolution --- D-box --- cavefish --- Spalax --- trimethylamine N-oxide --- cardiomyocytes --- cardiotoxicity --- mitochondrial membrane potential --- CORM-2 --- NADPH oxidase --- AP-1 --- HO-1 --- Renal cell carcinoma (RCC) --- reactive oxygen species (ROS) --- glutathione (GSH) metabolism --- cancer therapy --- clear cell RCC --- papillary RCC --- chromophobe RCC --- sarcopenia --- reactive oxygen species --- redox signaling --- antioxidant supplementation --- protein aggregation --- redox --- proteinopathy --- peroxiredoxins --- tumorigenesis --- ROS scavengers