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As plant-based foods, both vegetables and fruits have been clearly associated with the presence of high amounts of bioactive compounds, and have been demonstrated as having a central role in the prevention of diseases. Many scientists of different research fields have lavished great effort both to characterize the bioactive compounds’ compositions and to deepen understanding regarding the mechanisms of action through which fruits and vegetables exert their health-promoting and/or disease-preventing properties. In this book, studies on the bioactive compounds’ composition of the main fruit and vegetable species, on their health effects as fresh-consumed, transformed products or applied in in vitro models, and on their mechanisms of actions against human pathologies are presented.

Research & information: general --- Biology, life sciences --- Technology, engineering, agriculture --- ABTS --- bioactive compounds --- DPPH --- flavonoids --- genetic distance --- genotypic and phenotypic correlation --- nutraceutical value --- phenolics --- UPGMA --- apricot --- methyl jasmonate --- salicylic acid --- antioxidant property --- enzyme activity --- postharvest quality --- elderberry --- reishi --- respiratory tract infections --- common cold --- influenza-like illness --- respiratory infection symptoms --- randomized controlled trial --- agrobiodiversity --- antioxidant activity --- health benefits --- medicinal properties --- Mediterranean diet --- market food trends --- sustainability --- wild edible greens --- organic farming --- conventional farming --- trace elements --- heavy metals --- risk assessment --- anthocyanins --- Fragaria × ananassa --- latitude --- temperature --- global radiation --- cultivar × environmental interaction --- phytochemical compounds --- antioxidant capacity --- Brassica spp. --- vegetables --- cultivation techniques --- glucosinolates --- apple --- royal gala --- pink lady --- red delicious --- smitten --- fuji --- phenolic compounds --- LC-ESI-QTOF-MS/MS --- HPLC --- garlic --- Allium sativum --- thiosulfinate --- allicin --- sepsis --- immunomodulation --- interleukins --- rats --- hydroxytyrosol --- olive extract --- olive polyphenols --- grape extract --- oleuropein --- F2-isoprostanes --- AGEs --- Gynura bicolor --- prediabetes --- phytochemical --- blood glucose --- oxidative stress --- n/a

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As plant-based foods, both vegetables and fruits have been clearly associated with the presence of high amounts of bioactive compounds, and have been demonstrated as having a central role in the prevention of diseases. Many scientists of different research fields have lavished great effort both to characterize the bioactive compounds’ compositions and to deepen understanding regarding the mechanisms of action through which fruits and vegetables exert their health-promoting and/or disease-preventing properties. In this book, studies on the bioactive compounds’ composition of the main fruit and vegetable species, on their health effects as fresh-consumed, transformed products or applied in in vitro models, and on their mechanisms of actions against human pathologies are presented.

Research & information: general --- Biology, life sciences --- Technology, engineering, agriculture --- ABTS --- bioactive compounds --- DPPH --- flavonoids --- genetic distance --- genotypic and phenotypic correlation --- nutraceutical value --- phenolics --- UPGMA --- apricot --- methyl jasmonate --- salicylic acid --- antioxidant property --- enzyme activity --- postharvest quality --- elderberry --- reishi --- respiratory tract infections --- common cold --- influenza-like illness --- respiratory infection symptoms --- randomized controlled trial --- agrobiodiversity --- antioxidant activity --- health benefits --- medicinal properties --- Mediterranean diet --- market food trends --- sustainability --- wild edible greens --- organic farming --- conventional farming --- trace elements --- heavy metals --- risk assessment --- anthocyanins --- Fragaria × ananassa --- latitude --- temperature --- global radiation --- cultivar × environmental interaction --- phytochemical compounds --- antioxidant capacity --- Brassica spp. --- vegetables --- cultivation techniques --- glucosinolates --- apple --- royal gala --- pink lady --- red delicious --- smitten --- fuji --- phenolic compounds --- LC-ESI-QTOF-MS/MS --- HPLC --- garlic --- Allium sativum --- thiosulfinate --- allicin --- sepsis --- immunomodulation --- interleukins --- rats --- hydroxytyrosol --- olive extract --- olive polyphenols --- grape extract --- oleuropein --- F2-isoprostanes --- AGEs --- Gynura bicolor --- prediabetes --- phytochemical --- blood glucose --- oxidative stress --- ABTS --- bioactive compounds --- DPPH --- flavonoids --- genetic distance --- genotypic and phenotypic correlation --- nutraceutical value --- phenolics --- UPGMA --- apricot --- methyl jasmonate --- salicylic acid --- antioxidant property --- enzyme activity --- postharvest quality --- elderberry --- reishi --- respiratory tract infections --- common cold --- influenza-like illness --- respiratory infection symptoms --- randomized controlled trial --- agrobiodiversity --- antioxidant activity --- health benefits --- medicinal properties --- Mediterranean diet --- market food trends --- sustainability --- wild edible greens --- organic farming --- conventional farming --- trace elements --- heavy metals --- risk assessment --- anthocyanins --- Fragaria × ananassa --- latitude --- temperature --- global radiation --- cultivar × environmental interaction --- phytochemical compounds --- antioxidant capacity --- Brassica spp. --- vegetables --- cultivation techniques --- glucosinolates --- apple --- royal gala --- pink lady --- red delicious --- smitten --- fuji --- phenolic compounds --- LC-ESI-QTOF-MS/MS --- HPLC --- garlic --- Allium sativum --- thiosulfinate --- allicin --- sepsis --- immunomodulation --- interleukins --- rats --- hydroxytyrosol --- olive extract --- olive polyphenols --- grape extract --- oleuropein --- F2-isoprostanes --- AGEs --- Gynura bicolor --- prediabetes --- phytochemical --- blood glucose --- oxidative stress

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Plant alkaloids are critical components of modern medicine and pharmaceuticals. These compounds are also becoming increasingly important for industrial uses as part of the green chemistry revolution. This Special Issue will focus on the molecular advances being made in understanding how such a large and diverse class of compounds are made by plants and how metabolic engineering advances are increasing the overall yield of crucial precursors.

canthin-6-one --- Picrolemma huberi --- Simaroubaceae --- antiplasmodial activity --- Sarcococca hookeriana --- sarchookloides A–C --- steroidal alkaloid --- cytotoxicity --- Rhodophiala --- alkaloids --- molecular docking --- AChE --- BuChE --- GC-MS --- Mahonia imbricata --- Berberidaceae --- isoquinoline alkaloid --- mahimbrine A --- hedgehog signaling --- Veratrum californicum --- cyclopamine --- HPLC-MS --- Shh-Light II cells --- halogencyclopropane --- dichlorocarbene --- epoxidation --- vindoline --- catharanthine --- dimer alkaloids --- vindoline trimer --- Ruta graveolens --- photosystem II --- Chl a fluorescence --- Hill reaction inhibitors --- acridone alkaloids --- benzylisoquinoline alkaloids --- cytochrome P450 monooxygenase --- medicinal properties --- methyltransferase --- Nelumbo nucifera --- norcoclaurine synthase --- sacred lotus --- stereochemistry --- Aristotelia chilensis Molina Stuntz --- vascular activity --- endothelium-independent --- indole alkaloid --- 8-oxo-9-dihydromakomakine --- voltage-dependent calcium channels --- Catharanthus roseus --- cambial meristematic cells --- Aspergillus flavus --- terpenoid indole alkaloids --- biosynthesis --- Buxaceae --- Borago officinalis --- Crassocephalum --- Copper-dependent diamine oxidase --- Gynura bicolor --- Homospermidine synthase --- Lolium perenne --- Necic acids --- Necine bases --- Pyrrolizidine alkaloid biosynthesis --- Senecionine --- tropane alkaloids --- scopolamine --- cocaine --- calystegine --- chemistry --- pharmacology --- biotechnological production --- Erythroxylaceae --- Erythroxylum coca --- next generation sequencing --- traditional medicine --- bioprospecting --- tropane --- late-stage functionalization --- sulfinate --- DiversinateTM --- natural product --- medicinal chemistry --- papaverine --- scaffold --- library --- biodiscovery --- Swinglea glutinosa --- dereplication --- acridones --- phenylacrylamides