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Growth plate --- Wounds and injuries.

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Bone Development. --- Extremities --- Sense Organs --- Bone Growth --- Bone and Bones --- Calcification, Physiologic --- Growth Plate --- growth & development. --- growth & development --- Vertebrates --- Bone Development

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This comprehensive reference work covers all aspects of growth plate fractures and their complications. Following general reviews of growth plate fractures, 21 chapters deal with each epiphyseal growth plate in the body. All of these chapters are constructed similarly for easy and quick retrieval of the required information. The main emphasis is on evaluation (diagnosis) and management (treatment). A separate section is devoted to premature partial physeal arrest, as this is by far the most common and feared complication of a growth plate fracture and its treatment is involved and controversial. The case studies included are often based on 20- to 30-year follow-ups, revealing cases that originally appeared to be quite satisfactory at the conclusion of growth but were found to have turned out quite poorly years later.  This unique text is an essential and excellent resource for any pediatric orthopedic surgeon as well as all personnel in the emergency room.

Growth plate --- Fractures. --- Wounds and injuries. --- Cartilago epiphysialis --- Epiphyseal cartilage --- Epiphyseal plate --- Growth cartilage --- Bones --- Orthopedic surgery. --- Orthopedics. --- Pediatrics. --- Surgical Orthopedics. --- Operative orthopedics --- Orthopedics --- Surgery, Operative --- Paediatrics --- Pediatric medicine --- Medicine --- Children --- Orthopaedics --- Orthopedia --- Surgery --- Diseases --- Health and hygiene

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Age Determination by Skeleton --- Knee Joint --- Bone Development. --- 612.6 --- Knee --- -Skeletal maturity --- Bone age of human beings --- Maturity, Skeletal --- Skeletal age of human beings --- Age --- Bones --- Human beings --- Human skeleton --- Genu --- Genus (Anatomy) --- Knee joint --- Joints --- Leg --- Stifle joint --- Bone Growth --- Bone and Bones --- Calcification, Physiologic --- Growth Plate --- methods. --- growth & development. --- Voortplanting. Groei. Ontwikkeling --- Aging --- Growth --- Age determination --- growth & development --- Skeletal maturity. --- Age determination by skeleton --- Aging. --- Methods --- Collected works. --- Growth and development --- Skeletal maturity --- Bone Development --- methods

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The Hedgehog signaling pathway is an evolutionarily conserved pathway that governs complex developmental processes, including stem cell maintenance, proliferation, differentiation, and patterning. Several recent studies have shown that the aberrant activation of Hedgehog signaling is associated with neoplastic transformation, cancer cell proliferation, metastasis, multiple cancers’ drug resistance, and survival rates. This book focuses on several aspects of Hedgehog signaling in organogenesis and the tumor microenvironment, and presents reviews and original papers on recent efforts in the field of Hedgehog signaling.

Cyp26 enzymes --- congenital anomalies --- CRE/LoxP --- hedgehog signaling --- mouse models --- retinoic acid --- smoothened --- sonic hedgehog --- sonic hedgehog (SHH) --- oral squamous cell carcinoma (OSCC) --- tumor microenvironment (TME) --- tumor-associated macrophages (TAMs) --- cancer-associated fibroblasts (CAFs) --- tumor-associated angiogenesis --- hedgehog --- growth plate --- endochondral ossification --- chondrocyte --- osteoblast --- bone disease --- TMJ --- synovial joint --- articular disc --- Ihh --- PTHrP --- osteoarthritis --- epithelial–mesenchymal interaction (EMI) --- prostate cancer --- external genitalia --- androgen --- basement membrane --- bone morphogenetic protein --- stem cell --- animal experiment --- fracture healing --- cancer stem cells --- hypospadias --- urethra --- penis --- bone --- hedgehog signalling --- tooth development --- epithelial and mesenchymal interaction --- Gli1 --- mesenchymal stem cell --- lineage tracing analysis --- stem cell marker --- n/a --- epithelial-mesenchymal interaction (EMI)