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Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. Antibody Engineering provides a comprehensive toolbox covering the well-established basics but also many exciting new techniques. The protocols reflect the latest "hands on" knowledge of key laboratories in this still fast-moving field. Newcomers will benefit from the proven step-by-step protocols, which include helpful practical advice; experienced antibody engineers will appreciate the new ideas and approaches. The book is an invaluable resource for all those engaged in antibody research and development.
Immunology. --- Monoclonal antibodies. --- Biotechnology. --- Antibodies. --- Chemical engineering --- Genetic engineering --- Antibodies, Monoclonal --- Monoclonal immunoglobulins --- Immunoglobulins --- Molecular cloning --- Immunobiology --- Life sciences --- Serology --- Recombinant antibodies --- Antibodies --- DNA, Recombinant --- Antibody Formation --- Genetic Engineering --- 57.083 --- Genetically engineered antibodies --- Recombinant immunoglobulins --- Recombinant proteins --- 57.083 Microbiological, virological, immunological methods and techniques --- Microbiological, virological, immunological methods and techniques --- genetics --- immunology --- methods
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There are many principles and applications of recombinant antibodies for infectious diseases. The preferred technology associated to recombinant antibody generation is mainly phage display. The adaptation of antibodies for infectious diseases is an area lacking information as most literature is focused on oncology or autoimmunity. This project highlights the power and potential of antibody phage display for infectious diseases. In addition to that, supplementary information regarding technologies associated to antibody generation and engineering in the context of infectious disease will also help to provide greater insight to the potential of recombinant antibodies for infectious diseases.
Recombinant antibodies. --- Communicable diseases. --- Medicine. --- Antibodies. --- Infectious diseases. --- Biomedicine. --- Infectious Diseases. --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Antigens --- Bacterial immunoglobulin-binding proteins --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Genetically engineered antibodies --- Recombinant immunoglobulins --- Immunoglobulins --- Recombinant proteins --- Monoclonal antibodies. --- Emerging infectious diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Antibodies, Monoclonal --- Monoclonal immunoglobulins --- Molecular cloning
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