Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Population genetics --- Genetics --- Heredity --- Genètica de poblacions humanes --- Índia --- Genètica de poblacions --- Genètica humana --- Consanguinitat --- Bharat --- República de la India --- República de l'Índia --- Àsia del Sud --- Ajantha (Índia) --- Assam (Índia : Estat) --- Brahmaputra (Àsia : Curs d'aigua) --- Calcuta (Índia) --- Delhi (Índia) --- Kodagu (Índia : Regió) --- Goa (Índia : Estat) --- Jammu i Caixmir (Índia : Estat) --- Kerala (Índia : Estat) --- Madràs (Índia) --- Madhya Pradesh (Índia : Estat) --- Maharashtra (Índia : Estat) --- Orissa (Índia : Estat) --- Panjab (Índia : Estat) --- Rajasthan (Índia : Estat) --- Uttar Pradesh (Índia : Estat) --- Caixmir (Àsia : Regió)

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book examines the utility of genome-wide association studies (GWAS) in the era of next-generation sequencing and big data, identifies limitations and potential means of overcoming them, and looks to the future of GWAS and what may lay beyond. GWAS are among the most powerful tools for elucidating the genetic aspects of human and disease diversity. In Genome-Wide Association Studies, experts in the field explore in depth the impacts of GWAS on genomic research into a variety of common diseases, including cardiovascular, autoimmune, diabetic, cancer, and infectious diseases. The book will equip readers with a sound understanding both of the types of disease and phenotypes that are suited for GWAS and of the ways in which a road map resulting from GWAS can lead to the realization of personalized/precision medicine: functional analysis, drug seeds, pathway analysis, disease mechanism, risk prediction, and diagnosis.

Medical genetics. --- Genomics. --- Genome research --- Genomes --- Molecular genetics --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Research --- Genetic aspects --- Human genetics. --- Cancer research. --- Immunology. --- Human Genetics. --- Cancer Research. --- Immunobiology --- Life sciences --- Serology --- Cancer research --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Genètica humana --- Antropologia física --- Biologia humana --- Genètica --- Herència humana --- Citogenètica humana --- Cromosomes humans --- Genètica de poblacions humanes --- Genètica mèdica --- Genètica molecular humana --- Psicologia genètica --- Genoma humà

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people.

Nervous system --- Degeneration --- Organs (Anatomy) --- Neurosciences --- Neurosciences. --- Human genetics. --- Human Genetics. --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Genètica humana --- Neurociències --- Neurologia geriàtrica --- Bioinformàtica --- Neurogeriatria --- Geriatria --- Neurologia --- Informàtica biològica --- Ciències de la informació --- Biologia computacional --- Neurociència --- Ciències neurològiques --- Ciències de la salut --- Neuroanatomia --- Neurobiologia --- Neurociència computacional --- Neuroendocrinologia --- Neurofarmacologia --- Neurogenètica --- Neuroquímica --- Sistema nerviós --- Antropologia física --- Biologia humana --- Genètica --- Herència humana --- Citogenètica humana --- Cromosomes humans --- Genètica de poblacions humanes --- Genètica mèdica --- Genètica molecular humana --- Psicologia genètica --- Genoma humà --- Medical genetics. --- Neuroscience. --- Medical Genetics. --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Pathology --- Genetic disorders --- Genetic aspects

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This volume is about DNA damage and repair. It covers recent advances in several important research areas of this rapidly expanding field, and does so at several levels, from individual molecules to organisms. The topics include mechanisms of damage recognition by DNA repair enzymes, chromatin response to DNA damage, special ways of mutagenesis, biomarkers of genotoxicity, and the integrated organism response to genotoxic and other kinds of stress. The book starts with two chapters about structural and mechanistic features of protein–DNA interactions that ensure fast and reliable discrimination between targets – be it DNA modifications or specific sequences – and non-targets. Examples of particular proteins and their function in repair regulation, translesion synthesis and chromatin remodeling are discussed in the following three chapters. Next, more attention is given to the mutagenic consequences of failed or aberrant DNA repair, particularly in mitochondria and in runs of trinucleotide repeats. Moving to a human health-oriented view, the book presents data on two kinds of lesions, the widely found 8-oxoguanine and the dietary genotoxic adducts with aristolochic acids, as biomarkers of general oxidative stress and specific exposure, respectively. Two final chapters are devoted to the interplay of multiple factors, including genotoxic stress, in the complex phenotypes in humans (amyotrophic lateral sclerosis ) and plants (abiotic stress response). This volume will be of significant interest for scientists working in the field of DNA repair as well as for the general biochemistry and molecular biology audience.

Human genetics. --- Cell biology. --- Biochemistry. --- Molecular biology. --- Cancer research. --- Human Genetics. --- Cell Biology. --- Biochemistry, general. --- Molecular Medicine. --- Cancer Research. --- Cancer research --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Composition --- Cytology. --- Reparació de l'ADN --- Genètica humana --- Antropologia física --- Biologia humana --- Genètica --- Herència humana --- Citogenètica humana --- Cromosomes humans --- Genètica de poblacions humanes --- Genètica mèdica --- Genètica molecular humana --- Psicologia genètica --- Genoma humà --- Mecanismes de reparació de l'àcid desoxiribonucleic --- Reparació de l'àcid desoxiribonucleic --- Genètica bioquímica --- Medicaments antineoplàstics

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Cancer --- Research. --- Cancer research --- Genètica humana --- Càncer --- Carcinoma --- Carcinosi --- Tumors --- Càncer d'ossos --- Càncer de cap --- Càncer de coll --- Càncer de bufeta --- Càncer de fetge --- Càncer de laringe --- Càncer de mama --- Càncer de pàncrees --- Càncer de pell --- Càncer de pròstata --- Càncer de pulmó --- Càncer de ronyó --- Càncer de tiroide --- Càncer d'ovari --- Càncer gastrointestinal --- Càncer ginecològic --- Càncer en els adolescents --- Càncer en els infants --- Medicaments antineoplàstics --- Melanoma --- Leucèmia --- Sarcoma --- Carcinògens --- Cèl·lules canceroses --- Cirurgia oncològica --- Infermeria oncològica --- Malalts de càncer --- Metàstasi --- Oncologia --- Antropologia física --- Biologia humana --- Genètica --- Herència humana --- Citogenètica humana --- Cromosomes humans --- Genètica de poblacions humanes --- Genètica mèdica --- Genètica molecular humana --- Psicologia genètica --- Genoma humà