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Year: 2022 Publisher: London : IntechOpen,
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This book provides a glimpse into the dynamic process of genetic polymorphism by presenting studies carried out on different kinds of organisms at the DNA level or gene expression level. Chapters address such topics as genetic polymorphism in animals, gametocyte biomarkers, thrombotic disorders, prostate cancer, and more.
Book
Year: 2022 Publisher: London : IntechOpen,
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This book provides a glimpse into the dynamic process of genetic polymorphism by presenting studies carried out on different kinds of organisms at the DNA level or gene expression level. Chapters address such topics as genetic polymorphism in animals, gametocyte biomarkers, thrombotic disorders, prostate cancer, and more.
Book
Year: 2022 Publisher: London : IntechOpen,
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This book provides a glimpse into the dynamic process of genetic polymorphism by presenting studies carried out on different kinds of organisms at the DNA level or gene expression level. Chapters address such topics as genetic polymorphism in animals, gametocyte biomarkers, thrombotic disorders, prostate cancer, and more.
Book
ISBN: 9789176855553 Year: 2017 Publisher: Linkopings Universitet
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This medical dissertation by Renate Slind Olsen investigates circulating and genetic factors that may influence the prognosis of colorectal cancer (CRC). The study focuses on the potential roles of CD93, PLA2G4C, PDGF-D, and inflammatory cytokines in CRC progression. Findings suggest that specific genotypes of CD93 and PLA2G4C are associated with CRC severity and could help in predicting disease outcomes. Additionally, PDGF-D signaling and certain inflammatory cytokines, such as CCL1 and CCL24, are identified as significant in CRC progression and mortality. The research aims to enhance early diagnosis, prognosis, and follow-up strategies for CRC patients.
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ISBN: 9789176855300 Year: 2017 Publisher: Linkopings Universitet
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This thesis by Annica Blissing explores the biochemical and pharmacological aspects of thiopurine methyltransferase (TPMT), an enzyme crucial for the metabolism of thiopurines used in treating certain immune-related disorders and leukemias. It investigates the molecular basis for individual variations in drug response due to different natural variants of the TPMT enzyme, which can affect the efficacy and safety of thiopurine treatments. The work presents biophysical analyses of specific TPMT variants and introduces new methodological approaches for studying enzyme activity and ligand binding. The research aims to improve personalized medicine through better understanding of TPMT's role in drug metabolism.
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ISBN: 1789858925 1789858917 Year: 2020 Publisher: London, England : IntechOpen,
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Genetic polymorphisms. --- Polymorphisms, Genetic --- Population genetics
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ISBN: 1839688114 1839688106 Year: 2022 Publisher: London, England : IntechOpen,
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Genetic polymorphisms. --- Polymorphisms, Genetic --- Population genetics
ISBN: 0878936033 0878936041 Year: 1983 Publisher: Sunderland, MA : Sinauer,
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DNA --- Proteins --- Genetic polymorphisms --- Evolution --- Evolution
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ISBN: 3540129030 0387129030 3642515886 Year: 1984 Volume: vol 53 Publisher: Berlin Heidelberg Tokyo Springer
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Genetic polymorphisms --- Population genetics --- Evolution (Biology) --- Congresses. --- Statistical methods
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ISBN: 0632083603 9780632083602 Year: 1971 Publisher: Oxford ; London ; Edinburgh... [et al.] : Blackwell Scientific Publications,
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Evolution (Biology) --- Ecological genetics --- Variation (Biology) --- Genetic polymorphisms
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